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1713. Structural basis of G-quadruplex recognition by a camelid antibody fragmentMojca Pevec, Tadej Medved, Matic Kovačič, Neža Žerjav, Jernej Imperl, Janez Plavec, Jurij Lah, Remy Loris, San Hadži, 2025, original scientific article Published in DiRROS: 07.07.2025; Views: 409; Downloads: 215
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1714. Srbija na istorijskoj prekretnici 1944: slom monarhista i pobeda komunističkih snagaNemanja Dević, 2024, original scientific article Abstract: Srbija se je sredi leta 1944 znašla na zgodovinski prelomnici. Odločitev zaveznikov, da podprejo komunistično stran, je pripomogla k izidu večletne državljanske vojne in omogočila komunistom prevzem oblasti v državi. Partizanske sile, ki so iz Bosne in Črne gore prodrle v Srbijo, so uspele dotlej prevladujočemu četniškemu gibanju zadati več velikih porazov. Vmes so se krepile tudi lokalne partizanske sile, ki so iz gverilskih odredov po zgledu drugih delov države prerasle v divizije in korpuse NOVJ. Končno jim je septembra 1944 na pomoč priskočila Rdeča armada, ki je pospešila osvoboditev in ključno prispevala k izgonu nemških okupacijskih sil. V prispevku želimo na podlagi obstoječe literature in arhivskih virov podati pregled razmer v Srbiji poleti in jeseni 1944 ter izpostaviti ključne dejavnike, ki so pripeljali do partizanskega prevzema oblasti.
Keywords: Srbija, druga svetovna vojna, leto 1944, četniki, partizani
Published in DiRROS: 06.07.2025; Views: 337; Downloads: 118
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1715. Biorafinerijski potencial manjvrednega lesa rdečega bora (Pinus sylvestris L.) in robinije (Robinia pseudoacacia L.) za pridobivanje naravnih bioaktivnih učinkovin za zaščito lesaViljem Vek, Ida Poljanšek, Urša Osolnik, Peter Hrovatič, Angela Balzano, Miha Humar, Primož Oven, 2025, review article Abstract: S prispevkom želimo predstaviti glavne rezultate in povzetek znanstvenih dognanj, do katerih smo prišli z dvema nacionalnima podoktorskima projektoma ob podpori takratnega Ministrstva za izobraževanje, znanost in šport Republike Slovenije (MIZŠ) ter Javne agencije za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije (ARIS). Analizirali smo biorafinerijski potencial manjvrednega lesa rdečega bora (Pinus sylvestris L.) in robinije (Robinia pseudoacacia L.) za ekstrakcijo naravnih bioaktivnih spojin. Les grč in jedrovine smo uporabili kot biomaso za ekstrakcijo polifenolnih ekstraktivov, ki smo jih nato uporabili v naravno osnovanih pripravkih za zaščito lesa. Rezultati so pokazali, da hidrofilni ekstraktivi grč bora in jedrovine robinije zavirajo glivni razkroj lesa in imajo velik potencial kot biocidne komponente in antioksidanti v naravno osnovanih zaščitnih pripravkih. Nadaljnje raziskave antioksidativnih in protiglivnih lastnosti ekstraktivov lesa in skorje so v teku.
Keywords: robinija, rdeči bor, grče, les, manjvredna drevesna biomasa, ekstrakcija, polifenoli, naravni fungicidi in antioksidanti, biorafinerija, krožno biogospodarstvo
Published in DiRROS: 04.07.2025; Views: 746; Downloads: 289
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1716. Leseni daljnovodni drogovi – analiza vzrokov za prezgodnji razkroj na območju SlovenijeMiha Humar, Boštjan Lesar, Nace Kregar, Simon Drnovšek, 2025, original scientific article Abstract: Študija se osredotoča na analizo vzrokov za prezgodnji propad lesenih daljnovodnih drogov v severovzhodni Sloveniji, kjer je bilo zabeleženih več primerov hitrega glivnega razkroja drogov, kljub načrtovani življenjski dobi 30 do 50 let. Drogovi so bili izdelani iz lesa rdečega bora in impregnirani z baker-etanolaminskim biocidnim proizvodom. Namen raziskave je bil oceniti stanje stoječih drogov in preučiti ključne vzroke za njihovo prezgodnjo degradacijo na primeru dveh podrtih drogov. Uporabljene metode vključujejo uporabo rezistografa za določanje razkrojenosti lesa po preseku, izolacija izvrtkov za določanje penetracije in retencije. Poleg tega je bila opravljena mikroskopska in hiperspektralna analiza na vzorcih lesa za natančno karakterizacijo razkroja. Rezultati so pokazali, da je bila impregnacija lesa večinoma nezadostna, kar je vodilo v razširjen razkroj, zlasti na območjih, kjer je v les prodrlo premalo biocidnega proizvoda oziroma ni bila prepojena celotna beljava borovih drogov. Pospešen propad drogov je posledica delovanja gliv rjave trohnobe. Raziskava poudarja potrebo po izboljšani impregnaciji in rednem nadzoru drogov za zagotavljanje njihove življenjske dobe in s tem povezano zanesljivostjo oskrbe z električno energijo.
Keywords: daljnovodni drogovi, impregnacija, bakrovi biocidni proizvodi, glivni razkroj, rezistograf, penetracija, retencija
Published in DiRROS: 04.07.2025; Views: 761; Downloads: 313
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1717. Insights into chemopreventive effects of rosmarinic acid against aflatoxin B1-induced genotoxic effectsVeronika Furlan, Matjaž Novak, Martina Štampar, Alja Štern, Bojana Žegura, Urban Bren, 2025, original scientific article Abstract: In this study, the chemopreventive effects of rosmarinic acid (RA), a major phenolic acid of the plant Rosmarinus officinalis L., against the carcinogenic naturally occurring mycotoxin aflatoxin B1 (AFB1) were investigated using both in silico and in vitro approaches. The in silico investigation of the chemical reactions between rosmarinic acid and the carcinogenic metabolite of AFB1, aflatoxin B1 exo-8,9-epoxide (AFBO), was conducted by activation free energies calculations with DFT functionals M11-L and MN12-L, in conjunction with the 6-311++G(d,p) flexible basis set and implicit solvation model density (SMD), according to a newly developed quantum mechanics-based protocol for the evaluation of carcinogen scavenging activity (QM-CSA). Following the computational analyses, the chemoprotective effects of RA were further studied in vitro in human hepatocellular carcinoma HepG2 cells by analyzing its influence on AFB1-induced genotoxicity using a comet assay, γH2AX, and p-H3, while its impact on cell proliferation and cell cycle modulation was assessed using flow cytometry. Our computational results revealed that the activation free energy required for the reaction of RA with AFBO (14.86 kcal/mol) is significantly lower than the activation free energy for the competing reaction of AFBO with guanine (16.88 kcal/mol), which indicates that RA acts as an efficient natural scavenger of AFBO, potentially preventing AFB1-specific DNA adduct formation. The chemoprotective activity of RA was confirmed through in vitro experiments, which demonstrated a statistically significant (p < 0.05) reduction in AFB1-induced single- and double-strand breaks in HepG2 cells exposed to a mixture of AFB1 and RA at non-cytotoxic concentrations. In addition, RA reversed the AFB1-induced reduction in cell proliferation.
Keywords: rosmarinic acid, aflatoxin B1, chemopreventive effects, antigenotoxic effects, density functional theory, chemical carcinogen scavenger, toxicology
Published in DiRROS: 03.07.2025; Views: 504; Downloads: 401
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1718. Biocarbon from olive pomace residue as a sulfur host for carbonate-based lithium-sulfur batteriesFrancisco J. Garcia Soriano, Fernando Cometto, Sofia Raviolo, Tim Šlosar, Elena Tchernychova, Boštjan Genorio, Robert Dominko, Victoria Bracamonte, Alen Vižintin, 2025, original scientific article Published in DiRROS: 03.07.2025; Views: 434; Downloads: 259
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1719. Titanium oxynitride-supported Ru nanoparticles as exceptional electrocatalysts for alkaline hydrogen evolution reactionMilutin Smiljanić, Marjan Bele, Luka Pavko, Armin Hrnjić, Francisco Ruiz-Zepeda, Lazar Bijelić, Ana Rebeka Kamšek, Mejrema Nuhanović, Aleš Marsel, Lea Gašparič, Anton Kokalj, Nejc Hodnik, 2025, original scientific article Published in DiRROS: 03.07.2025; Views: 528; Downloads: 274
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1720. ≠An ≠insight into the diet of the bull ray, Aetomylaeus bovinus (Geoffroy Saint-Hilaire, 1817) in the Northern Adriatic SeaLovrenc Lipej, Riccardo Battistella, Borut Mavrič, Danijel Ivajnšič, 2025, original scientific article Abstract: This study provides baseline information on the feeding habits of the bull ray, Aetomylaeus bovinus (Geoffroy Saint-Hilaire, 1817), in the Gulf of Venezia. Among 1557 prey items isolated from the stomachs of bull ray specimens, gastropods represented the overwhelming majority (93.8%). Within gastropods, Aporrhais pespelecani was the dominant species, followed by Gibbula magus and Bolinus brandaris – all characteristic elements of the biocoenosis of the muddy detritic bottom. We observed differences in prey structure between juveniles and adults, as well as sexes. Among fishes that proved to be particularly important in terms of biomass, the majority of prey items consisted of small pelagic fish, including pilchard (Sardina pilchardus) and horse mackerel (Trachurus sp.). This paper contributes new data on the feeding ecology of a lesser known and critically endangered batoid species.
Keywords: myliobatids, feeding ecology, nursery, Gulf of Venice, batoids, endangered species, marine biology
Published in DiRROS: 03.07.2025; Views: 526; Downloads: 259
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