1291. Ocena količinskega stanja podzemnih voda za Načrt upravljanja voda 2022–2027 (NUV III)Petra Souvent, Urška Pavlič, Mišo Andjelov, Nina Rman, Peter Frantar, 2023, original scientific article Abstract: Ocena količinskega stanja podzemnih voda je del Načrta upravljanja voda 2022–2027 (NUV III). Z njo po določenih kriterijih ovrednotimo količinsko stanje na 21 vodnih telesih podzemnih voda v Sloveniji kot »dobro« ali »slabo«. Ocena je izvedena s štirimi preizkusi, kjer analiziramo vpliv odvzemov (črpanih količin) podzemne vode na: količine podzemne vode in vodno bilanco, ekološko stanje površinskih vodnih teles, kopenske ekosisteme odvisne od podzemne vode in vdore slane vode ali vode slabše kakovosti v vodonosnik. Končno skupno oceno, na podlagi opravljenih preizkusov, določa kriterij najslabše ocene. Na podlagi rezultatov izvedenih preizkusov imamo 20 vodnih teles ocenjenih s skupno oceno »dobro«. Vodno telo Dravska kotlina pa je ocenjeno kot »slabo«, ker črpanje podzemne vode povzroča vdore vode slabše kakovosti v vodonosnik. Zadnja obdobna ocena količinskega stanja 1991–2020 razkriva, da imamo v plitvih vodonosnikih podzemnih vodnih teles letno na razpolago dobrih 4 milijarde m3 podzemne vode. Odvzemi podzemne vode (črpane količine) so v obdobju 2014–2019 v plitvih vodonosnikih dosegali povprečno 135 milijonov m3/leto. Na območju globokega geotermalnega vodonosnika v Murski kotlini so odvzemi v tem obdobju ocenjeni na 2,5 milijona m3/leto. Numerični modeli simulirajo omejeno napajanje, ki se kaže kot izcejanje iz okoliških kamnin v geotermalni vodonosnik v višini približno 2,3 milijona m3 termalne vode na leto.
Keywords: podzemna voda, vodno telo, preizkus količinskega stanja, vodna bilanca, ekosistemi, odvzemi
Published in DiRROS: 16.01.2024; Views: 313; Downloads: 107
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1294. Effect of the type of application of Newcastle disease virus on the Ehrlich ascites tumorTomaž Milanez, Robert Košak, Anton Cerar, 1996, original scientific article Abstract: Newcastle disease virus (NDV) has been shown to have an inhibitory effect on the tumours. Most authors use peritumoral application of virus. The purpose of our studz was to compare the effects of the ip in contrast to sc application of the virus on the ip and sc transplanted Ehrlich ascites tumor (EAT) in CBA/H mouse. We measured the length of survival, the tumor cure rates, the metastatic rate, and the frequencz of ascites and sc tumors in the site of ip EAT injection. Prolongation of survival after the therapy with NDV in ip transplanted EAT average time of survival in control group was 70.5 days, and 107 and 79.9 days with ip and sc NDV virus therapy respectively. The differences were significant only between control group and the group treated with ip application of NDV. Tumor cure rates were: ipNDV group 30%, scNDV group 20% and control group 5%. NDV therapy in sc transplanted EAT prolonged the time of survival; in control group it was 63.3 days, and 75.2 and 65.9 days with ip and sc NDV therapy respectively. NDV therapy inhibited metastatic rate of ip transplanted EAT. Inhibition was more effective with ip application of NDV. VIrus therapz also lowered the frequencz of appearance of ascites and sc tumour in the site of ip EAT injevtion. In sc transplanted EAT ip application of NDV inhibited the metastatic rate while in sc applied NDV some stimulation of metastasation was found. Ip application of NDV was found to be superior in contrast to sc application in all its therapeutic effects against EAT. Our results show that the tumor inhibition of NDV, in the system we used, has the characteristics of the biological response modifiers.
Published in DiRROS: 16.01.2024; Views: 275; Downloads: 70
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1296. Differential diagnosis between bone metastases and osteomalaciaBranko Zakotnik, Simona Borštnar, Tadeja Movrin, Boris Jančar, Andreja Zidar, 1996, original scientific article Abstract: In oncology the diagnosis of skeletal metastases is a frequent one, in infact so frequent that other diagnoses such as metabolic bone diseases affecting patients with cancer may be overlooked. In our report two cases of osteomalacia referred to an oncologist are presented; in both of them the diagnosis of diffuse bone metastases of unknown origin was suspected. The differential diagnosis is discussed and the importance of bone marrow biopsy using Yamshidi needle for diagnosis of metabolic bone disease is emphasized.
Published in DiRROS: 16.01.2024; Views: 307; Downloads: 72
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1297. Advantages and disadvantages of hormone replacement therapySonja Bebar, Marjetka Uršič-Vrščaj, 1996, review article Abstract: In the developed countries, more than 30% of female population is in the postmenopusal period of their life. Approximately one third of these present with severe clinical menopausal symptoms, such as hot flushes, sleeplessness, night sweats, and depression. Many women search medical help. By means of hormone replacement therapy (HRT), these problems can be either completely eliminated or alleviated in 90% of women. The suspected association between HRT and risk of carcinoma should be ignored, however. While estrogens in combination with progestogens exert a protective effec against ovarian and endometrial carcinomas, a possible correlation between HRT and breast cancer has not been fully explained yet. Nevertheless, some published reports have indicated a slightly increased risk of breast cancer after a prolonged use of HRT.
Published in DiRROS: 16.01.2024; Views: 258; Downloads: 61
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1298. Prognostic value of staging laparotomy in supradiaphragmatic clinical stage I and II Hodgkin's diseaseMarjeta Vovk, Tatjana Šumi-Križnik, Marija Jenko-Fidler, Gabrijela Petrič-Grabnar, Marinka Kremžar, Janez Novak, Mojca Senčar, Branko Zakotnik, Alenka Vodnik-Cerar, Branimir Jakšić, 1996, original scientific article Abstract: In the period 1974-1989, 219 patients with supradiaphragmatic clinical stage I and II Hodgkin's disease were treated at the Institute of Oncology in Ljubljana; of these 95 (43%) patients underwent staging laparotomy. Of laparotomized patients, those with pathological stage III-IV, and of non-laparotomized, those with unfavorable prognostic factors (B-symptoms, bulky mediastinum) received chemotherapy: the remaining patients were treated by irradiation. No statistically significant difference in the survival and disease-free survival between laparotomized and nonlaparotomized patients could be found.
Published in DiRROS: 16.01.2024; Views: 253; Downloads: 61
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1299. Gastric emptying in rats with gastroduodenal disease induced by N-methyl-N-nitro-N-nitrosoguanidine and alcoholDražigost Pokorn, Anton Cerar, 1996, original scientific article Abstract: The rate of gastric emptying was measured with a dye dilution technique in rats treated with N-methyl-N-nitro-N-nitrosoguanidine and alcohol. Gastric emptying was compared in rats with gastroduodenal inflamatory diseases and gastroduodenal neoplasms, and in those without gastroduodenal disease. Gasttric emptying was found to be significantly increased following the intragastric injection of liquid meal in rats with gastroduodenal diseases as opposed to the control group of healthy rats. These findings suggest than an increased gastric emptying of liquids can be explained by abolition on the relaxation of the gastric wall in rats with gastroduodenal diseases.
Published in DiRROS: 16.01.2024; Views: 215; Downloads: 75
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