71. Consensus clinical scoring for suspected perioperative immediate hypersensitivity reactionsPhilip M. Hopkins, Peter J. Cooke, Russel C. Clarke, Anne Berit Guttormsen, Peter R. Platt, Pascale Dewachter, Didier G. Ebo, Tomaz Garcez, Lene Heise Garvey, David L. Hepner, Peter Kopač, 2019, izvirni znanstveni članek Povzetek: Background: Grading schemes for severity of suspected allergic reactions have been applied to the perioperative setting, but there is no scoring system that estimates the likelihood that the reaction is an immediate hypersensitivity reaction. Such a score would be useful in evaluating current and proposed tests for the diagnosis of suspected perioperative immediate hypersensitivity reactions and culprit agents. Methods: We conducted a Delphi consensus process involving a panel of 25 international multidisciplinary experts in suspected perioperative allergy. Items were ranked according to appropriateness (on a scale of 1-9) and consensus, which informed development of a clinical scoring system. The scoring system was assessed by comparing scores generated for a series of clinical scenarios against ratings of panel members. Supplementary scores for mast cell tryptase were generated. Results: Two rounds of the Delphi process achieved stopping criteria for all statements. From an initial 60 statements, 43 were rated appropriate (median score 7 or more) and met agreement criteria (disagreement index <0.5); these were used in the clinical scoring system. The rating of clinical scenarios supported the validity of the scoring system. Although there was variability in the interpretation of changes in mast cell tryptase by the panel, we were able to include supplementary scores for mast cell tryptase. Conclusion: We used a robust consensus development process to devise a clinical scoring system for suspected perioperative immediate hypersensitivity reactions. This will enable objectivity and uniformity in the assessment of the sensitivity of diagnostic tests. Ključne besede: alergy and immunology, anesthesia, anaphylaxis, drug hypersensitivity, drug-related side effects and adverse reactions, perioperative period, surgery, operative surgical procedures Objavljeno v DiRROS: 09.10.2020; Ogledov: 1765; Prenosov: 332 Povezava na datoteko |
72. Management of suspected immediate perioperative allergic reactions : an international overview and consensus recommendationsLene Heise Garvey, Pascale Dewachter, David L. Hepner, Paul Michel Mertes, Susanna Voltolini, Russel C. Clarke, Peter J. Cooke, Tomaz Garcez, Anne Berit Guttormsen, Didier G. Ebo, Philip M. Hopkins, Peter Kopač, 2019, pregledni znanstveni članek Povzetek: Suspected perioperative allergic reactions are rare but can be life-threatening. The diagnosis is difficult to make in the perioperative setting, but prompt recognition and correct treatment is necessary to ensure a good outcome. A group of 26 international experts in perioperative allergy (anaesthesiologists, allergists, and immunologists) contributed to a modified Delphi consensus process, which covered areas such as differential diagnosis, management during and after anaphylaxis, allergy investigations, and plans for a subsequent anaesthetic. They were asked to rank the appropriateness of statements related to the immediate management of suspected perioperative allergic reactions. Statements were selected to represent areas where there is a lack of consensus in existing guidelines, such as dosing of epinephrine and fluids, the management of impending cardiac arrest, and reactions refractory to standard treatment. The results of the modified Delphi consensus process have been included in the recommendations on the management of suspected perioperative allergic reactions. This paper provides anaesthetists with an overview of relevant knowledge on the immediate and postoperative management of suspected perioperative allergic reactions based on current literature and expert opinion. In addition, it provides practical advice and recommendations in areas where consensus has been lacking in existing guidelines. Ključne besede: allergy and immunology, drug hypersensitivity, anesthesia, drug-related side effects and adverse reactions, anaphylaxis, epinephrine, Delphi technique, perioperative period, allergic reactions, hypersensitivity reaction, adrenaline, perioperative anaphylaxis, allergy testing, guideline Objavljeno v DiRROS: 09.10.2020; Ogledov: 1390; Prenosov: 424 Povezava na datoteko |
73. Worldwide perspectives on venom allergyPeter Korošec, Thilo Jakob, Harfi Harb, Robert Heddle, Sarah Karabus, Ricardo de Lima Zollner, Julij Šelb, Bernard Yu-Hor Thong, Fares Zaitoun, David B. K. Golden, Michael Levin, 2019, pregledni znanstveni članek Povzetek: Venom immunotherapy is the standard of care for people with severe reactions and has been proven to reduce risk of future anaphylactic events. There is a moral imperative to ensure production, supply and worldwide availability of locally relevant, registered, standardized commercial venom extracts for diagnosis and treatment. Insects causing severe immediate allergic reactions vary by region worldwide. The most common culprits include honeybees (Apis mellifera), social wasps including yellow jackets (Vespula and Dolichovespula), paper wasps (Polistes) and hornets (Vespa), stinging ants (Solenopsis, Myrmecia, Pachycondyla, and Pogonomyrmex), and bumblebees (Bombus). Insects with importance in specific areas of the world include the Australian tick (Ixodes holocyclus), the kissing bug (Triatoma spp), horseflies (Tabanus spp), and mosquitoes (Aedes, Culex, Anopheles). Reliable access to high quality venom immunotherapy to locally relevant allergens is not available throughout the world. Many current commercially available therapeutic vaccines have deficiencies, are not suitable for, or are unavailable in vast areas of the globe. New products are required to replace products that are unstandardized or inadequate, particularly whole-body extract products. New products are required for insects in which no current treatment options exist. Venom immunotherapy should be promoted throughout the world and the provision thereof be supported by health authorities, regulatory authorities and all sectors of the health care service. Ključne besede: allergy and immunology, venoms, Hymenoptera, bee venoms, wasp venoms, insecta, ants hornet, bumblebee, mosquitoes, venom immunotherapy, immunologic desensitization Objavljeno v DiRROS: 23.09.2020; Ogledov: 1769; Prenosov: 1054 Celotno besedilo (313,42 KB) Gradivo ima več datotek! Več... |
74. Quantitative determination of PA6 and/or PA66 content in polyamide-containing wastesEma Žagar, Urška Češarek, Ana Drinčić, Simona Sitar, Igor Shlyapnikov, David Pahovnik, 2020, izvirni znanstveni članek Ključne besede: polymer waste, chemical recycling, microwave chemistry, polyamide content, liquid chromatography Objavljeno v DiRROS: 29.07.2020; Ogledov: 1640; Prenosov: 1198 Celotno besedilo (1,48 MB) Gradivo ima več datotek! Več... |
75. Kanabinoidi in medicinska konoplja v Sloveniji : zakonodaja, znanost in praksa v mediciniJožica Červek, David Neubauer, Milan Krek, Matej Červek, 2015, objavljeni strokovni prispevek na konferenci Ključne besede: medicinska konoplja, Slovenija, kanabinoidi, zakonodaja, medicina Objavljeno v DiRROS: 15.06.2020; Ogledov: 2047; Prenosov: 598 Celotno besedilo (150,16 KB) |
76. Ocena zgradbe in stabilnosti gozdnega roba kot pripomoček za ovrednotenje klimatske in zaščitne funkcije primestnih gozdovDavid Hladnik, Andrej Kobler, Janez Pirnat, 2020, izvirni znanstveni članek Povzetek: V prispevku podajamo razširjen povzetek iz članka, objavljenega v reviji Forests z naslovom Evaluation of forest edge structure and stability in peri-urban forests (Hladnik in sod., 2020). Dodali smo predloge o prenovi varovalne, zaščitne in klimatske funkcije gozdov ter predloge ukrepov, ki izhajajo iz izsledkov raziskave gozdnih robov. Analizirali smo vertikalno zgradbo gozdnih robov in opozorili na pomen dimenzijskega razmerja dreves h/d na gozdnih robovih primestnih gozdnih zaplat ob Ljubljani, kjer ob pozidanih zemljiščih prevladujejo visoki in strmi gozdni robovi. Predstavili smo preprosto metodologijo, na podlagi katere je mogoče z metodami daljinskega zbiranja podatkov zasnovati monitoring primestnih gozdnih površin in gozdnih robov. Ključne besede: funkcije gozdov, stabilnost gozdnega roba, gozdni rob, zgradba gozdnega roba, LiDAR, urbani gozdovi Objavljeno v DiRROS: 09.06.2020; Ogledov: 2291; Prenosov: 748 Celotno besedilo (296,57 KB) |
77. Evaluation of forest edge structure and stability in peri-urban forestsDavid Hladnik, Andrej Kobler, Janez Pirnat, 2020, izvirni znanstveni članek Povzetek: In the presented research, we studied the forest edge structure of urban and peri-urban forests on the outskirts of Ljubljana (Slovenia) consisting of a number of patches covering the collective surface of 1884 ha. They differ from each other according to the degree of fragmentation and by the share of the interior forest area. On the basis of LiDAR data, we conducted an analysis of the edges of the persistent forest patches and estimated them with regard to the land use they bordered on. The horizontal estimation of forest edges and the changes of forest edges, in the last decades, were estimated using digital orthophoto images of cyclic aerial surveys of Slovenia, from 1975 to 2018. The data, provided by LiDAR, were used to obtain an accurate estimate of forest edges and the metrics of their vertical canopy structure. On the basis of the canopy height model (CHM), we determined the height classes, the heights of the tallest trees, and indices of canopy height diversity (CHD) as variables subjected to a k-means cluster analysis. To determine the forest edge and trees stability, their heights and diameters at breast height (DBH) were measured and their canopy length and h/d (height/diameter) dimension ratios were estimated. In the study area of the Golovec forest patch, more than half of the forest edge segments (56%) border on residential buildings. After the construction of buildings, 54% of the newly formed forest edges developed a high and steep structure. Unfavorable h/d dimension ratio was estimated for 16% of trees, more among the coniferous than among the deciduous trees. Similar characteristics of newly formed forest edges bordering on built-up areas were determined in other sub-urban forest patches, despite the smaller share of such forest edges (19% and 10%, respectively). Tools and methods presented in the research enable the implementation of concrete silvicultural practices in a realistic time period and extend to ensure that adequate forestry measures are taken to minimize possible disturbances. Ključne besede: forest ecosystem services, forest edge stability, forest edge structure, LiDAR, urban forests Objavljeno v DiRROS: 26.05.2020; Ogledov: 1895; Prenosov: 1031 Celotno besedilo (5,67 MB) Gradivo ima več datotek! Več... |
78. Parameters for discrimination between organic and conventional production : a case study for chicory plants (Cichorium intybus L.)Lovro Sinkovič, Marijan Nečemer, Nives Ogrinc, Dragan Žnidarčič, David Stopar, Rajko Vidrih, Vladimir Meglič, 2020, izvirni znanstveni članek Ključne besede: Organic production, Conventional production, Chicory plant, Bioactive compounds, Fertility management, Isotopic signature, Multi-elemental profile, Nitrogen assimilation Objavljeno v DiRROS: 11.05.2020; Ogledov: 2437; Prenosov: 932 Celotno besedilo (1,83 MB) |
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80. Spletna anketa projekta ValoFor o odnosu lastnikov malih gozdnih posesti do gospodarjenja z gozdomUrša Vilhar, Mitja Skudnik, Katja Kavčič Sonnenschein, David Štefanič, Matevž Triplat, Hojka Kraigher, 2020, poljudni članek Ključne besede: lastniki gozdov, mala gozdna posest, projekt ValoFor Objavljeno v DiRROS: 02.05.2020; Ogledov: 2133; Prenosov: 718 Celotno besedilo (66,12 KB) |