1131. Evaluating plant growth–defense trade-offs by modelingthe interaction between primary and secondary metabolismJan Zrimec, Sandra Correo, Maja Zagorščak, Marko Petek, Carissa Bleker, Katja Stare, Christian Schuy, Sophia Sonnewald, Kristina Gruden, Zoran Nikoloski, 2025, original scientific article Abstract: Understanding the molecular mechanisms behind plant response to stress can enhancebreeding strategies and help us design crop varieties with improved stress tolerance,yield, and quality. To investigate resource redistribution from growth- to defense-relatedprocesses in an essential tuber crop, potato, here we generate a large-scale compartmen-talized genome-scale metabolic model (GEM), potato-GEM. Apart from a large-scalereconstruction of primary metabolism, the model includes the full known potato sec-ondary metabolism, spanning over 566 reactions that facilitate the biosynthesis of 182distinct potato secondary metabolites. Constraint-based modeling identifies that theactivation of the largest amount of secondary (defense) pathways occurs at a decreaseof the relative growth rate of potato leaf, due to the costs incurred by defense. We thenobtain transcriptomics data from experiments exposing potato leaves to two bioticstress scenarios, a herbivore and a viral pathogen, and apply them as constraints toproduce condition-specific models. We show that these models recapitulate experimen-tally observed decreases in relative growth rates under treatment as well as changes inmetabolite levels between treatments, enabling us to pinpoint the metabolic rewiringunderlying growth–defense trade-offs. Potato- GEM thus presents a useful resource tostudy and broaden our understanding of potato and general plant defense responsesunder stress conditions.
Keywords: systems biology, constraint-based metabolic modeling, growth-defence trade-offs, secondary metabolism
Published in DiRROS: 24.09.2025; Views: 376; Downloads: 148
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1132. An energy community as a platform for local sector coupling : From complex modelling to simulation and implementationEdvard Košnjek, Boris Sučić, D. Kostić, Tom Smolej, 2024, original scientific article Abstract: his paper presents the reference architecture of a model for sustainable local planning and sector coupling based on an energy-community framework. The proposed approach includes four building blocks: (1) the data-acquisition building block - local energy consumption, (2) the building block for modelling and calculations - local energy conversions, (3) the building block for connecting the infrastructure status and needs with development plans of the energy-network operators and aggregators, and (4) the decision-support building block for local environmental, spatial and energy planning. The proposed approach was tested in a real industrial environment and a local community. Initial simulation results confirmed that excess heat from the energy-intensive company has the potential to replace the natural gas that is currently used for the production of heat in a local district-heating system. The natural gas savings in the district-heating system would be 3,299,676 Nm3, as the excess heat could cover as much as 68.4 % of the required heat for the local community. It has also been proven that complex modelling and simulation of a future sustainable solution can contribute to its optimization, understanding, and acceptance by all stakeholders and thereby increase the potential of the project's implementation.
Published in DiRROS: 24.09.2025; Views: 344; Downloads: 84
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1133. The toll walk transit function of a graph: axiomatic characterizations and first-order non-definabilityManoj Changat, Jeny Jacob, Lekshmi Kamal K. Sheela, Iztok Peterin, 2026, original scientific article Abstract: A walk $W=w_1w_2\dots w_k$, $k\geq 2$, is called a toll walk if $w_1\neq w_k$ and $w_2(w_{k-1})$ are the only neighbors of $w_1(w_k)$ on $W$ in a graph $G$. A toll walk interval $T(u,v)$, $u,v\in V(G)$, contains all the vertices that belong to a toll walk between $u$ and $v$. The toll walk intervals yield a toll walk transit function $T:V(G)\times V(G)\rightarrow 2^{V(G)}$. We represent several axioms that characterize the toll walk transit function among chordal graphs, trees, asteroidal triple-free graphs, Ptolemaic graphs, and distance hereditary graphs. We also show that the toll walk transit function can not be described in the language of first-order logic for an arbitrary graph.
Keywords: toll walk, transit function, axioms, chordal graphs, AT-free graphs, Ptolemaic graphs, distance-hereditary graphs
Published in DiRROS: 24.09.2025; Views: 240; Downloads: 119
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1137. Raziskovanje v vzgoji in izobraževanju : digitalizacija vzgoje in izobraževanja - priložnosti in pasti2023, scientific monograph Abstract: Pričujoča monografija z naslovom »Raziskovanje v vzgoji in izobraževanju: Digitalizacija vzgoje in izobraževanja – priložnosti in pasti« se osredotoča na kompleksne spremembe, ki jih prinaša digitalizacija ter vključevanje digitalnih tehnologij v izobraževalne procese, ter ponuja različne razmisleke ter poglede na ta proces, saj razčlenjuje večplastne razsežnosti te spremembe in preučuje zapleteno mrežo politik, ki jo podpirajo. Sestavljena je iz dveh delov, od katerih je vsak posvečen samostojnemu, a kljub temu prepletenemu vidiku te digitalne preobrazbe.
Keywords: digitalna tehnologija, digitalizacija v izobraževanju
Published in DiRROS: 24.09.2025; Views: 365; Downloads: 180
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1138. Pedagoški leksikon : izbrani temeljni pojmi2023, dictionary, encyclopaedia, lexicon, manual, atlas, map Abstract: Elektronska publikacija vsebuje poskusni izbor gesel s področja pedagogike, ki predstavljajo podlago in konceptualni okvir za dolgoročni projekt, v katerem se povezujeta leksikografska veda ter raziskovalno področje vzgoje in izobraževanja. Glavni namen tovrstnega povezovanja je zasnova dinamične, kontinuirano izhajajoče elektronske publikacije – tematskega leksikona, ki temelji na akademskih standardih pisanja in z avtorskimi geselskimi članki o temeljnih pojmih s področja vzgoje in izobraževanja predstavlja referenčno delo na omenjenem področju v slovenskem jeziku.
Published in DiRROS: 24.09.2025; Views: 311; Downloads: 130
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1139. Empowering teachers across Europe to deal with social, emotional and diversity-related challenges : Policy perspectives2024, scientific monograph Keywords: vzgoja in izobraževanje, učitelji, opolnomočenje učiteljiev, socialni izzivi, čustveni izzivi, raznolikost, Evropa, politične perspektive, psihologija
Published in DiRROS: 24.09.2025; Views: 308; Downloads: 140
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