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Environment and breast cancer - the role of xenooestrogens in breast cancer
Andrej Plesničar, Branko Družina, Viljem Kovač, Božo Kralj, 2002, original scientific article

Abstract: The survival rate of breast cancer patients has not changed much in the last few decades in developed countries. In order to improve the efficacy of breast cancer prevention and treatment, the role of xenooestrogens in the mechanisms of its development has been evaluated. These industrial chemical bear little structural resemblance to each other and bind to the oestrogen receptors of exposed cells and/or trigger oestrogenic responses in laboratory test systems. Exposure to xenooestrogens has been regarded as a risk factor for carcinogenesis and a preventable cause of breast carcinoma. Several epidemiological and experimental studies in in vivo and in vitro conditions of the influence of xenooestrogens on the occurrence of breast cancer have been conducted in the last decades and have shown ambiguous results. No increase of breast carcinoma incidence could be found in women who were exposed to relatively high concentrations of xenooestrogens for extended periods and small quantities of these compounds that are present in the environment probably cannot act as etiological agents for the occurence of this disease. A multi step approach is suggested regarding the sequence of studies and measures that should be taken to further assess the importance of xenooestrogens on breast cancer carcinogenesis.
Keywords: dojka, ksenoestrogeni, novotvorbe
Published in DiRROS: 31.01.2024; Views: 136; Downloads: 36
.pdf Full text (96,95 KB)

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Computer system for determination of hip joint contact stress distribution from antero-posterior pelvic radiograph
Aleš Iglič, Veronika Kralj-Iglič, 1999, original scientific article

Abstract: Background. A computer system HIPSTRESS is described. The system can be used for the determination of the contact stress distribution in the hip joint for a known body weight and some characteristic pelvic and hip geometrical parameters which can be determined directly from the standard antero-posteriorradiograph. Conclusions. The system can be applied in clinicalpractice to predict an optimal stress distribution in different operative interventions in the hip.
Published in DiRROS: 22.01.2024; Views: 150; Downloads: 41
.pdf Full text (349,89 KB)

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On mechanisms of cell plasma membrane vesiculation
Veronika Kralj-Iglič, Urška Batista, Henry Hägerstrand, Aleš Iglič, Janja Majhenc, Mihael Sok, 1998, original scientific article

Keywords: budding, membrane bilayer, vesiculation
Published in DiRROS: 19.01.2024; Views: 145; Downloads: 42
.pdf Full text (1,68 MB)

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Novejši nuklearno-medicinski postopki pri netipljivih lezijah v dojki
Barbara Vidergar-Kralj, Ivana Žagar, Andreja A. Schwarzbartl-Pevec, 2004, published scientific conference contribution

Published in DiRROS: 01.12.2023; Views: 144; Downloads: 57
.pdf Full text (640,90 KB)

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