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1.
Pelagic calcifiers face increased mortality and habitat loss with warming and ocean acidification
Nina Bednaršek, Brendan Carter, Ryan M. McCabe, Richard Alan Feely, Evan M. Howard, Francisco P. Chavez, Meredith Elliott, Jennifer L. Fisher, Jaime Jahncke, Zach Siegrist, 2022, original scientific article

Abstract: Global change is impacting the oceans in an unprecedented way, and multiple lines of evidence suggest that species distributions are changing in space and time. There is increasing evidence that multiple environmental stressors act together to constrain species habitat more than expected from warming alone. Here, we conducted a comprehensive study of how temperature and aragonite saturation state act together to limit Limacina helicina, globally distributed pteropods that are ecologically important pelagic calcifiers and an indicator species for ocean change. We co-validated three different approaches to evaluate the impact of ocean warming and acidification (OWA) on the survival and distribution of this species in the California Current Ecosystem. First, we used colocated physical, chemical, and biological data from three large-scale west coast cruises and regional time series; second, we conducted multifactorial experimental incubations to evaluate how OWA impacts pteropod survival; and third, we validated the relationships we found against global distributions of pteropods and carbonate chemistry. OWA experimental work revealed mortality increases under OWA, while regional habitat suitability indices and global distributions of L. helicina suggest that a multi-stressor framework is essential for understanding pteropod distributions. In California Current Ecosystem habitats, where pteropods are living close to their thermal maximum already, additional warming and acidification through unabated fossil fuel emissions (RCP 8.5) are expected to dramatically reduce habitat suitability.
Keywords: California current ecosystem, climate change, global data synthesis, habitat loss, habitat suitability modeling, multiple stressors, ocean acidification, pelagic calcifiers, pteropods, species distribution, warming
Published in DiRROS: 17.07.2024; Views: 112; Downloads: 160
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2.
Current and innovative approaches in the treatment of non-muscle invasive bladder cancer : the role of transurethral resection of bladder tumor and organoids
Milena Taskovska, Mateja Erdani-Kreft, Tomaž Smrkolj, 2020, review article

Abstract: Background. Bladder cancer is the 7th most common cancer in men. About 75% of all bladder cancer are nonmuscle invasive (NMIBC). The golden standard for definite diagnosis and first-line treatment of NMIBC is transurethral resection of bladder tumour (TURB). Historically, the monopolar current was used first, today bipolar current is preferred by most urologists. Following TURB, depending on the tumour grade, additional intravesical chemo- or/and immunotherapy is indicated, in order to prevent recurrence and need for surgical resection. Development of new technologies, molecular and cell biology, enabled scientists to develop organoids % systems of human cells that are cultivated in the laboratory and have characteristics of the tissue from which they were harvested. In the field of urologic cancers, the organoids are used mainly for studying the course of different diseases, however, in the field of bladder cancer the data are scarce. Conclusions. Different currents - monopolar and bipolar, have different effect on urothelium, that is important for oncological results and pathohistological interpretation. Specimens of bladder cancer can be used for preparation of organoids that are further used for studying carcinogenesis. Bladder organoids are step towards personalised medicine, especially for testing effectiveness of chemo-/immunotherapeutics.
Keywords: bladder cancer, transurethral resection of bladder tumour, monopolar/bipolar current, consensus molecular subtype
Published in DiRROS: 12.07.2024; Views: 101; Downloads: 72
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Factors influencing growth of mature sycamore trees (Acer pseudoplatanus L.) on carbonate bedrock
Aleš Kadunc, Marijan Kotar, 2005, original scientific article

Abstract: This paper presents the growth potential of sycamore (Acer pseudoplatanus L.) on four types of forest sites located on carbonate bedrock. The research covers sycamore sites (Aceri-Fraxinetum ill.), beech sites (Lamio orvalae-Fagetum), beech sites planted with Norway spruce, and silver fir-beechsites (Omphalodo-Fagetum aceretosum). The analyses for each forest type were carried out on five plots. Our aim was to determine the effect of site factors and stand parameters on sycamore growth. Site productivity (SP) is positively correlated with soil depth, coarse silt percentage in the cambichorizon, the content of phosphorus in leaves and, partly, with potassium. The effect of nitrogen supply on height growth or SP was not confirmed. Furthermore, height growth on sites with a higher rate of nutrient cycling, higher macronutrient supply and higher sand percentage in the cambic horizon is significantly faster. As to the growth of basal area, in addition to positive dependences of crown size, many other correlations with site factors were confirmed.
Keywords: beech stand, growing stock, stand value, current volume increment, current value increment, quality structure, social collective
Published in DiRROS: 12.07.2017; Views: 4681; Downloads: 1881
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