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21 - 30 / 2000
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21.
ESR essentials: juvenile idiopathic arthritis : what every radiologist needs to know: practice recommendations by the European Society of Paediatric Radiology
Sílvia Costa Dias, Celine Habre, Pier Luigi Di Paolo, Paola d’Angelo, Thomas A. Augdal, Oskar W. Angenete, Damjana Ključevšek, 2025, review article

Abstract: Juvenile Idiopathic Arthritis (JIA) is a major contributor to chronic diseases, affecting around 1–2 in 1000 children under the age of 16. With modern treatments, the morbidity has been reduced; however, there is increasing evidence that many, if not most, children with JIA will have a chronic disease with ongoing activity into adulthood. Many studies discuss the possibility of an early window of opportunity in which patients have the best chance of responding to therapy, thereby underscoring the importance of timely and appropriate imaging. Children typically present at 4–5 years of age with one or more stiff and painful joints. If JIA is suspected, the child should undergo an ultrasound of the involved joint(s), performed by a radiologist with experience in paediatric imaging. If this is normal, with no abnormal laboratory tests and low clinical suspicion of JIA, no further imaging is required. If there is inconsistency between ultrasound and clinical findings, then they should proceed to MRI, including intravenous contrast, of the involved joint. Additional radiographs, or low-dose CT for the axial joints to examine for potential destructive change, deformation, or growth abnormalities, should be considered. In children presenting with monoarthritis, bacterial infection must be ruled out.
Keywords: child, arthritis, juvenile, diagnostic imaging, ultrasonography, magnetic resonance imaging
Published in DiRROS: 19.12.2025; Views: 5; Downloads: 6
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22.
Duhovna oskrba v vojski v času pospešene digitalizacije, tehnološkega napredka in družbenih prelomov
Gašper Pirc, 2025, original scientific article

Abstract: V pričujočem prispevku raziskujem koncept duhovne oskrbe v sodobni druž-bi. Na podlagi številnih teoretskih in empiričnih raziskav ter sociološkega in reli-giološkega pristopa prikažem, da se duhovna oskrba zlasti v zahodni kulturno-po-litični kulturi vse bolj premika od tradicionalnih, pastoralnih modelov duhovne oskrbe, strogo povezanih z načinom dela lokalno prevladujočih religioznih insti-tucij, k pluralnim, medreligioznim in humanistično-sekularnim oblikam duhovne podpore.V članku obravnavam vpliv razvoja avtonomnih orožij in informacijskega preporoda, ki vsaj posredno vplivata na razvoj novih oblik dehumanizacije in primerov masovnega uničenja, na pripadnike vojske ter analiziram, kako se (tako religiozne kot humanistične) oblike duhovne oskrbe odzivajo na te spremembe. poseben poudarek podajam pojmu moralne poškodbe, ki je v nedavni religiolo-ški in psihološki literaturi požel precej zanimanja, tehnološki procesi sodobnosti in družbeno-politične spremembe pa morda še povečujejo pojavnost tovrstnih travm. V članku nakazujem, da je duhovna oskrba eno redkih polj, kjer se v času pospešenega razvoja umetne inteligence in avtonomnih orožij še ohranja prostor za neposreden človeški stik in etično refleksijo. To še posebej omogoča razumevanje duhovne oskrbe kot celostne humanistične skrbi za duhovnost člo-veškega bitja, ki ne pozna strogega ločevanja na podlagi geografskih, religioznih in vrednostno-normativnih meja.
Keywords: duhovna oskrba, vojno kaplanstvo, avtonomno orožje, digitalna humanistika, etika vojne, vojska in duhovnost
Published in DiRROS: 19.12.2025; Views: 9; Downloads: 7
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23.
Hazard identification and characterization of leachable chemicals from plastic products – a new PARC project
Hubert Dirven, Nina Franko, Marija Sollner Dolenc, Tim Ravnjak, Martina Štampar, Bojana Žegura, 2025, review article

Abstract: A recent study has suggested that plastics may contain more than 16,000 chemicals, including additives, processing aids, starting substances, intermediates and Non-Intentionally Added Substances. Plastic chemicals are released throughout the plastic life cycle, from production, use, disposal and recycling. Most of these chemicals have not been studied for potential hazardous properties for humans and in the environment. To refine the risk assessment of these leachable chemicals, additional hazard data are needed. The PlasticLeach project within the EU co-funded Partnership for the Assessment of Risks from Chemicals (PARC) aims to address this data gap by screening several plastic products in daily use. Leachates will be prepared from a number of these plastic items, and these chemical mixtures will be further tested using several test guideline compliant assays and New Approach Methodologies covering both human health and environmental endpoints. The most toxic leachates will be characterized using a non-targeted analysis pipeline to identify chemicals in the leachate. When single chemicals of concern are identified, these will be further tested to determine hazardous properties and identify the respective potency factors to better understand their specific hazard profiles. A tiered approach for hazard testing will be followed. The experimental work will be complemented by in silico toxicological profiling, using publicly available toxicity databases and tools, including Artificial Intelligence tools that cover both human and environmental endpoints. A comprehensive array of endpoints, including cytotoxicity, endocrine disruption, genotoxicity, immunotoxicity, reproductive toxicity and effects related to ecotoxicity will be evaluated. In this paper, we outline the plastic products to be tested and the battery of assays that will be used to identify hazards relevant to both human health and the environment. Data generated from in silico, in vitro, and in vivo approaches will be reported using standardized formats, stored within a centralized repository, and harmonized to adhere to the FAIR data principles (Findable, Accessible, Interoperable, and Reusable). This integrated strategy will not only advance our understanding of the risks associated with plastic-derived chemicals but will also provide critical support for regulatory decision-making and facilitate the development of safer, and more ecofriendly plastic materials in the future.
Keywords: plastics, chemicals, leachables, PARC, new approach methodologies, hazard assessment, toxicity, risk assessment
Published in DiRROS: 19.12.2025; Views: 16; Downloads: 13
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24.
Vibration-induced freezing in Aegorhinus nodipennis (Coleoptera: Curculionidae) : implications for pest management in hazelnuts
Nataša Stritih Peljhan, Alenka Žunič Kosi, Andres Eduardo Quiroz Cortez, Patricia D. Navarro, María José Lisperguer F., Tommaso De Gregorio, Matteo Maspero, 2025, original scientific article

Abstract: The weevil Aegorhinus nodipennis (Coleoptera: Curculionidae) (Hope, 1834) is a polyphagous woodboring beetle of economic concern in Chile and southern Argentina, mainly affecting berries and hazelnut. Although insecticides may be applied in hazelnut orchards, their effectiveness is limited and can be environmentally impactful, underscoring the need for alternative, sustainable control strategies. Attempts to exploit semiochemicals for attraction or repellence have yielded only modest results, failing to support effective trapping or deterrence. This study investigates substrate-borne vibrations as a complementary behavioral management tool by examining their potential to induce defensive responses in A. nodipennis. We demonstrate that walking individuals exhibit a stereotyped freezing response to vibrational stimuli, with peak sensitivity at 50 to 150 Hz (median threshold at 0.71 m/s2) and a secondary sensitivity increase at 1–2 kHz. The duration of the immobile phase increases strongly with stimulus duration, with a median around 200 s following a 5 s stimulus, but is much less affected by amplitude once the threshold is exceeded. In addition, weevils exhibit a marked postfreeze locomotor suppression, with walking speed reduced to 25% to 30% of prestimulus levels. These findings suggest that extended low-amplitude vibrational stimuli could effectively suppress activity and feeding. This offers a novel, nonchemical, and potentially economically viable approach in managing this pest. Deterrent vibrations could be deployed directly on host plants or on structural barriers in orchards. This study provides a foundation for integrating vibrational cues into pest management frameworks for A. nodipennis and related weevils, though results are currently limited to females.
Keywords: substrate-borne vibration, locomotor suppression, vibrational deterrence, applied biotremology
Published in DiRROS: 19.12.2025; Views: 10; Downloads: 13
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26.
Slippery slopes : montane isolation and elevational shifts shape the evolution and diversity of Iberolacerta lizards
Christophe Dufresnes, Sven Gippner, Sylvia Hofmann, Spartak Litvinchuk, Anamarija Žagar, Daniel Jablonski, Gilles Pottier, Rodrigo Megía-Palma, Gregorio Sánchez-Montes, Octavio Jiménez Robles, Enrique Ayllón, 2026, original scientific article

Abstract: Understanding the processes driving the diversity of mountain herpetofauna requires a comprehensive examination of species diversification across evolutionary scales. Here, we investigate the phylogeography of Iberolacerta, a genus of eight lizard species mainly restricted to high elevations in southwestern Europe. Using genomic data, we reconstructed a nuclear phylogeny that aligns with mitochondrial evidence in supporting the divergence of all currently recognized species. Notably, we detect historical nuclear gene flow between I. cyreni and I. martinezricai in Central Spain, suggesting past range overlap, reminiscent of previously observed mitochondrial introgression between I. galani and I. monticola, and the lack of divergence between disjoint populations of I. monticola. Bioclimatic projections accordingly depict broader historical ranges during the last glacial maximum compared to interglacial and current conditions. At the intraspecific level, genomic analyses of four high-elevation species reveal that genetic structure is mainly shaped by isolation-by-distance and, in I. cyreni, by separation among mountain ranges, while heterozygosity generally decreases with elevation. These findings are consistent with the impact of glacial-interglacial cycles on the genetic diversity of montane taxa: populations experience genetic isolation and altitudinal bottlenecks during interglacial periods, but are reconnected and admix in lowland areas during glacial periods. These processes are expected to leave contrasting signatures between the mitochondrial and nuclear genomes, as well as between slow- and fast-evolving molecular markers. From a conservation perspective, our results highlight that the genetically richest – and potentially most adaptive – populations occur at the lowland edges of the species’ ranges, where they are also most vulnerable to climate change.
Keywords: biogeography, climate change, Lacertidae, RAD-seq, Europe
Published in DiRROS: 19.12.2025; Views: 8; Downloads: 10
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27.
Oblikovanje in začetna validacija lestvice obnovitvene zmožnosti urbanih okolij : izsledki s Filipinov
Zaldy F. Corpuz, 2025, original scientific article

Abstract: Urbana okolja vplivajo na psihično počutje ljudi, večina lestvic za merjenje tega vpliva pa je bila do zdaj oblikovana samo za naravna okolja. V članku sta predstavljena oblikovanje in začetna validacija lestvice za merjenje obnovitvene zmožnosti urbanih okolij – oblikovalsko usmerjenega merskega orodja, namenjenega urbanim prostorom, ki jih ljudje vsak dan uporabljajo. Nabor 25 postavk, izbranih na podlagi teorij obnove pozornosti in zmanjšanja stresa, je bil preizkušen s 1.001 prebivalcem filipinskega mesta Urdaneta. S potrditveno faktorsko analizo je bila izbrana končna struktura lestvice z visoko stopnjo prileganja in zanesljivosti, ki je vključevala 17 postavk in štiri faktorje (kakovost, funkcionalnost, privlačnost in sprostitev), združenih v faktor drugega reda, imenovanega obnovitvena zmožnost urbanih okolij. Konvergentna veljavnost je bila dosežena, korelacije med faktorji so bile močne in hkrati skladne s konstruktom višjega reda. Faktor drugega reda se je izkazal za močnega napovednika splošnega zadovoljstva z urbanim prostorom, ki ga je posamezni udeleženec v raziskavi ocenjeval na podlagi fotografije. Večskupinski modeli so pokazali odvisnost faktorjev od tipa urbanega prostora: kakovost je bila najpomembnejši faktor na območjih, namenjenih rekreaciji, privlačnost na stanovanjskih območjih, območjih javnih ustanov, ulicah in trgovskih območjih, funkcionalnost na potniških terminalih, sprostitev pa je bila pomemben, a ne najbolj vpliven faktor na vseh urbanih prostorih. Izsledki raziskave so prečne narave, zato med njimi ni mogoče opredeliti zanesljivih vzročnih povezav. Lestvica je praktično diagnostično orodje za pripravo oblikovalskih hipotez, hkrati pa kaže, da se to, kar deluje obnovitveno ali blagodejno za počutje ljudi, razlikuje glede na tip urbanega prostora.
Keywords: obnovitvena okolja, tipi urbanih prostorov, psihometrična validacija, merska invariantnost, okoljska psihologija
Published in DiRROS: 19.12.2025; Views: 11; Downloads: 6
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28.
Modernistična arhitektura kot del sodobne identitete mest : Plečnik in Ravnikar v Ljubljani ter Grabrijan in Neidhardt v Sarajevu
Nermina Zagora, Sabina Mujkić, Lejla Kahrović-Handžić, Edib Pašić, 2025, original scientific article

Abstract: V članku je proučen vpliv modernistične arhitekture na oblikovanje identitete dveh mest nekdanje Jugoslavije, Ljubljane in Sarajeva. Primerjani so prispevki ključnih arhitektov k oblikovanju urbanih tkiv in identitet obeh mest v 20. stoletju, pri čemer sta upoštevana njuna skupna socialistična preteklost in njun različni družbenokulturni razvoj po koncu devetdesetih let 20. stoletja. Modernistična dediščina analiziranih mest je obravnavana z vidika trajnostnosti, odpornosti in spreminjajočega se pojmovanja kulturne identitete. Poseben poudarek je na delih Jožeta Plečnika in Edvarda Ravnikarja v Ljubljani ter Dušana Grabrijana in Juraja Neidhardta v Sarajevu.
Keywords: identiteta mesta, kontekst, dediščina, zapuščina, urbanizem po meri človeka, Jože Plečnik, Edvard Ravnikar, Dušan Grabrijan, Juraj Neidhardt
Published in DiRROS: 19.12.2025; Views: 6; Downloads: 6
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29.
Are caves enough to represent karst groundwater biodiversity? Insights from geospatial analyses applied to European obligate groundwater-dwelling copepods
Emma Galmarini, Mattia Di Cicco, Barbara Fiasca, Nataša Mori, Mattia Iannella, Tiziana Di Lorenzo, Francesco Cerasoli, Diana Maria Paola Galassi, 2025, original scientific article

Abstract: Caves are recognized as biodiversity hotspots for groundwater fauna, including obligate groundwater-dwelling copepods (Crustacea: Copepoda), exhibiting high species richness, endemism, and phylogenetic rarity. However, the extent to which caves alone provide a representative estimate of copepod species richness in karst areas remains uncertain. Taking advantage of the recently published EGCop dataset, the first expert-validated, Europe-wide occurrence dataset for obligate groundwater-dwelling copepods (hereinafter, GW copepods), this study investigates the distribution of GW copepods into karst areas, comparing species richness in caves versus other karst groundwater habitats (e.g., springs, karst streams, artificial wells), within and among the European karst units. The main aims are: (i) identifying karst areas which represent hotpots of GW copepod species richness; (ii) assessing to which extent caves, as open windows to the subterranean environments, contribute to define hotspots of GW copepods’ species richness into karst areas across Europe. EGCop comprises 6,986 records from 588 copepod species/subspecies distributed among four orders: Cyclopoida (3,664 records, 184 species), Harpacticoida (3,288 records, 395 species), Calanoida (32 records, seven species), and Gelyelloida (two records, two species). To perform geospatial analyses, we filtered the dataset by: (i) selecting only the records with spatial uncertainty in the associated coordinates lower than 10 km; (ii) searching for those records falling within, or very close to, the polygons representing European karst areas. Species richness hotspots were then estimated through geospatial analyses in geographic information system (GIS) environment. Within the selected records, those specifically referring to karst habitats (2,526 records, 369 species) are primarily represented by Harpacticoida (1,199 records, 228 species) and Cyclopoida (1,293 records, 132 species). Among species collected from karst habitats, records from caves (1,867, 73.9%) belong to 318 species (Harpacticoida = 189, Cyclopoida = 122, Calanoida = 7), representing 86.1% of the total species richness of karst habitats. Geospatial analyses reveal that the European hotspots of GW copepods’ species richness recorded exclusively in caves reflect the spatial arrangement of postglacial refugia in southern karst regions, though representing a subset of the broader diversity found across all karst groundwater habitats. Our findings highlight that the contribution of cave systems in groundwater biodiversity assessments and related conservation planning may vary depending on the evolution and morphologies of the target karst regions—often pointing to a high representativeness of caves for subterranean biodiversity, sometimes revealing their lower explanatory power within the broader karst systems.
Keywords: copepoda, groundwater, biodiversity, datasets, caves, karst, Europe
Published in DiRROS: 19.12.2025; Views: 6; Downloads: 11
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