1. Poročilo o preskusu št.: LVG 2024-057 : vzorec št. 2024/00240Barbara Piškur, Špela Hočevar, Zina Devetak, 2024, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, program preiskav, Fusarium circinatum, Pinus, borov smolasti rak, PCR
Published in DiRROS: 24.06.2024; Views: 40; Downloads: 0
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2. Poročilo o preskusu št.: LVG 2024-053 : vzorec št. 2024/00116Tine Hauptman, Zina Devetak, Špela Hočevar, Barbara Piškur, 2024, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, Geosmithia morbida, bolezen tisočerih rakov, vektorji, rtPCR
Published in DiRROS: 19.06.2024; Views: 105; Downloads: 0
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3. Poročilo o preskusu št.: LVG 2024-051 : vzorec št. 2024/00087Tine Hauptman, Špela Hočevar, Barbara Piškur, 2024, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, Euwallacea fornicatus, Neocosmospora euwallaceae, strokovne naloge IVHVVR, molekularne analize
Published in DiRROS: 19.06.2024; Views: 98; Downloads: 2
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4. Poročilo o preskusu št.: LVG 2024-049 : vzorec št. 2024/00114Tine Hauptman, Zina Devetak, Špela Hočevar, Barbara Piškur, 2024, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, hrošči, ličinke, hlodovina, molekularne analize, strokovne naloge IVHVVR
Published in DiRROS: 19.06.2024; Views: 105; Downloads: 0
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5. Poročilo o preskusu št.: LVG 2024-048 : vzorec št. 2024/00122Tine Hauptman, Špela Hočevar, Barbara Piškur, 2024, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, Fusarium circinatum, Pinus, borov smolasti rak, rtPCR
Published in DiRROS: 19.06.2024; Views: 106; Downloads: 0
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7. New insights in ATP synthesis as therapeutic target in cancer and angiogenic ocular diseasesCornelis J. F. van Noorden, Bahar Yetkin-Arik, Paola Serrano Martinez, Noëlle Bakker, Mathilda E. van Breest Smallenburg, Reinier O. Schlingemann, Ingeborg Klaassen, Bernarda Majc, Anamarija Habič, Urban Bogataj, Katrin S. Galun, Miloš Vittori, Mateja Erdani-Kreft, Metka Novak, Barbara Breznik, Vashendriya V. V. Hira, 2024, review article Abstract: Lactate and ATP formation by aerobic glycolysis, the Warburg effect, is considered a hallmark of cancer. During angiogenesis in non-cancerous tissue, proliferating stalk endothelial cells (ECs) also produce lactate and ATP by aerobic glycolysis. In fact, all proliferating cells, both non-cancer and cancer cells, need lactate for the biosynthesis of building blocks for cell growth and tissue expansion. Moreover, both non-proliferating cancer stem cells in tumors and leader tip ECs during angiogenesis rely on glycolysis for pyruvate production, which is used for ATP synthesis in mitochondria through oxidative phosphorylation (OXPHOS). Therefore, aerobic glycolysis is not a specific hallmark of cancer but rather a hallmark of proliferating cells and limits its utility in cancer therapy. However, local treatment of angiogenic eye conditions with inhibitors of glycolysis may be a safe therapeutic option that warrants experimental investigation. Most types of cells in the eye such as photoreceptors and pericytes use OXPHOS for ATP production, whereas proliferating angiogenic stalk ECs rely on glycolysis for lactate and ATP production.
Keywords: aerobic glycolysis, anaerobic glycolysis, angiogenesis, ATP synthesis, cancer cells, cancer stem cells, endothelial cells, energy metabolism, eye diseases, oxidative phosphorylation, pericytes, retina, Warburg effect
Published in DiRROS: 18.06.2024; Views: 91; Downloads: 63
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9. Localization patterns of cathepsins K and X and their predictive value in glioblastomaBarbara Breznik, Clara Limbaeck Stanic, Andrej Porčnik, Andrej Blejec, Miha Koprivnikar Krajnc, Roman Bošnjak, Janko Kos, Cornelis J. F. van Noorden, Tamara Lah Turnšek, 2018, original scientific article Keywords: cathepsins, glioblastoma, immunohistochemistry, patient survival, cancer stem cell niches
Published in DiRROS: 11.06.2024; Views: 64; Downloads: 18
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