Primer bolnika z nevrološkimi simptomi 11 let po zdravljenju karcinoma testisa

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Title:	Primer bolnika z nevrološkimi simptomi 11 let po zdravljenju karcinoma testisa
Authors:	ID Šoštarič Podlesnik, Marija (Author) ID Roš-Opaškar, Tanja (Author) ID Jereb, Berta (Author)
Files:	PDF - Presentation file, download (108,16 KB) MD5: 5CA4876E6DCA7B5116D29F1ECFB92CEA PID: 20.500.12556/dirros/619363e5-e97f-417f-b59b-6f402785bdd9
Language:	Slovenian
Typology:	1.04 - Professional Article
Organization:	OI - Institute of Oncology
Publication status:	Published
Publication version:	Version of Record
Year of publishing:	2010
Number of pages:	str. 161-162
Numbering:	Letn. 14, št. 2
PID:	20.500.12556/DiRROS-8947
UDC:	616.64/.68-006.6-08:616.83
ISSN on article:	1408-1741
URN:	URN:NBN:SI:doc-W6J44N8T
COBISS.SI-ID:	1057659
Copyright:	by Authors
Publication date in DiRROS:	31.08.2018
Views:	3105
Downloads:	807
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License:	CC BY 4.0, Creative Commons Attribution 4.0 International

Link:	http://creativecommons.org/licenses/by/4.0/
Description:	This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:	31.08.2018

Language:	English
Title:	The Patient with Neurologic Symptoms Appearing 11 Years after Treatment of Testicular Cancer
Abstract:	Introduction of cisplatin-based chemotherapy (ChT) improved the cure rate of patients with testicular cancer. Polyneuropathy, as the most common side effect of cisplatin, is observed in a high proportion of patients treated with PVB. Peripheral nerve damage of different grade, depending on the cumulative dose of the drug may last for many years after the conclusion of treatment. A large study on neuro-toxic symptoms in subjects treated with 6 cycles PVB is quoted. In the presented patient, neurologic symptoms appeared 11 years after the treatment with 3 cycles of PVB. The cause of his symptoms is not clear. Years ago, radiation was recognized as the most frequent cause of late effects, with chemotherapy recently increasing its role in this process. Careful life time follow-up by assorted specialists is necessary to gain further experience.