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371 - 380 / 2000
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371.
372.
Extracellular vesicle-derived bioactive molecules for corneal and ocular surface regeneration
Ana Kolenc, Živa Dimnik, Miha Marzidovšek, Petra Schollmayer, Marko Hawlina, Elvira Maličev, Zala Lužnik Marzidovšek, 2025, review article

Abstract: Cell-based therapies emerge as potential treatment options for various debilitating diseases. Preclinical research and clinical studies involving cells increased exponentially in the past decade. In addition to cell-based approaches, the use of extracellular vesicles (EVs), which are released by nearly all cell types, emerged as a promising cell-free alternative. Those approaches are also being explored in the field of ophthalmology. Several clinical trials involving EVs are underway to develop potential treatments for advanced ocular surface diseases, including corneal disorders, injuries, and dry eye disease. The cargo carried by EVs has been shown to include a diverse array of functional molecules such as transcription factors, cytokines, growth factors, mRNA, tRNA, rRNA, miRNA, and fragments of dsDNA. While the molecular composition of EVs is already well characterised, the specific activity of these molecules upon delivery to recipient cells remains poorly understood. In this review, we summarise recent studies investigating the bioactive molecules within EVs shown to influence or modulate cellular activity on the ocular surface. Among these, various miRNAs have most commonly been identified as therapeutic agents targeting distinct molecular pathways. The EVs studied were predominantly derived from various mesenchymal stem cells.
Keywords: extracellular vesicles, bioactive molecules, cornea, dry eye disease, miRNA, mesenchymal stem cells, ophthalmology
Published in DiRROS: 24.11.2025; Views: 129; Downloads: 65
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373.
Poročilo o preskusu št.: LVG 2025-136 : vzorec št. 2025/00114
Tine Hauptman, Maarten De Groot, 2025, expertise, arbitration decision

Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 24.11.2025; Views: 76; Downloads: 0
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374.
Poročilo o preskusu št.: LVG 2025-137 : vzorec št. 2025/00117
Tine Hauptman, Maarten De Groot, 2025, expertise, arbitration decision

Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 24.11.2025; Views: 76; Downloads: 0
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375.
Poročilo o preskusu št.: LVG 2025-140 : vzorec št. 2025/00118
Tine Hauptman, Maarten De Groot, 2025, expertise, arbitration decision

Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 24.11.2025; Views: 58; Downloads: 0
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376.
Poročilo o preskusu št.: LVG 2025-141 : vzorec št. 2025/00115
Tine Hauptman, Maarten De Groot, 2025, expertise, arbitration decision

Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 24.11.2025; Views: 68; Downloads: 0
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377.
Poročilo o preskusu št.: LVG 2025-142 : vzorec št. 2025/00111
Tine Hauptman, Maarten De Groot, 2025, expertise, arbitration decision

Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 24.11.2025; Views: 71; Downloads: 0
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378.
Editorial : databases and nutrition, volume II
Alessandra Durazzo, Igor Pravst, Massimo Lucarini, 2023, preface, editorial, afterword

Keywords: food data, food groups, nutrients, natural substances, dietary supplements, classification, categorization, food composition databases
Published in DiRROS: 24.11.2025; Views: 162; Downloads: 60
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379.
Poročilo o preskusu št.: LVG 2025-128 : vzorec št. 2025/00582
Tine Hauptman, 2025, expertise, arbitration decision

Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 24.11.2025; Views: 71; Downloads: 0
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380.
Poročilo o preskusu št.: LVG 2025-154 : vzorec št. 2025/00595
Tine Hauptman, Špela Hočevar, Patricija Podkrajšek, Barbara Piškur, 2025, expertise, arbitration decision

Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 24.11.2025; Views: 71; Downloads: 0
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