1171. A paraungual tumor? - No, just tungiasisRastko Golouh, Marko Špiler, 2000, professional article Abstract: Background. Tunga penetrans is a burrowing flea that is prevalent in Central and South America, the Caribbean, tropical Africa, India and Pakistan. Tungiasis results from cutaneous infestation by gravid female flea, Tunga penetrans. Case report. We report a case of tungiasis in a male who had been on a tourist expedition to Bolivia and Peru. The condition had manifested as aparaungual infiltration of a toe, that was clinically suspicious for tumor. Conclusions. Microscopic examination of the lesion and travel history led to the diagnosis of tungiasis. This is the first case report of Tunga penetrans infestation in Slovenia.
Published in DiRROS: 23.01.2024; Views: 242; Downloads: 56
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1172. Combined modality treatment with organ preservation in invasive bladder cancerTanja Čufer, 2000, original scientific article Abstract: Background. The standard treatment for muscle-invasive bladder cancer is stillradical cystectomy. However despite mutilating surgery half of the patients eventually develop metastatic disease and subsequently die of the disease. In view of these problems, a bladder-sparing approach using multi-modality treatment with transurethral resection (TUR), irradiation and chemotherapy has been tested in this disease. So far, the results published byfive groups, showed that the survival rates of patients treated by multi-modality therapy with a bladder sparing approach, based on the response to initial TUR and chemotherapy or chemoradiotherapy, are comparable to cystectomy series, while also offering a 60% to 70% chance of maintaining a functioning bladder. The probability of survival with bladder preserved was found to be around 40% at 5-years. The best predictor of successful multi-modality treatment with bladder preservation seems to be a complete response to initial therapy and a close cystoscopic surveillance is obligatoryto allow for cystectomy at earliest opportunity, if necessary. Conclusions. Multimodality treatment with selective bladder preservation offers a chance for long term cure and survival equal to radical cystectomy inmuscle invasive bladder cancer, while also offering a chance of maintaining a normally functioning bladder. It is expected, that the identification of biological factors with a predictive value for successful chemoradiation will allow for a better selection of patients who could benefit from this treatmentin future.
Published in DiRROS: 23.01.2024; Views: 238; Downloads: 62
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1173. Influence of hydralazine on interstitial fluid pressure in experimental tumors - a preliminary study : Vpliv hydralazina na tlak medcelične tekočine v poskusnih tumorjihBlaž Podobnik, Damijan Miklavčič, 2000, original scientific article Abstract: Background. Interstitial fluid pressure (IFP) has been recognised as the most important obstacle in macromolecular drug delivery to solid tumors. Our interest was to reduce differentialy tumor IFP with respect to IFP in surrounding and normal tissues in order to increase drug delivery to tumors aswell to increase tumor blood flow and potentialy tumor tissue oxygenation. In this preliminary study we used hydralazine, a longacting arterial vasodilator. Materials and methods. Measurements of interstitial fluid pressure were performed in vivo on CBA mice bearing SAF tumors using wick-in-needle technigue. Altogether eleven measurements were obtained on different animals with tumors of different size. Results. IFP in tumors after hydralazine administration was significantly lower than initial values in corresponding tumors. On average tumor IFP decreased for 33 % from initial value. On the contrary, no change in IFP in normal tissue was observed after hydralazine administration. Also, after injection of physiological saline instead of hydralazine there was no change in IFP neither in tumors nor in muscle. The results of our preliminary study on the effect of hydralazine on IFP in SAF tumor model is in accordance to previously reported studies. The decrease in tumor IFP was only observed in tumors, but not in muscle and surrounding subcutis. Conclusion. Hydralazine is a vasodilator which is capable of decreasing tumor IFP, reproducibly and with favorably long lasting dynamics.
Keywords: sarcoma, experimental drug therapy, hydralazine, extracellular space, interstitial fluid pressure, manometry
Published in DiRROS: 23.01.2024; Views: 274; Downloads: 69
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1175. Editorial : The intersection of cognitive, motor, and sensory processing in agingsUroš Marušič, Jeannette R. Mahoney, 2024, other scientific articles Keywords: aging, sensory performance, motor performance, cognitive performance, multisensory integration
Published in DiRROS: 22.01.2024; Views: 295; Downloads: 118
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1176. Electrochemical corrosion tests on steel in alkali-activated materialsNina Gartner, Miha Hren, Tadeja Kosec, Andraž Legat, 2021, published scientific conference contribution Abstract: One of the potential alternatives to Ordinary Portland Cement (OPC) are Alkali-Activated Materials (AAMs). The service life of reinforced concrete structures greatly depends on the corrosion resistance of embedded steel reinforcement. Due to the wide range of AAMs and their diverse properties, corrosion processes of steel in these materials are relatively unknown. Corrosion monitoring methods or their interpretations in certain cases cannot be directly transferred from the ones for OPC materials. The chemical compositions of pore solution in different AAMs influence the results of electrochemical measurements and their interpretations. Within this research, three different alkali-activated mortar mixes were prepared, based on fly ash, slag or metakaolin. Pore solutions were extracted from each mortar andchemical analysis was acquired. Different electrochemical corrosion measurements were performed on steel submerged to synthetic pore solutions. In parallel, ordinary carbon steel reinforcing bar was installed in the same types of alkali-activated mortar mixes. Specimens were exposed to wet/dry cycles with saline solution and periodic measurements of electrochemical impedance spectroscopy (EIS) were performed. Measured parameters in both systems were analysedand compared. It was concluded that electrochemical measurements in pore solutions can provide basic overview on corrosion behaviour in different AAMs environments. Periodic EIS measurements enabled monitoring of corrosion initiation and propagation on steel reinforcement in AAMs, although the information on the corrosion type is missing. Interpretation of results depends on visual analysis of corrosion damages after the end of exposure, providing information on corrosion type and intensity. The continuation of research on corrosion monitoring techniques will be performed by using Electrical Resistance (ER) sensors and Coupled Multi-Electrode Array (CMEA) sensors.
Keywords: corrosion, alkali-activated mortars, pore solution extraction, electrochemical corrosion techniques, visual analysis
Published in DiRROS: 22.01.2024; Views: 304; Downloads: 146
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1177. Influence of curing / drying methods including microwave heating on alkali activation of waste casting coresBarbara Horvat, Vilma Ducman, 2021, published scientific conference contribution Abstract: Within previous investigation alkali activation of waste casting cores at room temperature did not give promising results, i.e. when the precursor was gently ground and sieved below 600 %m the alkali activated material fell apart at demolding, and when the precursor was ground below 90 %m, the alkali activated material did not solidify in more than 2 years. , Therefore different drying/curing methods were applied to enhance the reaction. Waste casting cores were prepared in two granulations (sieved below 600 %m and below 90 %m), activated with Na -water glass and 10 M NaOH, cured at different temperatures (70 °C and room temperature), and subsequently cured/dried at three different conditions: room temperature, 110 °C, and irradiated with microwaves. The highest compressive strength, 25 MPa, was gained with subsequent curing/drying at 110 °C. The lowest density, 0.5 kg/l, with compressive strength above 3 MPa, was achieved with subsequent curing/drying with microwaves .
Keywords: waste casting cores, alkali activation, curing, drying, microwaves, mechanical strength
Published in DiRROS: 22.01.2024; Views: 285; Downloads: 151
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1178. Comprehensive permanent remote monitoring system of a multi-span highway bridgeAndrej Anžlin, Uroš Bohinc, Doron Hekič, Maja Kreslin, Jan Kalin, Aleš Žnidarič, 2021, published scientific conference contribution Abstract: As part of the reconstruction of a multi-span viaduct on a Slovenian highway, a permanent remote monitoring system with over 200 sensors was established. Several parameters are monitored on different parts of the viaduct by means of temperature sensors, accelerometers, strain gauges, long-gauge deformation and Fibre Bragg Grating (FBG) sensors. In this way strains, frequencies and temperatures on external prestressed beam cables, carbon fibre rebarsused for the flexural strengthening of a deck overhang, pier caps and prestressed beams are measured and stored into the on-site central data acquisition system. This paper presents architecture of the permanent bridge monitoring system and preliminary results of the measurements.
Keywords: permanent monitoring, structural health monitoring, bridge WIM, sensors, viaduct
Published in DiRROS: 22.01.2024; Views: 377; Downloads: 163
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1179. Evaluation of silicona microstrip detectors as X-ray sensors in digital mammographyTadej Mali, Vladimir Cindro, Marko Mikuž, Urban Zdešar, Breda Jančar, 1999, original scientific article Abstract: Background. Position sensitive silicon microstrip detectors are used as sensors for X rays in a digital imaging system. Silicon detectors were used inan edgeon geometry, yielding high X ray detection efficiency. Material and methods. A small detector system was assembled and tested. Images of a standard, 5 cm thick phantom were made and evaluated. It is demonstrated, thatthe use of silicon detectors in mammography could significantly contributeto a reduction of dose. All images were made with skin entrance doses lower than 1 mGy. Results and conclusion. Microcalcifications with a diameter of 350microm could still be detected with skin entrance doses of about 0.25 mGy. It was demonstrated that a 5 Ip/mm pattern can be detected. Image processing should further improve the image quality.
Published in DiRROS: 22.01.2024; Views: 332; Downloads: 63
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