| Naslov: | Stress knowledge map : a knowledge graph resource for systems biology analysis of plant stress responses |
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| Avtorji: | ID Bleker, Carissa (Avtor)
ID Ramšak, Živa (Avtor)
ID Bittner, Andras (Avtor)
ID Podpečan, Vid (Avtor)
ID Zagorščak, Maja (Avtor)
ID Wurzinger, Bernhard (Avtor)
ID Baebler, Špela (Avtor)
ID Petek, Marko (Avtor)
ID Križnik, Maja (Avtor)
ID Županič, Anže (Avtor)
ID Gruden, Kristina (Avtor) |
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| Datoteke: |  URL - Izvorni URL, za dostop obiščite https://doi.org/10.1016/j.xplc.2024.100920
URL - Izvorni URL, za dostop obiščite https://skm.nib.si
 PDF - Predstavitvena datoteka, prenos (1,35 MB)
MD5: E411194F1EC267F27BE12CD3DB83A435
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  NIB - Nacionalni inštitut za biologijo
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| Povzetek: | Stress Knowledge Map (SKM; https://skm.nib.si) is a publicly available resource containing two complementary knowledge graphs that describe the current knowledge of biochemical, signaling, and regulatory molecular interactions in plants: a highly curated model of plant stress signaling (PSS; 543 reactions) and a large comprehensive knowledge network (488 390 interactions). Both were constructed by domain experts through systematic curation of diverse literature and database resources. SKM provides a single entry point for investigations of plant stress response and related growth trade-offs, as well as interactive explorations of current knowledge. PSS is also formulated as a qualitative and quantitative model for systems biology and thus represents a starting point for a plant digital twin. Here, we describe the features of SKM and show, through two case studies, how it can be used for complex analyses, including systematic hypothesis generation and design of validation experiments, or to gain new insights into experimental observations in plant biology. |
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| Ključne besede: | Stress knowledge map, knowledge graph, knowledge network, entry point, plant digital twin, plant stress responses, plant signaling, systems biology |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Datum objave: | 10.06.2024 |
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| Leto izida: | 2024 |
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| Št. strani: | str. 1-15 |
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| Številčenje: | iss. 6, [art. no.] ǂ100920 |
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| PID: | 20.500.12556/DiRROS-19098  |
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| UDK: | 577.2 |
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| ISSN pri članku: | 2590-3462 |
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| DOI: | 10.1016/j.xplc.2024.100920 |
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| COBISS.SI-ID: | 198383363 |
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| Opomba: | Soavtorji: Živa Ramšak, Andras Bittner, Vid Podpečan, Maja Zagorščak, Bernhard Wurzinger, Špela Baebler, Marko Petek, Maja Križnik, Annelotte van Dieren, Juliane Gruber, Leila Afjehi-Sadat, Wolfram Weckwerth, Anže Županič, Markus Teige, Ute C. Vothknecht and Kristina Gruden;
Nasl. z nasl. zaslona;
Opis vira z dne 11. 6. 2024;
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| Datum objave v DiRROS: | 11.06.2024 |
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| Število ogledov: | 530 |
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| Število prenosov: | 247 |
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| Metapodatki: |    |
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