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652. Secondary parkinsonism associated with focal brain lesionsRok Berlot, Anđela Pavlović, Maja Kojović, 2024, review article Abstract: Focal imaging abnormalities in patients with parkinsonism suggest secondary etiology and require a distinctive clinical approach to diagnosis and treatment. We review different entities presenting as secondary parkinsonism associated with structural brain lesions, with emphasis on the clinical course and neuroimaging findings. Secondary parkinsonism may be due to vascular causes, hydrocephalus, space-occupying lesions, metabolic causes (including acquired hepatocerebral degeneration, diabetic uremic encephalopathy, basal ganglia calcifications, osmotic demyelination syndrome), hypoxic-ischaemic brain injury, intoxications (including methanol, carbon monoxide, cyanide, carbon disulfide, manganese poisoning and illicit drugs), infections and immune causes. The onset can vary from acute to chronic. Both uni-and bilateral presentations are possible. Rigidity, bradykinesia and gait abnormalities are more common than rest tremor. Coexisting other movement disorders and additional associated neurological signs may point to the underlying diagnosis. Neuroimaging studies are an essential part in the diagnostic work-up of secondary parkinsonism and may point directly to the underlying etiology. We focus primarily on magnetic resonance imaging to illustrate how structural imaging combined with neurological assessment can lead to diagnosis. It is crucial that typical imaging abnormalities are recognized within the relevant clinical context. Many forms of secondary parkinsonism are reversible with elimination of the specific cause, while some may benefit from symptomatic treatment. This heterogeneous group of acquired disorders has also helped shape our knowledge of Parkinson's disease and basal ganglia pathophysiology, while more recent findings in the field garner support for the network perspective on brain function and neurological disorders.
Keywords: MRI, diagnosis, lesion, parkinsonism, reversible, secondary
Published in DiRROS: 12.11.2025; Views: 161; Downloads: 71
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654. Concentrations of phenolic acids are differently genetically determined in leaves, flowers, and grain of common buckwheat (Fagopyrum esculentum Moench)Alena Vollmannová, Janette Musilová, Judita Lidiková, Július Árvay, Marek Šnirc, Tomáš Tóth, Tatiana Bojňanská, Iveta Čičová, Ivan Kreft, Mateja Germ, 2021, original scientific article Published in DiRROS: 12.11.2025; Views: 136; Downloads: 81
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655. Dietary intake of folate and assessment of the folate deficiency prevalence in Slovenia using serum biomarkersIgor Pravst, Živa Lavriša, Maša Hribar, Hristo Hristov, Naska Kvarantan, Barbara Koroušić-Seljak, Matej Gregorič, Urška Blaznik, Nadan Gregorič, Katja Zaletel, Adrijana Oblak, Joško Osredkar, Katja Žmitek, Anita Kušar, 2021, original scientific article Published in DiRROS: 12.11.2025; Views: 169; Downloads: 95
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656. Inadequate intake of dietary fibre in adolescents, adults, and elderlies : results of Slovenian representative Si. Menu studyBarbara Koroušić-Seljak, Eva Valenčič, Hristo Hristov, Maša Hribar, Živa Lavriša, Anita Kušar, Katja Žmitek, Sanja Krušič, Matej Gregorič, Urška Blaznik, Blaž Ferjančič, Jasna Bertoncelj, Mojca Korošec, Igor Pravst, 2021, original scientific article Published in DiRROS: 12.11.2025; Views: 183; Downloads: 88
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657. Vitamin D intake in slovenian adolescents, adults, and the elderly populationMaša Hribar, Hristo Hristov, Živa Lavriša, Barbara Koroušić-Seljak, Matej Gregorič, Urška Blaznik, Katja Žmitek, Igor Pravst, 2021, original scientific article Published in DiRROS: 12.11.2025; Views: 187; Downloads: 93
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658. Glycoalkaloids in potato : a comprehensive overview of accumulation, detection and mitigation strategiesPeter Dolničar, Lovro Sinkovič, 2025, original scientific article Keywords: potato, α-Chaconine, α-Solanine, analytical methods, detection sensitivity, fod safety
Published in DiRROS: 12.11.2025; Views: 173; Downloads: 75
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659. Dietary intake of trans fatty acids in the Slovenian populationNina Mikec, Maša Hribar, Hristo Hristov, Živa Lavriša, Anita Kušar, Matej Gregorič, Urška Blaznik, Barbara Koroušić-Seljak, Petra Golja, Rajko Vidrih, Katja Žmitek, Igor Pravst, 2021, original scientific article Published in DiRROS: 12.11.2025; Views: 199; Downloads: 84
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