| Naslov: | Interpreting urinary iodine concentration : effects of urine dilution and collection timing |
|---|
| Avtorji: | ID Oblak, Adrijana (Avtor)
ID Hribar, Maša (Avtor)
ID Hristov, Hristo (Avtor)
ID Gregorič, Matej (Avtor)
ID Blaznik, Urška (Avtor)
ID Osredkar, Joško (Avtor)
ID Kušar, Anita (Avtor)
ID Žmitek, Katja (Avtor)
ID Lavriša, Živa (Avtor)
ID Zaletel, Tjaša (Avtor)
ID Krhin, Blaž (Avtor)
ID Pravst, Igor (Avtor)
ID Gaberšček, Simona (Avtor)
ID Zaletel, Katja (Avtor) |
|---|
| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://www.nature.com/articles/s41430-024-01492-y
 PDF - Predstavitvena datoteka, prenos (439,07 KB)
MD5: CB1D38BF8DFE2140ACC95A129BB55F40
|
|---|
| Jezik: | Angleški jezik |
|---|
| Tipologija: | 1.01 - Izvirni znanstveni članek |
|---|
| Organizacija: |  NUTRIS - Inštitut za nutricionistiko
|
|---|
| Povzetek: | OBJECTIVES: In population studies, iodine intake estimation relies on median urinary iodine concentration (UIC). However, interpreting UIC measurements can be challenging. METHODS: In our study, we included 772 adult participants from three groups: nationally representative gender-mixed, women of reproductive age, and pregnant women. We measured UIC and urinary creatinine (U-Cr) to calculate the iodine-to- creatinine ratio (I/Cr). U-Cr cut-off value of 0.226 g/L was used for differentiation between diluted and undiluted urine samples. After excluding samples below this cut-off, new median UIC and I/Cr ratios were calculated. We additionally evaluated the influence of urine sample collection time on UIC. RESULTS: Median UICs were 91.8 μg/L for nationally representative group, 58.3 μg/L for women of reproductive age, and 74.9 μg/L for pregnant women, while I/Cr ratios were 91.7, 102.0, and 159.2 μg/g, respectively. After implementing U-Cr cut-off and excluding all data where U-Cr was below cut-off, new median values were 93.4, 76.3, and 95.4 μg/L for UICs, and 88.6, 88.8, and 128.7 μg/g for I/Cr ratios, respectively. In women of reproductive age, median UIC was significantly lower in urine samples collected after 9:30 and after 12:00 as compared to samples collected before 9.30 (53.4, 57.8, and 97.3 μg/L, respectively). CONCLUSIONS: UIC results should be interpreted with caution, considering urine dilution and sample collection timing. U-Cr measurement should be included in population-based iodine intake studies, with corrections applied especially for pregnant women and younger adults, for whom morning is best for single-spot samples. |
|---|
| Ključne besede: | urine dilution, urinary iodine concentration |
|---|
| Status publikacije: | Objavljeno |
|---|
| Verzija publikacije: | Objavljena publikacija |
|---|
| Datum objave: | 01.01.2024 |
|---|
| Leto izida: | 2024 |
|---|
| Št. strani: | str. 1105-1110 |
|---|
| Številčenje: | Vol. 78 |
|---|
| PID: | 20.500.12556/DiRROS-24022  |
|---|
| UDK: | 616.6 |
|---|
| ISSN pri članku: | 0954-3007 |
|---|
| DOI: | 10.1038/s41430-024-01492-y |
|---|
| COBISS.SI-ID: | 205173251 |
|---|
| Avtorske pravice: | © The Author(s) 2024 |
|---|
| Opomba: | Soavtorji: Maša Hribar, Hristo Hristov, Matej Gregorič, Urška Blaznik, Joško Osredkar, Anita Kušar, Katja Žmitek, Živa Lavriša, Tjaša Zaletel, Blaž Krhin, Igor Pravst, Simona Gaberšček, Katja Zaletel;
|
|---|
| Datum objave v DiRROS: | 07.11.2025 |
|---|
| Število ogledov: | 277 |
|---|
| Število prenosov: | 94 |
|---|
| Metapodatki: |    |
|---|
|
:
|
Kopiraj citat |
|---|
| | | | Objavi na: |  |
|---|
Postavite miškin kazalec na naslov za izpis povzetka. Klik na naslov izpiše
podrobnosti ali sproži prenos. |
