1701. The timeline of non-vocal and vocal communicative skills in infants with hearing lossAmanda Saksida, Roberta Rebesco, Arianna Colombani, Sara Pintonello, Eleonora Tonon, Andrea Martina Santoro, Eva Orzan, 2024, original scientific article Abstract: Background and aim: This study explores healthcare professionals' perspectives on end-of-life care in pediatric intensive care units (ICUs) in Croatia, aiming to illuminate their experiences with such practices, underlying attitudes, and major decision-making considerations. Amid the high variability, complexity, and emotional intensity of pediatric end-of-life decisions and practices, understanding these perspectives is crucial for improving care and policies. Methods: The study utilized a cross-sectional survey intended for physicians and nurses across all pediatric ICUs in Croatia. It included healthcare professionals from six neonatal and four pediatric ICUs in total. As the data from neonatal and pediatric ICUs were examined jointly, the term pediatric ICU was used to denominate both types of ICUs. A statistical analysis was performed using Python and JASP, focusing on professional roles, professional experience, and regional differences. Results: The study included a total of 103 participants (with an overall response rate-in relation to the whole target population-of 48% for physicians and 29% for nurses). The survey revealed diverse attitudes toward and experiences with various aspects of end-of-life care, with a significant portion of healthcare professionals indicating infrequent involvement in life-sustaining treatment (LST) limitation discussions and decisions, as well as somewhat ambiguous attitudes regarding such practices. Notably, discrepancies emerged between different professional roles and, in particular, regions, underscoring the high variability of LST limitation-related procedures. Conclusions: The findings highlight a pressing need for more straightforward guidelines, legal frameworks, support mechanisms, and communication strategies to navigate the complex terrain of rather burdensome end-of-life pediatric care, which is intrinsically loaded with profound ethical quandaries.
Keywords: communicative skills, language development, hearing loss, vocal skills, non-vocal skills, video analysis
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1702. Varuhinje Matere Zemlje : staroselke Latinske Amerike v boju za zaščito naraveTjaša Franko, 2024, original scientific article Abstract: Staroselska ljudstva predstavljajo le 6,2 % svetovnega prebivalstva, a varujejo 80 % biotske raznovrstnosti planeta. Pogosto so najmočnejša in edina obramba pred okoljskimi grozodejstvi. Pomembno zagovorniško vlogo imajo ravno ženske kot varuhinje in posredovalke tradicionalnega znanja naslednjim generacijam ter aktivistke za zaščito okolja pred podjetji, ki imajo gospodarske interese na območjih, bogatih z naravnimi viri. Ker nasprotujejo njihovemu izkoriščanju, so pogosto izpostavljene resnim varnostnim tveganjem, nasilju na podlagi spola in organiziranemu kriminalu. Prispevek obravnava aktivizem staroselk na področju varovanja narave na primerih staroselskih skupnosti v Ekvadorju in Mehiki.Indigenous peoples represent only 6.2% of the world’s population, but protect 80% of the planet’s biodiversity. They are often the strongest and only defence against environmental atrocities. Women play an important advocacy role in this regard, as guardians and transmitters of traditional knowledge to the next generation, and as activists to protect the environment from companies with economic interests in areas rich in natural resources. By opposing exploitation of the environment, these women are often exposed to serious security risks, gender-based violence and organized crime. This paper examines indigenous women’s activism in the field of nature protection through the cases of indigenous communities in Ecuador and Mexico.
Keywords: varovanje narave, staroselke, aktivizem, feminizem, Ekvador, Mehika, etnologija
Published in DiRROS: 08.07.2025; Views: 286; Downloads: 167
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1704. Effect of deep cryogenic treatment on aging behavior and properties of Al-Mg-Si alloyBojan Podgornik, Matic Klug Jovičević, Patricia Jovičević Klug, 2023, published scientific conference contribution Keywords: deep cryogenic treatment, Al-Mg-Si alloy, aging, microstructure, hardness, fatigue
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1709. Farmacevtske kompetence s področja laboratorijske medicine : razvoj, izobraževanje in pomen klinične biokemijeBorut Božič, Tjaša Debelak, 2025, review article Abstract: Reguliranost farmacevtskega poklica izhaja iz leta 2024 posodobljene Direktive 2005/36/EC o priznavanju poklicnih kvalifikacij. V programu usposabljanja farmacevtov je navedena tudi »Splošna in uporabna biokemija (medicinska)«, poznana pod izrazom klinična biokemija. Slednja je največja veja laboratorijske medicine, ki z analizo bioloških vzorcev pacienta prispeva k ugotavljanju zdravstvenega stanja preiskovanca v preventivi, diagnostiki, spremljanju zdravljenja in napovedovanju poteka bolezni. To področje pa ostaja kot kompetenca farmacevtov slabo poznano v strokovni javnosti. V prispevku so prikazane značilnosti razvoja laboratorijske medicine v evropskem in slovenskem prostoru z mejniki v razvoju klinične kemije in organiziranost njenega izobraževanja pri nas, ki se je začelo kot del študija farmacije. Posebej so izpostavljeni kompetenčni vidiki farmacevtov na področju laboratorijske diagnostike.
Keywords: izobraževanje, kompetence/kompetenčni modeli
Published in DiRROS: 08.07.2025; Views: 380; Downloads: 178
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1710. Inducirane pluripotentne matične celice pri odkrivanju in vrednotenju zdravilnih učinkovinJaka Rotman Primec, Zala Krajšek, Dunja Urbančič, 2025, review article Abstract: Inducirane pluripotentne matične celice so v zadnjih letih postale pomembno orodje za odkrivanje zdravilnih učinkovin, saj ponujajo bistvene prednosti pred tradicionalnimi modeli, kot so primarne celice, rakave celične linije in živalski modeli. Pridobimo jih z reprogramiranjem somatskih celic v pluripotentno stanje, kar omogoča njihovo diferenciacijo v različne tipe celic ob ohranjanju dedne informacije posameznika. Pri uporabi induciranih pluripotentnih matičnih celic za odkrivanje zdravilnih učinkovin je na voljo več modelov, vključno z dvodimenzionalnimi kulturami, enostavnejšimi tridimenzionalnimi modeli in naprednejšimi modeli – organi na čipu. Tovrstni modeli omogočajo natančnejšo oceno toksičnosti in učinkovitosti zdravilnih učinkovin, njihovih medsebojnih interakcij ter proučevanje mehanizmov bolezni. Izzivi, s katerimi se soočamo ob uporabi induciranih pluripotentnih matičnih celic, so: njihova nezadostna zrelost, variabilnost med pridobljenimi celičnimi linijami in visoki stroški, kar trenutno omejuje njihovo širšo uporabo v farmaciji. Kljub tem omejitvam imajo inducirane pluripotentne matične celice velik potencial za razvoj personaliziranih oblik zdravljenja in odkrivanje novih terapevtskih pristopov.
Keywords: celični modeli in vitro, inducirane pluripotentne matične celice, odkrivanje novih zdravilnih učinkovin, predklinične študije
Published in DiRROS: 08.07.2025; Views: 396; Downloads: 143
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