1. Leiomyosarcoma of the renal vein : analysis of outcome and prognostic factors in the world case series of 67 patientsMarko Novak, Andraž Perhavec, Katherine E. Maturen, Snežana Pavlović Djokić, Simona Jereb, Darja Eržen, 2017, original scientific article Abstract: Background Leiomyosarcoma is a rare malignant mesenchymal tumour. Some cases of leiomyosarcoma of the renal vein (LRV) have been reported in the literature, but no analysis of data and search for prognostic factors have been done so far. The aim of this review was to describe the LRV, to analyse overall survival (OS), local recurrence free survival (LRFS) and distant metastases free survival (DMFS) in LRV world case series and to identify significant predictors of OS, LRFS and DMFS. Methods Cases from the literature based on PubMed search and a case from our institution were included. Results Sixty-seven patients with a mean age of 56.6 years were identified; 76.1% were women. Mean tumour size was 8.9 cm; in 68.7% located on the left side. Tumour thrombus extended into the inferior vena cava lumen in 13.4%. All patients but one underwent surgery (98.5%). After a median follow up of 24 months, the OS was 79.5%. LRFS was 83.5% after a median follow up of 21.5 months and DMFS was 76.1% after a median follow up of 22 months. Factors predictive of OS in univariate analysis were surgical margins, while factors predictive of LRFS were inferior vena cava luminal extension and grade. No factors predictive of DMFS were identified. In multivariate analysis none of the factors were predictive of OS, LRFS and DMFS. Conclusions Based on the literature review and presented case some conclusions can be made. LRV is usually located in the hilum of the kidney. It should be considered in differential diagnosis of renal and retroperitoneal masses, particularly in women over the age 40, on the left side and in the absence of haematuria. Core needle biopsy should be performed. Patients should be managed by sarcoma multidisciplinary team. LRV should be surgically removed, with negative margins.
Keywords: leiomysarcoma, renal vein, surgery, outcomes, prognostic factors
Published in DiRROS: 24.05.2024; Views: 72; Downloads: 57
 Full text (458,38 KB)
This document has many files! More... |
2. |
3. |
4. |
5. Izzivi sodobnih pristopov onkološke zdravstvene nege in zdravljenja : zbornik predavanj2010, proceedings of professional or unreviewed scientific conference contributions Keywords: onkologija, kronične rane, zdravstvena nega, celjenje, bolečina, zdravstvena vzgoja, paliativna oskrba, posvetovanja, zborniki
Published in DiRROS: 04.06.2020; Views: 1762; Downloads: 482
Full text (1,67 MB) |
6. |
7. |
8. |
9. Perioperativni protokol prehrane bolnika z rakom na črevesju pri fast track operacijiNada Rotovnik-Kozjek, Ksenija Mahkovic Hergouth, Patricija Ećimović, Miloš Miloševič, Marko Novak, Erik Brecelj, Boštjan Jovan, Laura Petrica, Robert Terbovšek, Lara Kaligarič, Vesna Ostrožnik, 2007, published professional conference contribution Published in DiRROS: 27.01.2020; Views: 2155; Downloads: 604
Full text (441,83 KB) |
10. Sarkom : klinična potMarko Novak, 2019, professional article Abstract: Za uspeh zdravljenja bolnikov s sarkomi je odločilnega pomena prvo zdravljenje, zato naj tumor ostane nedotaknjen. Ključna je napotitev bolnikov v referenčni center za sarkome, kjer naj potekata tako diagnostika kot zdravljenje. Prvo operacijo naj opravi sarkomski kirurg v referenčnem centru. Onkološki inštitut Ljubljana edini izpolnjuje pogoje za referenčni center za sarkome mehkih tkiv v Sloveniji. Ortopedska klinika Ljubljana je ob sodelovanju z Onkološkim inštitutom Ljubljana referenčni center za zdravljenje bolnikov s sarkomi kosti. Ob odsotni diagnozi rakave bolezni so za sarkom mehkih tkiv na trupu in udih sumljivi tumorji, ki hitro rastejo in/ali bolijo, vsi tumorji pod fascijo, ne glede na velikost in povrhnji tumorji, večji od 5 cm, v retroperitoneju pa tumorji, ki vsebujejo maščobo. Bolniki s tumorjem sumljivim za sarkom mehkih tkiv oziroma potrjenim sarkomom bodo imeli najboljše možnosti, če bodo napoteni na Onkološki inštitut v Ljubljano. V primeru radiološko ugotovljene lezije sumljive za primaren maligen tumor kosti pa, če bodo napoteni na Ortopedsko kliniko v Ljubljano.
Keywords: sarkom, klinične poti, zdravljenje, multidisciplinarni tim
Published in DiRROS: 13.01.2020; Views: 2843; Downloads: 755
Full text (77,83 KB) |
