11. Dedicated small bowel follow-through - experience of Clinical institute of radiology in LjubljanaMateja Koprivnik, Breda Jamar, 2003, original scientific article Abstract: Background. Small bowell is a difficult part of the alimentary tract to examine. Radiologic modality most commonly used has been the conventional small bowel follow-through (SBFT), which has often been done in a cursory manner, without fluoroscopy and manual palpation. The purpose of our study is to present dedicated SBFT and to assess its sensibility and specificity. Patients and methods. We analysed 35 dedicated SBFT, performed from April to September 2002, in patients. Findings were evaluated according to clinical follow-up, endoscopy and surgery. Results. Our findings were consistent with clinical follow-up, endoscopy and surgery in 33 patients. In 2 patients our findings were false negative. Our results show 89.5% sensitivity and 100% specifity. Conclusions. An adequate per-oral examination remains the most reliable toll for diagnostic evaluation of the small bowel.
Published in DiRROS: 06.02.2024; Views: 132; Downloads: 30
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12. TXM peptides inhibit SARS-CoV-2 infection, syncytia formation, and lower inflamatory consequencesTea Govednik, Duško Lainšček, Urška Kuhar, Marva Lachish, Sandra Janežič, Malan Štrbenc, Uroš Krapež, Roman Jerala, Daphne Atlas, Mateja Manček Keber, 2024, original scientific article Abstract: After three years of the SARS-CoV-2 pandemic, the search and availability of relatively low-cost benchtop therapeutics for people not at high risk for a severe disease are still ongoing. Although vaccines and new SARS-CoV-2 variants reduce the death toll, the long COVID-19 along with neurologic symptoms can develop and persist even after a mild initial infection. Reinfections, which further increase the risk of sequelae in multiple organ systems as well as the risk of death, continue to require caution. The spike protein of SARS-CoV-2 is an important target for both vaccines and therapeutics. The presence of disulfide bonds in the receptor binding domain (RBD) of the spike protein is essential for its binding to the human ACE2 receptor and cell entry. Here, we demonstrate that thiol-reducing peptides based on the active site of oxidoreductase thioredoxin 1, called thioredoxin mimetic (TXM) peptides, can prevent syncytia formation, SARS-CoV-2 entry into cells, and infection in a mouse model. We also show that TXM peptides inhibit the redox-sensitive HIV pseudotyped viral cell entry. These results support disulfide targeting as a common therapeutic strategy for treating infections caused by viruses using redox-sensitive fusion. Furthermore, TXM peptides exert anti-inflammatory properties by lowering the activation of NF-κB and IRF signaling pathways, mitogen-activated protein kinases (MAPKs) and lipopolysaccharide (LPS)-induced cytokines in mice. The antioxidant and anti-inflammatory effects of the TXM peptides, which also cross the blood-brain barrier, in combination with prevention of viral infections, may provide a beneficial clinical strategy to lower viral infections and mitigate severe consequences of COVID-19.
Keywords: SARS-CoV-2, Disulfides, Thiol-reacting compound, Spike, Anti-inflammatory activity
Published in DiRROS: 06.02.2024; Views: 184; Downloads: 88
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13. Primary non-Hodgkin lymphoma of the cecum: a case reportMateja Kropivnik, Breda Jamar, Bojana Černelč, 2002, professional article Abstract: Background. Primary lymphoma of the colon is rare, constituting 0.4 % of primary colonic malignancies and usually involves cecum or rectum. The aim of this paper is to present the role and the importance of double contrast bariumenema (DCBE) in the diagnostic process. Case report. A 77 years old malewas admitted because of suspected inflammation in the area of total endoprosthesis of the left hip, inserted ten years before. Listeria monocytogenes was isolated from the aspirate and the patient treated with antibiotics. Twenty years ago the patient underwent nephrectomy because of hypernephroma of left kidney. At the time of admission he had sideropenic anaemia and he was febrile. Conclusion. The patient underwent many diagnostic procedures: ultrasound (US), computed tomography (CT), double contrast barium enema, which showed a tumour in the cecum, small bowel follow-through and scintigraphy. The diagnosis of primary non-Hodgkin lymphoma was established byhistology after biopsy at colonoscopy.
Published in DiRROS: 31.01.2024; Views: 166; Downloads: 27
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14. Surovinske potrebe za zagotavljanje prehoda na trajnostno in pametno mobilnost : zbornik povzetkov konferenčnih prispevkov2022, other monographs and other completed works Abstract: EIT Urbana mobilnost RIS Hub Slovenija, koordinirana s strani Zavoda za gradbeništvo Slovenije, deluje kot nacionalna kontaktna točka za skupnost urbana mobilnost, ki deluje pod okriljem Evropskega inštituta za inovacije in tehnologijo. Osredotočenost na izboljševanje življenjskih razmer v mestih, spodbujanje inovacij na področju zelenih in varnih rešitev za mobilnost ljudi, blaga in odpadkov, pospeševanje tržnih priložnosti v avtomobilski industriji ter oblikovanje zakonodajnega okvira za spremembe so le nekateri strateški cilji skupnosti KIC EIT Urbana mobilnost. Z namenom spodbujanja povezovanja, združevanja in povečevanja partnerstva med obema sektorjema (surovine in mobilnost), neposredno vpletenima v prehod na bolj trajnostne oblike mobilnosti, je bila 24. oktobra 2022 organizirana spletna konferenca EIT OPEN DAY SLOVENIJA2022 – Surovinske potrebe za zagotavljanje prehoda na trajnostno in pametno mobilnost. Konferenca je bila organizirana s strani Zavoda za gradbeništvo Slovenije, v sodelovanju z Regionalnim centrom Adria EIT Surovine RIS Hub in Javno agencijo SPIRIT Slovenija. Dogodek je bil razdeljen v štiri segmente, v okviru katerih je obravnaval finančne spodbude in mehanizme za zagotavljanje trajnostnega prehoda, tudi z uporabo novih in inovativnih lahkih zlitin ter vodikovih in baterijsko-električnih tehnologij.
Keywords: urbana mobilnost, pametna mobilnost, trajnostna mobilnost, mesta, trajnostni razvoj, urbano okolje, surovine, lahke zlitine, vodikove tehnologije, baterijsko električne tehnologije
Published in DiRROS: 25.01.2024; Views: 175; Downloads: 87
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15. Mud from the Sitarjevec mine as a pigment for textile printingDarja Rant, Mateja Štefančič, Vesna Zalar Serjun, Mateja Golež, 2021, published scientific conference contribution Abstract: The Sitarjevec mine, located near the town of Litija (Central Slovenia), is recognized by the strong yellow colour of its dripstone structures and mine mud deposits. The mine mud, composed predominantly of goethite, accumulates on the ground of the mine shafts as the result of the interaction between percolating underground water, iron ore minerals and microorganisms. Since the accumulation of limonite mine mud is an ongoing process, larger quantities of mud have been deposited in the mine shafts since its closure. These deposits present a real threat of unleashing a mine mud spill on the town of Litija. Such a scenario has already previously occurred. In order to find new potential routes for recycling larger quantities of this mine mud, the present research work was performed to assess the use of mine mud as a pigment in the dye industry. In the first stage, the chemical (XRF) and microstructural (SEM) characteristics of the mine mud were defined together with the identification of its phase composition (XRD), particle size distribution and specific surface area (BET). Furthermore, the pigment was used to colour textile printing paste on a laboratory scale. To define the most appropriate quality of textile prints the rheological response of the various textile printing paste samples was investigated in terms of their plastic viscosity, indicating their suitability for use in textile printing. Test prints wereconducted, and the properties of leaching and fastness in the prints were assessed.
Keywords: mine mud, recycling, pigment, printing paste, textile, rheology
Published in DiRROS: 25.01.2024; Views: 180; Downloads: 107
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18. Climate change increases the number of landslides at the juncture of the Alpine, Pannonian and Mediterranean regionsMateja Jemec Auflič, Nejc Bezak, Ela Šegina, Peter Frantar, Stefano Luigi Gariano, Anže Medved, Tina Peternel, 2023, original scientific article Abstract: During the next few decades, changes in rainfall frequency and magnitude are expected to have major impacts on landscape evolution, social, and economic aspects of human society. We focus on seasonal rainfall variations by the end of the twenty-first century to define affected landslide-prone areas, future landslide alerts and the impact of landslides on landscape development in the juncture of the Alpine, Pannonian, and Mediterranean region. A moderate and a worst-case climate scenario from CMIP5 global climate simulations were considered to determine the impact of rainfall on the two most common types of landslides in region, shallow and deep-seated landslides. The observed changes in the occurrence of shallow landslides are significant, especially in the winter months, where we can expect more landslide-prone areas compared to the baseline period. Shallow landslides will have a greater impact on the landscape in spring and summer than deep-seated landslides, especially in vineyards.
Keywords: podnebne spremembe, zemeljski plazovi
Published in DiRROS: 04.01.2024; Views: 250; Downloads: 60
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19. Application of multivariate statistical methods for determining geochemical trends of elements on the territory of SloveniaRobert Šajn, Mateja Gosar, Jasminka Alijagić, Tamara Teršič, 2024, original scientific article Abstract: The main objective of this study is to map multi-element geochemical anomalies in soil on a regional scale. We aimed to determine and evaluate the baseline geochemical values and main geochemical trends in soil that may serve as reference values against any future changes. A total of 817 topsoil samples (0–10 cm) were collected in a 5 × 5 km grid and analyzed for 35 elements using ICP-ES after multi-acid digestions (HClO4/HNO3/HCl/HF) and 53 elements using ICP-MS after modified aqua regia digestion (HCl/HNO3/H2O). The analytical results for the two different digestion methods (multi-acid digestion vs. aqua regia) were also compared for each chemical element. Multivariate statistical methods were applied to identify the geochemical trends and main sources of trace elements over the territory of Slovenia. Based on these results, seven natural and one mixed natural/anthropogenic geochemical association were established. The contents and trends of the determined factors are presented according to 8 natural units, 4 drainage areas, and geological units characteristic of Slovenia. The identified anthropogenic geochemical association combines toxic elements (Ag, Bi, Cd, Hg, P, Pb, S, Sn, and Zn). Increased values of these elements can be found in mining areas and metallurgic centers, in Quaternary sediments of the Sava River, and Adriatic Basin as the consequence of past mining activities and in the Julian Alps, where their origin could be connected to the atmospheric deposition.
Keywords: soil, geochemical mapping, distribution of geochemical elements, factor analysis, cluster analysis
Published in DiRROS: 04.01.2024; Views: 205; Downloads: 52
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20. Attitudes of Slovenian school children towards forests and climate change : a study by the Forest of experimentsBoris Rantaša, Ajša Alagić, Amina Gačo, Martin Jež, Mateja Kraševec, Urša Vilhar, 2023, other monographs and other completed works Keywords: forestst, climate changes, school children, Slovenia, environmental education, forest pedagogy, Slovenian Forestry Institute, Forest of experiments, LIFE SySTEMiC
Published in DiRROS: 15.12.2023; Views: 263; Downloads: 74
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