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Naslov:Pulmonary pathology and COVID-19 : lessons from autopsy : the experience of European pulmonary pathologists
Avtorji:ID Calabrese, Fiorella (Avtor)
ID Pezzuto, Federica (Avtor)
ID Fortarezza, Francesco (Avtor)
ID Hofman, Paul (Avtor)
ID Kern, Izidor, Klinika Golnik (Avtor)
ID Panizo, Angel (Avtor)
ID Thüsen, Jan von der (Avtor)
ID Timofeev, Sergei (Avtor)
ID Gorkiewicz, Gregor (Avtor)
ID Lunardi, Francesca (Avtor)
Datoteke:.pdf PDF - Predstavitvena datoteka, prenos (1,55 MB)
MD5: 256373B8D6A083C6B61D8B373489EFD4
 
URL URL - Izvorni URL, za dostop obiščite https://link.springer.com/content/pdf/10.1007/s00428-020-02886-6.pdf
 
Jezik:Angleški jezik
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:Logo UKPBAG - Univerzitetna klinika za pljučne bolezni in alergijo Golnik
Povzetek:Since its initial recognition in December 2019, Coronavirus disease 19 (COVID-19) has quickly spread to a pandemic infectious disease. The causative agent has been recognized as a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), primarily affecting the respiratory tract. To date, no vaccines are available nor any specific treatment. To limit the number of infections, strict directives have been issued by governments that have been translated into equally rigorous guidelines notably for post-mortem examinations by international and national scientific societies. The recommendations for biosafety control required during specimen collection and handling have strongly limited the practice of autopsies of the COVID-19 patients to a few adequate laboratories. A full pathological examination has always been considered an important tool to better understand the pathophysiology of diseases, especially when the knowledge of an emerging disorder is limited and the impact on the healthcare system is significant. The first evidence of diffuse alveolar damage in the context of an acute respiratory distress syndrome has now been joined by the latest findings that report a more complex scenario in COVID-19, including a vascular involvement and a wide spectrum of associated pathologies. Ancillary tools such as electron microscopy and molecular biology used on autoptic tissue samples from autopsy are also significantly contributing to confirm and/or identify new aspects useful for a deeper knowledge of the pathogenetic mechanisms. This article will review and summarize the pathological findings described in COVID-19 until now, chiefly focusing on the respiratory tract, highlighting the importance of autopsy towards a better knowledge of this disease.
Ključne besede:COVID-19, SARS-CoV-2, autopsy, lung, pandemic
Status publikacije:V tisku
Verzija publikacije:Recenzirani rokopis
Kraj izida:Nemčija
Založnik:Springer Nature
Leto izida:2020
Št. strani:str. [1-14]
Številčenje:Vol. 477, iss.
PID:20.500.12556/DiRROS-12301 Novo okno
UDK:616.2
ISSN pri članku:1432-2307
DOI:10.1007/s00428-020-02886-6 Novo okno
COBISS.SI-ID:23930627 Novo okno
Avtorske pravice:The Author(s) 2020
Opomba:Nasl. z nasl. zaslona; Soavtor iz Slovenije: Izidor Kern; Opis vira z dne 29. 7. 2020;
Datum objave v DiRROS:31.07.2020
Število ogledov:14590
Število prenosov:1424
Metapodatki:XML DC-XML DC-RDF
:
CALABRESE, Fiorella, PEZZUTO, Federica, FORTAREZZA, Francesco, HOFMAN, Paul, KERN, Izidor, PANIZO, Angel, THÜSEN, Jan von der, TIMOFEEV, Sergei, GORKIEWICZ, Gregor in LUNARDI, Francesca, 2020, Pulmonary pathology and COVID-19 : lessons from autopsy : the experience of European pulmonary pathologists. Virchows archiv [na spletu]. 2020. Vol. 477, p. 1–14. [Dostopano 17 marec 2025]. DOI 10.1007/s00428-020-02886-6. Pridobljeno s: https://dirros.openscience.si/IzpisGradiva.php?lang=slv&id=12301
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Gradivo je del revije

Naslov:Virchows archiv
Založnik:Springer
ISSN:1432-2307
COBISS.SI-ID:2517524 Novo okno

Licence

Licenca:CC BY-NC 4.0, Creative Commons Priznanje avtorstva-Nekomercialno 4.0 Mednarodna
Povezava:http://creativecommons.org/licenses/by-nc/4.0/deed.sl
Opis:Licenca Creative Commons, ki prepoveduje komercialno uporabo, vendar uporabniki ne rabijo upravljati materialnih avtorskih pravic na izpeljanih delih z enako licenco.
Začetek licenciranja:28.06.2020

Sekundarni jezik

Jezik:Ni določen
Ključne besede:covid-19, SARS-CoV-2, obdukcija, pljuča, pandemija


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