91. The effect of olive fruit fly Bactrocera oleae (Rossi) infestation on certain chemical parameters of produced olive oilsVasilij Valenčič, Bojan Butinar, Maja Podgornik, Milena Bučar-Miklavčič, 2021, izvirni znanstveni članek Povzetek: Olives affected by active and damaging infestation (olive fruit fly Bactrocera oleae (Rossi)) were assayed for their chemical composition. Biophenols were determined by HPLC, sterols, triterpenic dialcohols, and fatty acids by gas chromatography analysis. The acquired data were statistically analyzed. Oils produced from "Istrska belica" fruit affected by active infestation compared to the oils made from fruit affected by damaging infestation showed higher amounts of total oleuropein biofenols (377.3 versus (vs.) 106.6 mg/kg), total biophenols (755 vs. 377 mg/kg), lignans (85.3 vs. 32.9mg/kg), the dialdehydic formof decarboxymethyl oleuropein aglycone (DMO-AgldA) (148.3 vs. 49.0 mg/kg), its oxidized form (DMO-Agl-dA)ox (35.2 vs. 8.5 mg/kg), the dialdehydic form of oleuropein aglycone (O-Agl-dA) (61.1 vs. 8.0 mg/kg), the dialdehydic form of ligstroside aglycone (L-Agl-dA) (63.5 vs. 28.0 mg/kg), the aldehydic form of oleuropein aglycone (O-Agl-A) (40.6 vs. 8.4 mg/kg), and lower amounts of tyrosol (Tyr) (6.0 vs. 13. 9 mg/kg) and the aldehydic form of ligstroside aglycone (L-Agl-A) (13.8 vs. 40.3 mg/kg). Higher values of stigmasterol (2.99%) and lower values of campesterol (2.25%) were determined in oils affected by damaging infestation; an increase in triterpenic dialcohols was also observed (3.04% for damaging and 1.62% for active infestation). Oils affected by damaging infestation, compared to active infestation, showed lower amounts of oleic acid (73.89 vs. 75.15%) and higher amounts of myristic (0.013 vs. 0.011%), linoleic (7.27 vs. 6.48%), and linolenic (0.74 vs. 0.61%) acids.
Ključne besede: olives, Istrska belica, olive fruit fly, biophenols, sterols, triterpenic dialcohols, fatty acids
Objavljeno v DiRROS: 13.01.2021; Ogledov: 1205; Prenosov: 1079
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92. Cabbage and fermented vegetables : from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19Jean Bousquet, Josep M. Antò i Boquè, Wienczyslawa Czarlewski, Tari Haahtela, Susana C. Fonseca, Guido Laccarino, Hubert Blain, Alain Vidal, Aziz Sheikh, Cezmi A. Akdis, Torsten Zuberbier, Samo Kreft, Klemen Jenko, Maja Jošt, Peter Kopač, Mitja Košnik, Karmen Kramer Vrščaj, Bojan Madjar, Davor Plavec, Tanja Soklič, Jure Urbančič, Mihaela Zidarn, 2020, izvirni znanstveni članek Povzetek: Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage were associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin converting enzyme 2 (ACE2). As a result of SARS-Cov-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1R) axis associated with oxidative stress. This leads to insulin resistanceas well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block the AT1R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are given: Kimchi in Korea, westernized foods and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects helpful in mitigating COVID-19 severity.
Ključne besede: COVID-19, diet, sulforaphane, Lactobacillus, Angiotensin converting enzyme 2, kimchi, cabbage, fermented vegetable
Objavljeno v DiRROS: 07.10.2020; Ogledov: 1393; Prenosov: 330
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94. Is diet partly responsible for differences in COVID-19 death rates between and within countries? : protocol for a systematic reviewJean Bousquet, Josep M. Antò i Boquè, Guido Laccarino, Wienczyslawa Czarlewski, Tari Haahtela, Aram Anto, Cezmi A. Akdis, Hubert Blain, Giorgio Walter Canonica, Karmen Kramer Vrščaj, Tari Haahtela, Mitja Košnik, Anja Koren, Peter Kopač, Maja Jošt, Samo Kreft, Klemen Jenko, Bojan Madjar, Davor Plavec, Tanja Soklič, Jure Urbančič, Mihaela Zidarn, 2020, pregledni znanstveni članek Povzetek: Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.
Ključne besede: coronavirus, diet, angiotensin-converting enzyme, antioxidant, food
Objavljeno v DiRROS: 09.09.2020; Ogledov: 1519; Prenosov: 1188
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95. Smernice za diagnostiko in zdravljenje bolnikov z rakom pljučJože Antonič, Tanja Bavčar-Vodovnik, Olga Cerar, Rok Cesar, Anton Crnjac, Andrej Debeljak, Majda Drnovšek, Janez Eržen, Matjaž Fležar, Jože Jerman, Maja Jerše, Peter Kecelj, Izidor Kern, Igor Kocijančič, Viljem Kovač, Nada Rotovnik-Kozjek, Karmen Kramer Vrščaj, Slavica Lahajnar, Ilonka Osrajnik, Tomaž Rott, Andreja A. Schwarzbartl-Pevec, Anja Simonič, Uroš Smrdel, Mihael Sok, Andreja Cirila Škufca Smrdel, Saša Štern, Marjeta Terčelj-Zorman, Nadja Triller, Matjaž Turel, Tomaž Varga, Bojan Veingerl, Barbara Vidergar-Kralj, Stanko Vidmar, Martina Vrankar, Vesna Zadnik, Branko Zakotnik, Jurij Zalar, Anton Zorko, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Objavljeno v DiRROS: 27.05.2020; Ogledov: 2134; Prenosov: 586
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100. Smernice za celostno rehabilitacijo bolnikov z rakom dojkNikola Bešić, Simona Borštnar, Teja Kovačec Hermann, Vesna Homar, Nataša Kos, Mateja Kurir-Borovčić, Tanja Marinko, Blanka Mikl Mežnar, Bojan Pelhan, Andreja Cirila Škufca Smrdel, Branka Stražišar, Tanja Španić, Metka Teržan, Lorna Zadravec-Zaletel, Irena Rahne Otorepec, Tamara Josimović, 2019, objavljeni strokovni prispevek na konferenci Ključne besede: rak dojk, celostna rehabilitacija, zdravljenje, bolniki
Objavljeno v DiRROS: 18.09.2019; Ogledov: 2953; Prenosov: 746
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