| Naslov: | Influence of adipose-derived stromal vascular fraction on resorption of a large-volume free-fat transplant evaluated using T3D optical scanning |
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| Avtorji: | ID Koren, Matic (Avtor)
ID Kranjc Brezar, Simona (Avtor)
ID Dovšak, Tadej (Avtor)
ID Serša, Gregor (Avtor)
ID Kansky, Andrej (Avtor)
ID Ihan Hren, Nataša (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (1,16 MB)
MD5: 1240545A213DD262D51AF7EE97EC2AD7
 URL - Izvorni URL, za dostop obiščite https://www.mdpi.com/2076-3417/13/12/7100/pdf
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
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| Povzetek: | Background and Objectives: The main drawback of lipofilling is fat transplant volume loss, which makes long-term results unreliable. This study’s aim was to assess the influence of an adiposederived stromal vascular fraction (SVF) on volume retention in large-volume fat grafts. Materials and Methods: A murine model was used for the in vivo evaluation of fat-graft volume changes over 6 months. We used 28 immunocompromised nude NU(NCr)-Foxn1nu mice and human fat tissue as a liposuction by-product. Part of the fat tissue was used for SVF preparation. We created a fat transplant without SVF (SVF-) and with SVF (SVF+) groups. Large-volume grafts were injected above the sacrum and scapula in the same animal. Volume loss was evaluated using three-dimensional optical scanning at 14 days (T1), 3 months (T2), and 6 months (T3) after transplantation. Scans were processed with Artec Studio software to obtain stereolithography files. The volumes were calculated in RapidForm software 2006. Results: The highest volume loss was observed above the scapula at T3 (SVF- 85%; SVF+ 75%). There was a significant difference in volume between SVF-/SVF+ for grafts above the sacrum at T2, with lower loss in SVF+, and the significance became stronger at T3. The difference in volume loss was also significant above the scapula between SVF-/SVF+ at T3. Conclusions: Although we found a beneficial effect of SVF on the long-term survival of large-volume fat tissue transplants, volume loss due to other contributing factors was high. |
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| Ključne besede: | lipofilling, murine model, stromal vascular fraction |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Leto izida: | 2023 |
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| Št. strani: | str. 7100-1-7100-11 |
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| Številčenje: | Vol. 13, no. 12 |
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| PID: | 20.500.12556/DiRROS-31511  |
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| UDK: | 602 |
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| ISSN pri članku: | 2076-3417 |
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| DOI: | 10.3390/app13127100 |
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| COBISS.SI-ID: | 155712515 |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 15. 6. 2023;
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| Datum objave v DiRROS: | 04.08.2026 |
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| Število ogledov: | 41 |
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| Število prenosov: | 30 |
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| Metapodatki: |    |
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