41. Tree rings, wood density and climate–growth relationships of four Douglas-fir provenances in sub-Mediterranean SloveniaLuka Krajnc, Jožica Gričar, Jernej Jevšenak, Polona Hafner, Robert Brus, 2022, izvirni znanstveni članek Povzetek: Tree rings, wood density and the climate–growth relationship of four Douglas-fir provenances were analysed separately for the juvenile and adult phases. Four provenances were selected from an existing IUFRO provenance trial planted in 1971 based on their diameter at breast height and vitality. Increment cores were extracted from individual trees, on which we measured tree-ring widths (RW), earlywood widths (EWW) and latewood widths (LWW). Wood density was assessed in standing trees using resistance drilling. The climate–growth correlations were calculated between provenance chronologies of RW, EWW, LWW and latewood share, and the day-wise aggregated Standardised Precipitation-Evapotranspiration Index (SPEI). The analysis was done separately for the juvenile and mature phases of growth. Provenances 1064 (Jefferson) and 1080 (Yelm) exhibited larger annual radial increments than provenances 1028 (Merrit) and 1089 (Cathlamet). The two provenances with the highest annual radial increment in the juvenile phase did not exhibit the same trend in the adult phase. In all provenances, RW, and consequently EWW and LWW, were wider in the juvenile than in adult phase. The share of latewood was in all cases higher in juvenile wood than in mature wood. All four provenances had similar wood densities in both analyzed growth phases. Our analysis showed that when selecting the most promising provenance for planting, possible changes in relative growth rate from the juvenile to adult phase need to be considered.
Ključne besede: Pseudotsuga menziesii, SPEI, juvenile phase, adult phase, latewood share, resistance drilling
Objavljeno v DiRROS: 21.11.2022; Ogledov: 481; Prenosov: 160
 Celotno besedilo (3,07 MB)
Gradivo ima več datotek! Več... |
42. |
43. Review of the research and evolution of landslides in the hinterland of Koroška Bela settlement (NW Slovenia)Tina Peternel, Ela Šegina, Jernej Jež, Mateja Jemec Auflič, Mitja Janža, Janko Logar, Matjaž Mikoš, Miloš Bavec, 2022, izvirni znanstveni članek Povzetek: This paper gives an overview of landslide research and the activity of landslides located above the Koroška Bela settlement in Northwest Slovenia. There are several landslides in this area and they pose a direct threat to the settlement below. The settlement is very densely populated (about 2,100 inhabitants) and has well-developed industry and infrastructure. It is built on deposits from past debris flows, indicating that large slope mass movements have occurred in the past. In this regard, the hinterland of Koroška Bela has been investigated since 2006, within the framework of various research, technical and European projects. The most extensive geological and geotechnical investigations were carried out after April 2017, when part of the Čikla landslide collapsed and mobilised into a debris flow. All of the investigations which have been carried out over the years revealed that the hinterland of Koroška Bela is characterised by high landslide activity due to geological, hydrogeological and tectonic conditions. In order to protect people and their property, it is essential to implement a holistic mitigation measure which includes remediation works (drainage works, debris flow breaker, etc.) and non-structural measures (monitoring system, early warning system, risk management, etc.). Regular and continuous monitoring of all landslides is also crucial to observe the landslide dynamics and evaluate the effectiveness of structural mitigation measures.
Ključne besede: landslide, debris flow, research, monitoring, landslide evolution, Koroška Bela
Objavljeno v DiRROS: 03.10.2022; Ogledov: 666; Prenosov: 186
Celotno besedilo (11,09 MB) |
44. Long-term survival of a patient with liver metastases from clear cell gastric adenocarcinoma after multimodality treatment including interventional oncology techniques : case reportVesna Jugovec, Jernej Benedik, Jera Jeruc, Peter Popović, 2022, kratki znanstveni prispevek Povzetek: Background: Gastric cancer (GC) is the fourth most common cancer and the third leading cancer-related cause of death worldwide since most patients are diagnosed at an advanced stage. The majority of GCs are adenocarcinomas (ACs), and the poorly characterized clear cell AC represents a unique subgroup of GCs and is an independent marker of poor prognosis. Even though the prognosis for patients with advanced GC is poor we present a report of a patient with long-term survival despite having liver metastases from clear cell gastric AC. Case presentation: A 45-year-old male with clear cell gastric AC underwent subtotal gastrectomy and postoperative chemoradiation. Only a year and a half after his initial treatment the disease spread to his liver. He received two lines of chemotherapy treatment within the next two years before a right hepatectomy was suggested. Due to an initially insufficient future liver remnant (FLR), transarterial chemoembolization (TACE) and portal vein embolization (PVE) were performed, which made the surgical procedure possible. Shortly after a disease progression in the remaining liver was detected. In the following three years the patient was treated with a carefully planned combination of systemic therapy and different interventional oncology techniques including selective internal radiation therapy (SIRT) and TACE. And as illustrated, an attentive, patient-tailored, multimodality treatment approach can sometimes greatly benefit our patients as he had an overall survival of 88 months despite the poor prognosis of his disease. Conclusion: To the best of our knowledge, this report is the first to describe a patient with liver metastases from clear cell gastric AC treated with interventional oncology techniques (PVE, TACE, and SIRT) in combination with other locoregional and systemic therapies thereby presenting that these interventional oncology techniques can be successfully integrated into long-term management of non-conventional liver tumors.
Ključne besede: gastric adenocarcinoma, survival, multimodality treatment
Objavljeno v DiRROS: 15.09.2022; Ogledov: 417; Prenosov: 251
Celotno besedilo (1,76 MB)
Gradivo ima več datotek! Več... |
45. Different wood anatomical and growth responses in European beech (Fagus sylvatica L.) at three forest sites in SloveniaDomen Arnič, Jožica Gričar, Jernej Jevšenak, Gregor Božič, Georg von Arx, Peter Prislan, 2021, izvirni znanstveni članek Povzetek: European beech (Fagus sylvatica L.) adapts to local growing conditions to enhance its performance. In response to variations in climatic conditions, beech trees adjust leaf phenology, cambial phenology, and wood formation patterns, which result in different treering widths (TRWs) and wood anatomy. Chronologies of tree ring width and vessel features [i.e., mean vessel area (MVA), vessel density (VD), and relative conductive area (RCTA)] were produced for the 1960%2016 period for three sites that differ in climatic regimes and spring leaf phenology (two early- and one late-flushing populations). These data were used to investigate long-term relationships between climatic conditions and anatomical features of four quarters of tree-rings at annual and intra-annual scales. In addition, we investigated how TRW and vessel features adjust in response to extreme weather events (i.e., summer drought). We found significant differences in TRW, VD, and RCTA among the selected sites. Precipitation and maximum temperature before and during the growing season were the most important climatic factors affecting TRW and vessel characteristics. We confirmed differences in climate-growth relationships between the selected sites, late flushing beech population at Idrija showing the least pronounced response to climate. MVA was the only vessel trait that showed no relationship with TRW or other vessel features. The relationship between MVA and climatic factors evaluated at intra-annual scale indicated that vessel area in the first quarter of tree-ring were mainly influenced by climatic conditions in the previous growing season, while vessel area in the second to fourth quarters of tree ring width was mainly influenced by maximum temperature and precipitation in the current growing season. When comparing wet and dry years, beech from all sites showed a similar response, with reduced TRW and changes in intra-annual variation in vessel area. Our findings suggest that changes in temperature and precipitation regimes as predicted by most climate change scenarios will affect tree-ring increments and wood structure in beech, yet the response between sites or populations may differ.
Ključne besede: Fagus sylvatica, wood anatomy, tracheograms, dendrochronology, intra specific plasticity
Objavljeno v DiRROS: 22.07.2022; Ogledov: 536; Prenosov: 371
Celotno besedilo (15,28 MB)
Gradivo ima več datotek! Več... |
46. Modelling seasonal dynamics of secondary growth in RJernej Jevšenak, Jožica Gričar, Sergio Rossi, Peter Prislan, 2022, izvirni znanstveni članek Povzetek: The monitoring of seasonal radial growth of woody plants addresses the ultimate question of when, how and why trees grow. Assessing the growth dynamics is important to quantify the effect of environmental drivers and understand how woody species will deal with the ongoing climatic changes. One of the crucial steps in the analyses of seasonal radial growth is to model the dynamics of xylem and phloem formation based on increment measurements on samples taken at relatively short intervals during the growing season. The most common approach is the use of the Gompertz equation, while other approaches, such as general additive models (GAMs) and generalised linear models (GLMs), have also been tested in recent years. For the first time, we explored artificial neural networks with Bayesian regularisation algorithm (BRNNs) and show that this method is easy to use, resistant to overfitting, tends to yield s-shaped curves and is therefore suitable for deriving temporal dynamics of secondary tree growth. We propose two data processing algorithms that allow more flexible fits. The main result of our work is the XPSgrowth() function implemented in the radial Tree Growth (rTG) R package, that can be used to evaluate and compare three modelling approaches: BRNN, GAM and the Gompertz function. The newly developed function, tested on intra-seasonal xylem and phloem formation data, has potential applications in many ecological and environmental disciplines where growth is expressed as a function of time. Different approaches were evaluated in terms of prediction error, while fitted curves were visually compared to derive their main characteristics. Our results suggest that there is no single best fitting method, therefore we recommend testing different fitting methods and selection of the optimal one.
Ključne besede: artificial neural networks, cambium, generalized additive model, Gompertz function, growing season, intra-annual time series
Objavljeno v DiRROS: 21.07.2022; Ogledov: 493; Prenosov: 331
Celotno besedilo (1,26 MB)
Gradivo ima več datotek! Več... |
47. Odpornost glioblastoma na radioterapijo : vpliv rakavih matičnih celic in mikroo[ko]lja tumorjaBarbara Breznik, Bernarda Majc, Anamarija Habič, Urška Ušeničnik, Andrej Porčnik, Roman Bošnjak, Jernej Mlakar, Marija Skoblar Vidmar, Tanja Jesenko, Maja Čemažar, Tamara Lah Turnšek, Metka Novak, 2022, objavljeni znanstveni prispevek na konferenci (vabljeno predavanje) Povzetek: Glioblastom je najpogostejši možganski tumor pri odraslih z zelo slabo prognozo preživetja bolnikov. Ta je posledica odpornosti glioblastoma na standardno zdravljenje, ki vključuje radioterapijo in kemoterapijo. Z namenom načrtovanja učinkovitejših pristopov zdravljenja preučujemo biološke mehanizme odpornosti glioblastoma na radioterapijo s poudarkom na mikrookolju tumorja in rakavih matičnih celicah. V predkliničnih raziskavah uporabljamo napredne in personalizirane celične modele, ki posnemajo mikrookolje tumorja v bolnikih in z večjo natančnostjo napovedo odziv bolnika na zdravljenje. Hkrati so takšni modeli pomembni za testiranje novih pristopov za zdravljenje kot je imunoterapija.
Ključne besede: glioblastom, mikrookolje, organoidi, možganski rak, možganski tumor, onkologija
Objavljeno v DiRROS: 16.06.2022; Ogledov: 610; Prenosov: 198
Celotno besedilo (89,78 KB) |
48. Artificial neural networks as an alternative method to nonlinear mixed-effects models for tree height predictionsMitja Skudnik, Jernej Jevšenak, 2022, izvirni znanstveni članek Povzetek: Tree heights are one of the most important aspects of forest mensuration, but data are often unavailable due to costly and time-consuming field measurements. Therefore, various types of models have been developed for the imputation of tree heights for unmeasured trees, with mixed-effects models being one of the most commonly applied approaches. The disadvantage here is the need of sufficient sample size per tree species for each plot, which is often not met, especially in mixed forests. To avoid this limitation, we used principal component analysis (PCA) for the grouping of similar plots based on the most relevant site descriptors. Next, we compared mixed-effects models with height-diameter models based on artificial neural networks (ANN). In terms of root mean square error (RMSE), mixed-effects models provided the most accurate tree height predictions at the plot level, especially for tree species with a smaller number of tree height measurements. When plots were grouped using the PCA and the number of observations per category increased, ANN predictions improved and became more accurate than those provided by mixed-effects models. The performance of ANN also increased when the competition index was included as an additional explanatory variable. Our results show that in the pursuit of the most accurate modelling approach for tree height predictions, ANN should be seriously considered, especially when the number of tree measurements and their distribution is sufficient.
Ključne besede: height-diameter models, national forest inventory, permanent sample plot, mixed forests, model comparison, principal component analysis
Objavljeno v DiRROS: 08.06.2022; Ogledov: 525; Prenosov: 221
 Povezava na datoteko |
49. Minimalno invazivni diagnostični pristopi pri primarnih možganskih tumorjih z uporabo prosto cirkulirajočih nukleinskih kislinMarija Skoblar Vidmar, Jernej Mlakar, Uroš Smrdel, Alenka Matjašič, Jože Pižem, Andrej Zupan, 2021, objavljeni znanstveni prispevek na konferenci Ključne besede: tekočinska biopsija, onkološko zdravljenje, možganski tumorji
Objavljeno v DiRROS: 04.04.2022; Ogledov: 610; Prenosov: 230
Celotno besedilo (123,97 KB) |
50. Priporočila za obravnavo bolnikov z rakom debelega črevesa in danke2020, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Ključne besede: rak debelega črevesa, rak danke, bolniki, zdravljenje
Objavljeno v DiRROS: 18.03.2022; Ogledov: 817; Prenosov: 441
Celotno besedilo (1,30 MB)
Gradivo ima več datotek! Več... |
