1401. Unveiling the impact of synthesis routes on water and ethanol sorption performance of ZIF-71 and ZIF-93Ciara Susan Byrne, Katja Vodlan, Connor Hewson, Paul Iacomi, Amalija Golobič, Nataša Zabukovec Logar, 2025, original scientific article Keywords: materials, metallic materials, organic materials, microporosity
Published in DiRROS: 22.08.2025; Views: 477; Downloads: 174
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1403. Performance and stability of PtCo alloy catalysts in high-temperature polymer electrolyte membrane fuel cellsVojtech Domin, Martin Prokop, Tomas Bystron, Matija Gatalo, Luka Pavko, Nejc Hodnik, Bruna Ferreira Gomes, Carlos Manuel Silva Lobo, Carl Eric Hartwig, Christina Roth, Martin Paidar, Karel Bouzek, 2025, original scientific article Published in DiRROS: 22.08.2025; Views: 458; Downloads: 195
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1404. Cytokine release syndrome in non- small cell lung cancer patient receiving immune checkpoint inhibitors : a case reportAna Geltar, Urška Janžič, 2025, original scientific article Abstract: Cytokine release syndrome (CRS) is a well-described immune-related adverse event following chimeric antigen receptor T-cell therapy (CAR-T) but has rarely been reported following therapy with immune checkpoint inhibitors (ICI).
We present a clinical case of severe CRS after ICI therapy for advanced non-small-cell lung cancer (NSCLC). After the third cycle of ipilimumab and nivolumab the patient presented with fever, hypotension and somnolence, leading to acute respiratory failure, acute kidney and hepatic failure, capillary leak syndrome, requiring ICU (intensive care unit) care. She recovered after receiving tocilizumab and steroid therapy.
Subsequently, we found 17 clinical cases of advanced NSCLC patients in peer review, experiencing CRS as an adverse event of treatment with ICI. We review those cases in detail and compare the similarities and outcomes.
Conclusion: CRS is a serious, life-threatening complication that is rare after ICI therapy for solid cancers but becoming increasingly frequent since ICI therapies are broadening indications. When presented with clinical symptoms, considering CRS is crucial, as early recognition is key to timely intervention and favorable outcome for the patient.
Keywords: on-small-cell lung cancer, immune checkpoint inhibitors, cytokine release syndrome, immune- related adverse events, case report
Published in DiRROS: 22.08.2025; Views: 397; Downloads: 203
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1407. European International Centre of Excellence on Sustainable Resource Management in support of the UN Sustainable Development GoalsSnježana Miletić, Meta Dobnikar, 2025, original scientific article Abstract: The sustainable use of mineral resources essential for energy storage, power generation and the transition to climate neutrality is vital. The United Nations Economic Commission for Europe (UNECE) has set the principles and requirements on sustainable resource management needed to accomplish the 2030 Agenda for Sustainable Development and its goals. To support it, the Horizon Europe’s project abbreviated as GSEU is establishing the Geological Service for Europe, of which an integral part will be an EU International Centre of Excellence on Sustainable Resource Management (EU ICE SRM). This capacity building and knowledge centre will operate as a network of partners and experts to assist the decision-makers and key stakeholders in resource management.
Keywords: resource management, sustainable development
Published in DiRROS: 22.08.2025; Views: 366; Downloads: 94
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1408. Impact of mass transport on meniscus electrochemistry determined by time-resolved operando X-ray photoelectron spectroscopyAlenka Križan, Tove Ericson, Laura King, Qianhui Liu, Robert Temperton, Robert Dominko, Ožbej Vodeb, Dušan Strmčnik, Miran Gaberšček, Maria Hahlin, 2025, original scientific article Published in DiRROS: 22.08.2025; Views: 374; Downloads: 161
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1410. Oka-1 manifoldsAntonio Alarcón, Franc Forstnerič, 2025, original scientific article Abstract: In this paper we begin a systematic study of the class of complex manifolds which are universal targets of holomorphic maps from open Riemann surfaces. We call them Oka-1 manifolds, by analogy with Oka manifolds that are universal targets of holomorphic maps from Stein manifolds of arbitrary dimension. We prove that every complex manifold which is dominable at most points by spanning tubes of complex lines in affine spaces is an Oka-1 manifold. In particular, a manifold dominable by ${\mathbb C}^n$ at most points is an Oka-1 manifold. We provide many examples of Oka-1 manifolds among compact complex surfaces, including all Kummer surfaces and all elliptic K3 surfaces. We show that the class of Oka-1 manifolds is invariant under Oka-1 maps inducing a surjective homomorphism of fundamental groups; this includes holomorphic fibre bundles with connected Oka fibres. In another direction, we prove that every bordered Riemann surface admits a holomorphic map with dense image in any connected complex manifold. The analogous result is shown for holomorphic Legendrian immersions in an arbitrary connected complex contact manifold.
Keywords: Riemann surfaces, complex curves, Oka-1 manifolds, Oka manifolds, K3 surfaces
Published in DiRROS: 22.08.2025; Views: 237; Downloads: 122
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