| Naslov: | Advancements in uterine sarcoma management : a review |
|---|
| Avtorji: | ID Lebar, Vojka (Avtor)
ID Čelebić, Aleksandar (Avtor)
ID Calleja-Agius, Jean (Avtor)
ID Jakimovska, Marina (Avtor)
ID Drusany Starič, Kristina (Avtor) |
|---|
| Datoteke: |  PDF - Predstavitvena datoteka, prenos (501,02 KB)
MD5: 102C26614D75E86DECBE776C2DF6DBA9
 URL - Izvorni URL, za dostop obiščite https://www.sciencedirect.com/science/article/pii/S0748798325000745?via%3Dihub
|
|---|
| Jezik: | Angleški jezik |
|---|
| Tipologija: | 1.02 - Pregledni znanstveni članek |
|---|
| Organizacija: |  UKC LJ - Univerzitetni klinični center Ljubljana
|
|---|
| Povzetek: | Uterine sarcomas are rare, accounting for 3–7% of uterine malignancies. This review aims to summarize advancements in diagnostics and treatment over the last decade, focusing on innovative imaging techniques, molecular diagnostics, and treatment modalities. Recent diagnostic advancements include enhanced imaging techniques such as MRI and AI-driven algorithms, improving accuracy in differentiating between benign and malignant uterine tumors. Biomarkers like lactate dehydrogenase (LDH) and microRNAs have shown potential in preoperative identification. Treatment strategies continue to evolve, with surgical resection being the cornerstone. The role of lymphadenectomy and adnexectomy varies by histopathological subtype, emphasizing personalized approaches. Adjuvant therapies remain controversial, tailored to patient risk factors and tumor characteristics. Fertility-sparing options are viable for selected patients, though not recommended for high-grade tumors. Significant progress in diagnostic techniques and personalized treatment approaches has improved the management of uterine sarcomas. Future guidelines from major oncology groups are expected to standardize care. Continued research is essential for refining treatment protocols and enhancing patient outcomes. |
|---|
| Ključne besede: | uterine sarcomas, molecular diagnostics, artificial intelligence, treatment approache |
|---|
| Status publikacije: | Objavljeno |
|---|
| Verzija publikacije: | Objavljena publikacija |
|---|
| Leto izida: | 2025 |
|---|
| Št. strani: | str. 1-6 |
|---|
| Številčenje: | Vol. 51, iss. 4, [article no.] 109646 |
|---|
| PID: | 20.500.12556/DiRROS-27719  |
|---|
| UDK: | 616-006 |
|---|
| ISSN pri članku: | 1532-2157 |
|---|
| DOI: | 10.1016/j.ejso.2025.109646 |
|---|
| COBISS.SI-ID: | 232012035 |
|---|
| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 9. 4. 2025;
|
|---|
| Datum objave v DiRROS: | 23.02.2026 |
|---|
| Število ogledov: | 162 |
|---|
| Število prenosov: | 71 |
|---|
| Metapodatki: |    |
|---|
|
:
|
Kopiraj citat |
|---|
| | | | Objavi na: |  |
|---|
Postavite miškin kazalec na naslov za izpis povzetka. Klik na naslov izpiše
podrobnosti ali sproži prenos. |
