291. |
292. Statins for secondary prevention in women with atherosclerotic vascular disease : a nation-wide analysis of 24,665 women hospitalized for coronary, cerebrovascular or peripheral artery diseaseGregor Verček, Tjaša Furlan, Dalibor Gavrić, Mitja Lainščak, Jerneja Farkaš-Lainščak, Irena Ograjenšek, Petra Došenović Bonča, Borut Jug, 2025, original scientific article Abstract: Background - Statin therapy is recommended for secondary prevention of atherosclerotic vascular disease (ASCVD) based on randomized trials, which enrolled mostly men with coronary artery disease (CAD), whereas women and patients with cerebrovascular (CVD) and peripheral artery disease (PAD) were under-represented. We analyzed the effectiveness of statin therapy uptake in a nation-wide cohort of women hospitalized for ASCVD. Methods - Women hospitalized for CAD, CVD, or PAD, including aortic disease, between 2015 and 2021 were retrospectively identified by linking the national hospital database, medicines reimbursement claims, and national mortality registry. The association of statin uptake within 30 days post-discharge with clinical outcomes (all-cause mortality and cardiovascular hospitalizations) was assessed by Kaplan-Meier curves and Cox proportional hazards regression model with propensity score-derived inverse probability of treatment weights and a 30-day landmark period. Results - We included 24,665 women with ASCVD – 14,419 with CAD, 5,427 with CVD, and 4,819 with PAD. Overall, the median age was 73 (64–81) years. The rates of statin uptake were 50% for women with CAD, 60% for CVD and 28% for PAD. Statin therapy uptake was associated with a reduction in all-cause mortality and cardiovascular hospitalizations across all three major types of ASCVD: hazard ratio (HR) 0.88, 95% confidence interval (CI) 0.83 – 0.93, p=0.001 for CAD, HR 0.87, 95% CI 0.80 – 0.94, p=0.006 for PAD, and HR 0.72, 95% CI 0.66 – 0.78, p<0.001 for CVD. Conclusion -Statin therapy is associated with reduced all-cause mortality and cardiovascular hospital readmissions in women with all major types of ASCVD.
Keywords: health, diseases, prevention
Published in DiRROS: 28.11.2025; Views: 157; Downloads: 76
 Full text (1,74 MB)
This document has many files! More... |
293. Temporal variability in the incidence and risk factors for pharyngocutaneous fistula development after total laryngectomyRobert Šifrer, Maja Dolenc-Novak, Sara Bitenc, Simon Fugina, Luka Jesenko, Primož Strojan, 2024, original scientific article Abstract: The pharyngocutaneous fistula (PCF) is a pathologic canal connecting the pharyngeal lumen with the skin of the neck occurring after a total laryngectomy (TLE), the removal of the entire larynx. The incidence of PCF ranges from 0% to 80%. Our study aimed to identify the temporal changes in PCF incidence over an extended period and determine the risk factors for increases in the PCF rate. By reviewing patient data from 2004 to 2022, we discovered a total incidence of 26.7%. This study revealed four high-incidence periods, averaging 37.61%, each followed by lower-incidence periods of 19.38%. The surgical wound infection and a history of head and neck cancer along with its related treatments were identified as independent risk factors during most of the high-incidence periods. The continuous monitoring of patients following TLE can assist providers in the better prediction and, consequently, timely management of PCF, ultimately improving patient outcomes after TLE.
Published in DiRROS: 28.11.2025; Views: 158; Downloads: 70
Full text (347,88 KB)
This document has many files! More... |
294. Dataset of xylem and phloem traits of Fraxinus ornus, Quercus pubescens and Ostrya carpinifolia from Podgorski Kras (Slovenia) in the period 2019-2021Jožica Gričar, Klemen Eler, Saša Ogorevc, Debojit Chanda, Sarkiri Kro, Mohendra Thapa, Polona Hafner, Peter Prislan, 2025, complete scientific database of research data Keywords: raziskovalni podatki
Published in DiRROS: 28.11.2025; Views: 193; Downloads: 30
 Full text (177,04 KB)
This document has many files! More... |
295. |
296. |
297. |
298. |
299. Iterative construction of conserved quantities in dissipative nearly integrable systemsIris Ulčakar, Zala Lenarčič, 2024, original scientific article Abstract: Integrable systems offer rare examples of solvable many-body problems in the quantum world. Because of the fine-tuned structure, their realization in nature and experiment is never completely accurate, and therefore effects of integrability are observed only transiently. One way to overcome this limitation is to weakly couple nearly integrable systems to baths and driving: this will stabilize integrable effects up to arbitrary time and encode them in the stationary state approximated by a generalized Gibbs ensemble. However, the description of such driven dissipative nearly integrable models is challenging and no exact analytical methods have been proposed so far. Here, we develop an iterative scheme in which integrability breaking perturbations (baths) determine the conserved quantities that play the leading role in a highly efficient truncated generalized Gibbs ensemble description. Our scheme paves the way for easier calculations in thermodynamically large systems and can be used to construct unknown conserved quantities.
Published in DiRROS: 28.11.2025; Views: 99; Downloads: 40
Full text (671,13 KB) |
300. The influence of health claims and nutritional composition on consumers' yoghurt preferencesKrista Miklavec, Igor Pravst, Klaus G. Grunert, Marija Klopčič, Jurij Pohar, 2015, original scientific article Keywords: health claims, biotin, probiotics, conjoint analysis, cluster analysis
Published in DiRROS: 28.11.2025; Views: 171; Downloads: 82
Full text (800,16 KB)
This document has many files! More... |
