21. Documenting metrological traceability as intended by ISO 15189:2012 : a consensus statement about the practice of the implementation and auditing of this norm elementMarc H. M. Thelen, Florent Vanstapel, Pika Meško-Brguljan, Bernard Gouget, Guilaine Boursier, Edward Barrett, Christos Kroupis, Maria Lohmander, Luděk Šprongl, Tatjana Vodnik, 2019, izvirni znanstveni članek Povzetek: ISO15189:2012 requires medical laboratories to document metrological traceability of their results. While the ISO17511:2003 standard on metrological traceability in laboratory medicine requires the use of the highest available level in the traceability chain, it recognizes that for many measurands there is no reference above the manufacturer's selected measurement procedure and the manufacturer's working calibrator. Some immunoassays, although they intend to measure the same quantity and may even refer to the same reference material, unfortunately produce different results because of differences in analytical selectivity as manufacturers select different epitopes and antibodies for the same analyte. In other cases, the cause is the use of reference materials, which are not commutable. The uncertainty associated with the result is another important aspect in metrological traceability implementation. As the measurement uncertainty on the clinical samples is influenced by the uncertainty of all steps higher in the traceability chain, laboratories should be provided with adequate and appropriate information on the uncertainty of the value assignment to the commercial calibrators that they use. Although the between-lot variation in value assignment will manifest itself as part of the long-term imprecision as estimated by the end-user, information on worst-case to be expected lot-lot variation has to be communicated to the end-user by the IVD provider. When laboratories use ancillary equipment that potentially could have a critical contribution to the reported results, such equipment needs verification of its proper calibration and criticality to the result uncertainty could be assessed by an approach based on risk analysis, which is a key element of ISO15189:2012 anyway. This paper discusses how the requirement for metrological traceability as stated in ISO15189 should be met by the medical laboratory and how this should be assessed by accreditation bodies. Ključne besede: laboratories, medical laboratory science, risk management, quality control, quality improvement, health care quality assurance, metrological traceability Objavljeno v DiRROS: 22.10.2020; Ogledov: 1264; Prenosov: 279 Povezava na datoteko |
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23. Factors influencing growth of mature sycamore trees (Acer pseudoplatanus L.) on carbonate bedrockAleš Kadunc, Marijan Kotar, 2005, izvirni znanstveni članek Povzetek: This paper presents the growth potential of sycamore (Acer pseudoplatanus L.) on four types of forest sites located on carbonate bedrock. The research covers sycamore sites (Aceri-Fraxinetum ill.), beech sites (Lamio orvalae-Fagetum), beech sites planted with Norway spruce, and silver fir-beechsites (Omphalodo-Fagetum aceretosum). The analyses for each forest type were carried out on five plots. Our aim was to determine the effect of site factors and stand parameters on sycamore growth. Site productivity (SP) is positively correlated with soil depth, coarse silt percentage in the cambichorizon, the content of phosphorus in leaves and, partly, with potassium. The effect of nitrogen supply on height growth or SP was not confirmed. Furthermore, height growth on sites with a higher rate of nutrient cycling, higher macronutrient supply and higher sand percentage in the cambic horizon is significantly faster. As to the growth of basal area, in addition to positive dependences of crown size, many other correlations with site factors were confirmed. Ključne besede: beech stand, growing stock, stand value, current volume increment, current value increment, quality structure, social collective Objavljeno v DiRROS: 12.07.2017; Ogledov: 4445; Prenosov: 1821 Celotno besedilo (185,52 KB) |
24. Amino- and ionic liquid-functionalised nanocrystalline ZnO via silane anchoring - an antimicrobial synergyMarjeta Čepin, Vasko Jovanovski, Matejka Podlogar, Zorica Crnjak Orel, 2015, izvirni znanstveni članek Povzetek: Temperature has critical impact on food quality and
safety within food supply chain, therefore, food should
be kept at the defined storage temperature range.
Final consumer should be assured when buying food
about actual temperature and thermal history of the
selected food product and this is why it should be indicated
on the packed or prepacked item.
The chromogenic temperature indicator for cold food
chain was prepared from suitable active material
packed in the properly structured holder. When temperature
rises above the defined storage temperature,
the active material changes colour and physical state
(solid/liquid). Simultaneously, special packaging structure
enables irreversible recording of the time exposed
to the elevated temperature. The active material was
made of thermochromic composite, consisting of dye,
developer and solvent. It changes colour at its melting
point, being coloured below and discoloured above
it. The temperature is called activation temperature of
the composite. Its value was adjusted by appropriate
solvent and additives used for preparation of the composite,
to reach the desired value. The temperature
dependent colour change of the composite was determined
by colorimetric measurements. The conditions
for best observation of the change by naked eye were
also examined. The structure of the active material’s
holder was analyzed for best displaying of the time
spend at high temperature (above the activation temperature).
Functioning of the indicator was examined with
growth of pathogens as a function of migration of
the active material at temperature above the required
storage temperature of the food. It was found out that
the described chromogenic temperature indicator for
cold food chain shows the thermal history of food storage
by colour-, phase- and migration changes of the
active composite material and consequently would be
reliable as indicator in cold food chain to indicate temperature
abuse and would disclose potential growth of
psychrophilic microorganisms. Ključne besede: Chromogenic temperature indicator, Food
cold chain, Food quality and safety, Temperature control, Thermal history Objavljeno v DiRROS: 16.12.2014; Ogledov: 6177; Prenosov: 946 Povezava na celotno besedilo |