Iskanje po repozitoriju

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Povzetek: Seeking to move beyond a focus on former colonial Metropoles and Cold War superpowers, and zooming in on peripheral modernization projects, this conference investigates the ‘in-between’ instances of economic cooperation in the self-professed developing countries in Africa, Asia, and South America. The conference primarily focuses on those dynamic players in the postcolonial world which circumvented the habitual East-West and North-South cleavages and presented themselves as: 1) neutral (e.g. Austria, Sweden, Ireland), 2) non-aligned (e.g. Yugoslavia, India, Egypt), 3) pursuing more independent socialist course (e.g. Romania, Cuba, China), 4) allegedly not sharing the colonial past with other Western European nations (e.g. West Germany, Italy), or 5) successfully ‘catching up’ with the most developed nations (e.g. Japan, Israel, South Korea). While not excluding examples of Cold War superpowers and former colonial metropoles’ inserting themselves into this newly emerging multidirectional development consensus the conference focuses on the above described, liminal examples of bilateral collaboration, particularly contributions emphasizing tri- and multilateral efforts between ‘East’, ‘South’ and ‘West’.
Objavljeno v DiRROS: 16.09.2024; Ogledov: 55; Prenosov: 40
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Povzetek: The cholinergic system has been implicated in postural deficits, in particular falls, in Parkinson’s disease. Falls and freezing of gait typically occur during dynamic and challenging balance and gait conditions, such as when initiating gait, experiencing postural perturbations, or making turns. However, the precise cholinergic neural substrate underlying dynamic postural and gait changes remains poorly understood. The aim of this study was to investigate whether brain vesicular acetylcholine transporter binding, as measured with [18F]-fluoroethoxybenzovesamicolbinding PET, correlates with dynamic gait and balance impairments in 125 patients with Parkinson’s disease (mean age 66.89±7.71 years) using the abbreviated Balance Evaluation Systems Test total and its four functional domain sub-scores (anticipatory postural control, reactive postural control, dynamic gait, and sensory integration). Whole brain false discoverycorrected (P < 0.05) correlations for total abbreviated Balance Evaluation Systems Test scores included the following bilateral or asymmetric hemispheric regions: gyrus rectus, orbitofrontal cortex, anterior part of the dorsomedial prefrontal cortex, dorsolateral prefrontal cortex, cingulum, frontotemporal opercula, insula, fimbria, right temporal pole, mesiotemporal, parietal and visual cortices, caudate nucleus, lateral and medial geniculate bodies, thalamus, lingual gyrus, cerebellar hemisphere lobule VI, left cerebellar crus I, superior cerebellar peduncles, flocculus, and nodulus. No significant correlations were found for the putamen or anteroventral putamen. The four domain-specific sub-scores demonstrated overlapping cholinergic topography in the metathalamus, fimbria, thalamus proper, and prefrontal cortices but also showed distinct topographic variations. For example, reactive postural control functions involved the right flocculus but not the upper brainstem regions. The anterior cingulum associated with reactive postural control whereas the posterior cingulum correlated with anticipatory control. The spatial extent of associated cholinergic system changes were least for dynamic gait and sensory orientation functional domains compared to the anticipatory and reactive postural control functions. We conclude that specific aspects of dynamic balance and gait deficits in Parkinson’s disease associate with overlapping but also distinct patterns of cerebral cholinergic system changes in numerous brain regions. Our study also presents novel evidence of cholinergic topography involved in dynamic balance and gait in Parkinson’s disease that have not been typically associated with mobility disturbances, such as the right anterior temporal pole, right anterior part of the dorsomedial prefrontal cortex, gyrus rectus, fimbria, lingual gyrus, flocculus, nodulus and right cerebellar hemisphere lobules VI and left crus I.
Ključne besede: Parkinson’s disease, dynamic balance, cholinergic, PET
Objavljeno v DiRROS: 30.08.2024; Ogledov: 120; Prenosov: 434
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Povzetek: This Toolkit was created by the Law Institute of the Science and Research Centre of Koper, Slovenia, as a deliverable of the Innocent project funded by the European Commission under the JUST Programme and coordinated by the Law and Internet Foundation, Bulgaria. It aims at enhancing the application of the presumption of innocence when handling electronic evidence (e-evidence) in criminal proceedings and empowering legal practitioners to critically review e-evidence from procedural rights perspective. It is designed to enhance understanding of the legal and practical challenges encountered by judges, prosecutors and defence lawyers (particularly those operating in Central and Eastern Europe) in the acquisition of e-evidence by law enforcement agencies, evaluation of admissibility of e-evidence by judges, and cross-border access to and exchange of e-evidence. Exploring the different stages in the ‘life cycle’ of e-evidence, this Toolkit concerns data and evidence stored in various electronic devices and online information systems, including computers, smartphones, tablets, smartwatches, electronic appliances, portable media (e.g., USB sticks, external hard drives) and clouds, associated with individuals suspected or accused of criminal offenses, as well as those in the possession of other individuals. It also concerns electronic data and evidence held by telecommunication and internet service providers registered in domestic or foreign jurisdictions. However, it does not address legal and/or practical considerations related to interception and obtaining real-time electronic data and evidence from telecommunications operators and refrains from exploring issues concerning the collection of electronic data (and evidence) through techniques of mass surveillance, as well as strategies like “predictive risk-assessment” or other similar approaches aimed at preventing crime and enhancing law enforcement capabilities.
Objavljeno v DiRROS: 09.08.2024; Ogledov: 206; Prenosov: 153
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Povzetek: Background: The accelerated aging of the world’s population will lead to an increase in the number of older people in the workforce. Computerized Cognitive Training (CCT) is effective in improving cognitive outcomes, but its benefits for older workers remain controversial. We investigate the real-world efficacy of CCT in the workplace, focusing on employees aged 50+ years from a public sector agency. Methods: Case managers (n = 82) were randomized to either an intervention group (24 40 min CCT sessions two times per week) or a waiting list passive control group. Cognitive ability, well-being, job satisfaction, and productivity outcome measures were collected and assessed before and after CCT or the comparable control wait time. Results: Participants undergoing CCT improved on a task of executive functioning (p = 0.04). There was a trend toward a change in work productivity after CCT (p = 0.09), with the control group showing a significant decrease (p = 0.02), while the intervention group remained stable. Conclusions: CCT during office hours has a positive effect on cognition and well-being without affecting productivity among white-collar office workers. CCT could be considered as an intervention to support the older workforce in managing the cognitive and behavioral challenges of changing workplace demands.
Ključne besede: older employees, 50+, computerized cognitive training (CCT), productivity, well-being
Objavljeno v DiRROS: 05.08.2024; Ogledov: 193; Prenosov: 265
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Povzetek: The adaptation of autochthonous olive varieties to local soil and climatic conditions can lead to a unique chemical composition and characteristics of olive oils that may differ from the generally accepted quality standards set out in the International Olive Oil Council strategy documents and EU regulations. Therefore, the fatty acid composition, biophenol, tocopherol, sterol and triterpenic dialcohol content and composition of the autochthonous Slovenian olive varieties ‘Buga’, ‘Crnica’ ˇ and ‘Drobnica’ were studied for a three-year period with the aim of valorising the characteristics of the three olive varieties. Standardised and accredited analytical methods in accordance with SIST EN ISO/IEC 17025:2017 were applied. The results of the investigation showed that the highest average amount of oleic acid (75.75%) was found in the oils of the ‘Crnica’ variety, followed by the ‘Drobnica’ ˇ (72.06%) and the ‘Buga’ (68.73%). All three varieties are a good source of total biophenols (‘Buga’ 616 mg/kg, ‘Drobnica’ 569 mg/kg and ‘Crnica’ 427 mg/kg) and ˇ α-tocopherol (‘Buga’ 378 mg/kg, ‘Drobnica’ 279 mg/kg, and ‘Crnica’ 243 mg/kg). ‘Buga’ and ‘Drobnica’ are characterised by high ˇ amounts of total sterols, 2468 mg/kg and 2391 mg/kg, respectively, while ‘Crnica’ oils, in comparison, ˇ showed a lower average value of total sterols (1351 mg/kg). Due to their exceptional chemical composition, ‘Buga’, ‘Crnica’ and ‘Drobnica’ show great potential for the further cultivation and ˇ valorisation of traditional olive oil production in the region, thus contributing to the preservation of biodiversity and local traditions. The quality parameters of olive oil from the autochthonous Slovenian olive varieties ‘Buga’, ‘Crnica’ and ‘Drobnica’ also fulfil the limits for extra virgin olive oil ˇ according to the Commission Delegated Regulation (EU) 2022/2104, despite local climatic influences. However, accelerated growth due to climatic changes affecting early harvest can lead to them falling outside these limits, which was observed in particular for the ‘Buga’ variety in terms of the linoleic acid content. This study emphasises the importance of timing the harvest to achieve optimum maturity and meet EU quality standards, taking into account the genetic makeup of the varieties and their response to the current climatic conditions.
Ključne besede: olive, autochthonous Slovenian olive varieties, olive oil, bioactive compounds, chemistry, characterisation
Objavljeno v DiRROS: 24.07.2024; Ogledov: 178; Prenosov: 92
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