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Naslov:ELIXIR and toxicology : a community in development [version 2; peer review: 2 approved]
Avtorji:ID Martens, Marvin (Avtor)
ID Stierum, Rob (Avtor)
ID EL Schymanski (Avtor)
ID Evelo, Chris T (Avtor)
ID Županič, Anže (Avtor)
Datoteke:URL URL - Izvorni URL, za dostop obiščite https://doi.org/10.12688/f1000research.74502.2
 
.pdf PDF - Predstavitvena datoteka, prenos (959,11 KB)
MD5: 3822FA428BDAC63CA54FC77E3778046D
 
Jezik:Angleški jezik
Tipologija:1.02 - Pregledni znanstveni članek
Organizacija:Logo NIB - Nacionalni inštitut za biologijo
Povzetek:Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology, and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.
Ključne besede:toxicology, ELIXIR, interoperability, FAIR
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Datum objave:03.10.2023
Leto izida:2023
Št. strani:str. 1-15
Številčenje:Vol. 10, art. no. ǂ1129
PID:20.500.12556/DiRROS-20067 Novo okno
UDK:615.9
ISSN pri članku:2046-1402
DOI:10.12688/f1000research.74502.2 Novo okno
COBISS.SI-ID:168137731 Novo okno
Opomba:Soavtorji: Rob Stierum, Emma L. Schymanski, Chris T. Evelo, Reza Aalizadeh, Hristo Aladjov, Kasia Arturi, Karine Audouze, Pavel Babica, Karel Berka, Jos Bessems, Ludek Blaha, Evan E. Bolton, Montserrat Cases, Dimitrios Ε. Damalas, Kirtan Dave, Marco Dilger, Thomas Exner, Daan P. Geerke, Roland Grafström, Alasdair Gray, John M. Hancock, Henner Hollert, Nina Jeliazkova, Danyel Jennen , Fabien Jourdan, Pascal Kahlem, Jana Klanova, Jos Kleinjans, Todor Kondic, Boï Kone, Iseult Lynch, Uko Maran, Sergio Martinez Cuesta, Hervé Ménager, Steffen Neumann, Penny Nymark, Herbert Oberacher, Noelia Ramirez, Sylvie Remy, Philippe Rocca-Serra, Reza M. Salek, Brett Sallach, Susanna-Assunta Sansone, Ferran Sanz, Haralambos Sarimveis, Sirarat Sarntivijai, Tobias Schulze, Jaroslav Slobodnik, Ola Spjuth, Jonathan Tedds, Nikolaos Thomaidis, Ralf J.M. Weber, Gerard J.P. van Westen, Craig E. Wheelock, Antony J. Williams, Hilda Witters, Barbara Zdrazil, Anže Županič, Egon L. Willighagen; Nasl. z nasl. zaslona; Opis vira z dne 12. 10. 2023;
Datum objave v DiRROS:05.08.2024
Število ogledov:259
Število prenosov:181
Metapodatki:XML DC-XML DC-RDF
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Gradivo je del revije

Naslov:F1000Research
Skrajšan naslov:F1000Research
Založnik:F1000Research
ISSN:2046-1402
COBISS.SI-ID:31416537 Novo okno

Gradivo je financirano iz projekta

Financer:EC - European Commission
Številka projekta:731075
Naslov:OpenRiskNet: Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment
Akronim:OpenRiskNet

Financer:EC - European Commission
Številka projekta:681002
Naslov:An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century
Akronim:EU-ToxRisk

Financer:EC - European Commission
Številka projekta:814572
Naslov:Innovative Nanoinformatics models and tools: towards a Solid, verified and Integrated Approach to Predictive (eco)Toxicology (NanoSolveIT)
Akronim:NanoSolveIT

Financer:EC - European Commission
Številka projekta:825712
Naslov:An integrative strategy of testing systems for identification of EDs related to metabolic disorders
Akronim:OBERON

Financer:EC - European Commission
Številka projekta:733032
Naslov:European Human Biomonitoring Initiative
Akronim:HBM4EU

Financer:EC - European Commission
Številka projekta:953183
Naslov:Advanced High Aspect Ratio and Multicomponent materials: towards comprehensive intelLigent tEsting and Safe by design Strategies
Akronim:HARMLESS

Financer:EC - European Commission
Številka projekta:814401
Naslov:Implementation of Risk Governance: meeting the needs of nanotechnology
Akronim:Gov4Nano

Financer:EC - European Commission
Številka projekta:896141
Naslov:The innovative wastewater-based epidemiology approach with the advances of high resolution mass spectrometry as a complementary biomonitoring tool for assessing the health status of a population
Akronim:NTS-EXPOSURE

Financer:EC - European Commission
Številka projekta:814425
Naslov:Risk Governance of Nanotechnology
Akronim:RiskGONE

Financer:EC - European Commission
Številka projekta:731032
Naslov:The European Nanotechnology Community Informatics Platform: Bridging data and disciplinary gaps for industry and regulators (NanoCommons)
Akronim:NanoCommons

Financer:EC - European Commission
Številka projekta:825489
Naslov:Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds
Akronim:GOLIATH

Financer:EC - European Commission
Številka projekta:814426
Naslov:Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.
Akronim:NanoInformaTIX

Financer:EC - European Commission
Številka projekta:859891
Naslov:Best chemical risk assessment professionals for maximum Ecosystem Services benefit
Akronim:PRORISK

Financer:EC - European Commission
Številka projekta:965406
Naslov:Toward Precision Toxicology: New Approach Methodologies for Chemical Safety
Akronim:PrecisionTox

Financer:WT - Wellcome Trust
Številka projekta:212930
Naslov:The FAIRsharing service: supporting the research life-cycle

Financer:Drugi - Drug financer ali več financerjev
Številka projekta:N2020-0005
Naslov:Swedish Fund for Research Without Animal Experiments

Financer:EC - European Commission
Program financ.:the European Union,'s LIFE program
Številka projekta:LIFE17 ENV/SK/000355
Akronim:LIFE-APEX

Financer:Drugi - Drug financer ali več financerjev
Številka projekta:3718 674150
Akronim:PHION

Financer:Drugi - Drug financer ali več financerjev
Številka projekta:H2020-EU 965406
Naslov:H2020 Precision Toxicology project

Financer:Drugi - Drug financer ali več financerjev
Številka projekta:208381/A/17/Z
Naslov:the Wellcome ISA-InterMine project

Financer:Drugi - Drug financer ali več financerjev
Številka projekta:212930/Z/18/Z
Naslov:the Wellcome FAIRsharing project

Financer:Drugi - Drug financer ali več financerjev
Številka projekta:CEFIC-LRI EEM9.3-IC/EEM9.4
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Financer:ANR - French National Research Agency
Številka projekta:ANRINBS-0010
Naslov:the national metabolomics and fluxomics infrastructure
Akronim:MetaboHUB

Financer:Drugi - Drug financer ali več financerjev
Številka projekta:441958208
Akronim:NFDI4Chem

Financer:Drugi - Drug financer ali več financerjev
Program financ.:BMBF
Številka projekta:031L0107

Financer:Drugi - Drug financer ali več financerjev
Program financ.:Luxembourg National Research Fund
Številka projekta:A18/BM/12341006

Financer:Drugi - Drug financer ali več financerjev
Program financ.:Instituto de Salud Carlos III
Številka projekta:CO19/00060
Naslov:Miguel Servet contract

Financer:Drugi - Drug financer ali več financerjev
Program financ.:Ministry of Education and Research, Republic of Estonia
Številka projekta:PRG1509

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Program financ.:Foundation Archimedes
Številka projekta:TK143
Naslov:Centre of Excellence in Molecular Cell Engineering

Financer:NIH - National Institutes of Health
Program financ.:e National Center for Biotechnology Information of the National Library of Medicine

Licence

Licenca:CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.

Sekundarni jezik

Jezik:Slovenski jezik
Ključne besede:toksikologija, interoperabilnost, podatkovne zbirke


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