1. Prognostic factors of choroidal melanoma in Slovenia, 1986-2008Boris Jančar, Marjan Budihna, Brigita Drnovšek-Olup, Katrina Novak-Andrejčič, Irena-Hedvika Brovet-Zupančič, Dušica Pahor, 2016, izvirni znanstveni članek Povzetek: Introduction. Choroidal melanoma is the most common primary malignancy of the eye, which frequently metastasizes. The Cancer Registry of Slovenia reported the incidence of choroid melanoma from 1983 to 2009 as stable, at 7.8 cases/million for men and 7.4/million for women. The aim of the retrospective study was to determinate the prognostic factors of survival for choroidal melanoma patients in Slovenia. Patients and methods. From January 1986 to December 2008 we treated 288 patients with malignant choroidal melanoma; 127 patients were treated by brachytherapy with beta rays emitting ruthenium-106 applicators; 161 patients were treated by enucleation. Results. Patients with tumours thickness < 7.2 mm and base diameter < 16 mm were treated by brachytherapy and had 5- and 10-year overall mortality 13% and 32%, respectively. In enucleated patients, 5- and 10-year mortality was higher, 46% and 69%, respectively, because their tumours were larger. Thirty patients treated by brachytherapy developed local recurrence. Twenty five of 127 patients treated by brachytherapy and 86 of 161 enucleated patients developed distant metastases. Patients of age >/= 60 years had significantly lower survival in both treatment modalities. For patients treated by brachytherapy the diameter of the tumour base and treatment time were independent prognostic factors for overall survival, for patients treated by enucleation age and histological type of tumour were independent prognosticators. In first few years after either of treatments, the melanoma specific annual mortality rate increased, especially in older patients, and then slowly decreased. Conclusions. It seems that particularly younger patients with early tumours can be cured, whereby preference should be given to eyesight preserving brachytherapy over enucleation. Ključne besede: choroidal melanoma, therapy, brachytherapy, prognostic factors Objavljeno v DiRROS: 09.05.2024; Ogledov: 80; Prenosov: 43 Celotno besedilo (624,05 KB) Gradivo ima več datotek! Več... |
2. Revealing subtle active tectonic deformation: integrating lidar, photogrammetry, field mapping, and geophysical surveys to assess the Late Quaternary activity of the Sava Fault (Southern Alps, Slovenia)Petra Jamšek Rupnik, Jure Atanackov, Barbara Horn, Branko Mušič, Marjana Zajc, Christoph Grützner, Kamil Ustaszewski, Sumiko Tsukamoto, Matevž Novak, Blaž Milanič, Anže Markelj, Kristina Ivančič, Ana Novak, Jernej Jež, Manja Žebre, Miloš Bavec, Marko Vrabec, 2024, izvirni znanstveni članek Povzetek: We applied an interdisciplinary approach to analyze the late Quaternary activity of the Sava Fault in the Slovenian Southern Alps. The Sava Fault is an active strike-slip fault, and part of the Periadriatic Fault System that accommodated the convergence of Adria and Europe. It is one of the longest faults in the Southern Alps. Using high-resolution digital elevation models from lidar and photogrammetric surveys, we were able to overcome the challenges of assessing fault activity in a region with intense surface processes, dense vegetation, and relatively low fault slip rates. By integrating remote sensing analysis, geomorphological mapping, structural geological investigations, and near-surface geophysics (electrical resistivity tomography and ground penetrating radar), we were able to find subtle geomorphological indicators, detect near-surface deformation, and show distributed surface deformation and a complex fault pattern. Using optically stimulated luminescence dating, we tentatively estimated a slip rate of 1.8 ± 0.4 mm/a for the last 27 ka, which exceeds previous estimates and suggests temporal variability in fault behavior. Our study highlights the importance of modern high-resolution remote sensing techniques and interdisciplinary approaches in detecting tectonic deformation in relatively low-strain rate environments with intense surface processes. We show that slip rates can vary significantly depending on the studied time window. This is a critical piece of information since slip rates are a key input parameter for seismic hazard studies. Ključne besede: active fault, lidar, photogrammetry, tectonic geomorphology, structural geology, geophysics, electrical resistivity tomography, ground penetrating radar, slip rate, Sava Fault Objavljeno v DiRROS: 30.04.2024; Ogledov: 90; Prenosov: 47 Celotno besedilo (53,23 MB) |
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5. Pitna voda v Mestni občini Ljubljana : pot od vodnega vira do kozarcaTadeja Kosec, Nina Gartner, Brigita Jamnik, Viviana Golja, Alenka Labovič, Lucija Smojver, Sabina Dolenec, Aljoša Šajna, Monika Novak Babič, Nina Gunde-Cimerman, Tinkara Kopar, 2019, strokovna monografija Ključne besede: centralni vodovodni sistem Ljubljana (CVS), pitna voda, materiali v stiku s pitno vodo, vzdrževanje sistemov, preskušanje, kovinski materiali, organski materiali, cementni materiali, mikrobiološki vpliv, certificiranje proizvodov, vodno gospodarstvo, oskrba z vodo Objavljeno v DiRROS: 08.03.2024; Ogledov: 141; Prenosov: 64 Celotno besedilo (4,02 MB) Gradivo ima več datotek! Več... |
6. Small cellular particles from European spruce needle homogenateMarko Jeran, Anna Romolo, Vesna Spasovski, Matej Hočevar, Urban Novak, Roman Štukelj, Vid Šuštar, Matic Kisovec, Apolonija Bedina Zavec, Ksenija Kogej, Aleš Iglič, Polonca Trebše, Veronika Kralj-Iglič, 2023, izvirni znanstveni članek Ključne besede: Picea abies, spruce needles, extracellular particles, extracellular vesicles, small cellular particles, interferometric light microscopy, exosomes, cell-to-cell communication, drug delivery Objavljeno v DiRROS: 07.02.2024; Ogledov: 176; Prenosov: 115 Celotno besedilo (2,49 MB) Gradivo ima več datotek! Več... |
7. Insights into microstructural evolution of tungsten-tungsten carbide plasma facing composite materials prepared by field assisted sintering techniqueAljaž Iveković, Matej Kocen, Petra Jenuš, Anže Abram, Črtomir Donik, Saša Novak, 2023, izvirni znanstveni članek Ključne besede: tungsten, tungsten carbide, interface, microstructure, fusion energy Objavljeno v DiRROS: 07.02.2024; Ogledov: 158; Prenosov: 85 Celotno besedilo (14,95 MB) Gradivo ima več datotek! Več... |
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