| Naslov: | Dietary iodine intake, therapy with radioiodine, and anaplastic thyroid carcinoma |
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| Avtorji: | ID Bešić, Nikola (Avtor)
ID Gazić, Barbara (Avtor) |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://content.sciendo.com/view/journals/raon/54/2/article-p187.xml
 PDF - Predstavitvena datoteka, prenos (324,36 KB)
MD5: C79A1EE56C4AA1DDD3CD13F690B8E07C
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  OI - Onkološki inštitut Ljubljana
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| Povzetek: | Anaplastic thyroid cancer (ATC) is one of the most aggressive tumors. The aim of the study was to determine the correlation between a higher dietary intake of iodine, frequency of ATC and the characteristics of ATC, and to find out how often patients with ATC had a history of radioiodine (RAI) therapy. Patients and methods. This retrospective study included 220 patients (152 females, 68 males; mean age 68 years) with ATC who were treated in our country from 1972 to 2017. The salt was iodinated with 10 mg of potassium iodide/ kg before 1999, and with 25 mg of potassium iodide/kg thereafter. The patients were assorted into 15-year periods: 1972%1986, 1987%2001, and 2002%2017. Results. The incidence of ATC decreased after a higher iodination of salt (p = 0.04). Patients are nowadays older (p = 0.013) and have less frequent lymph node metastases (p = 0.012). The frequency of distant metastases did not change over time. The median survival of patients in the first, second, and third periods was 3, 4, and 3 months, respectively (p < 0.05). The history of RAI therapy was present in 7.7% of patients. Conclusions. The number of patients with a history of RAI therapy did not change statistically over time. The incidence of ATC in Slovenia decreased probably because of higher salt iodination. |
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| Ključne besede: | anaplastic thyroid carcinoma, iodination of salt, treatment, survival |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Datum objave: | 01.06.2020 |
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| Založnik: | Association of Radiology and Oncology |
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| Leto izida: | 2020 |
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| Št. strani: | str. 187-193, VI |
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| Številčenje: | Vol. 54, no. 2 |
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| Izvor: | Ljubljana |
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| PID: | 20.500.12556/DiRROS-19285  |
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| UDK: | 616.4 |
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| ISSN pri članku: | 1318-2099 |
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| DOI: | 10.2478/raon-2020-0023 |
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| COBISS.SI-ID: | 14368003 |
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| Avtorske pravice: | by Authors |
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| Datum objave v DiRROS: | 12.07.2024 |
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| Število ogledov: | 923 |
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| Število prenosov: | 518 |
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| Metapodatki: |    |
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