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Title:Priporočila za uporabo dejavnikov rasti granulocitne vrste pri bolnikih z rakom na sistemskem zdravljenju
Authors:ID Borštnar, Simona (Author)
ID Južnič Šetina, Tanja (Author)
Files:.pdf PDF - Presentation file, download (74,15 KB)
MD5: 64FB6F198D34E139D5849CD3F78B5807
PID: 20.500.12556/dirros/e9056fab-8246-4254-8c96-8d402379441a
 
Language:Slovenian
Typology:1.04 - Professional Article
Organization:Logo OI - Institute of Oncology
Abstract:Dejavniki rasti granulocitne vrste (G-CSF) so z rekombinantno DNK-tehnologijo pridobljeni naravni glikoproteini, ki spodbudijo dozorevanje belih krvničk. S preventivno uporabo G-CSF lahko preprečimo febrilno nevtropenijo (FN), ki je resen, življenje ogrožajoč neželeni učinek zdravljenja s citostatiki. Priporočamo jih, kadar je verjetnost febrilne nevtropenije 20-odstotna ali večja ali pa je tveganje za FN večje zaradi starosti in spremljajoče bolezni. G-CSF naj se ne uporabljajo rutinsko, če je febrilna nevtropenija že nastala. Njihovo mesto je še pri mobilizaciji krvotvornih perifernih matičnih celic, pri spodbudi rasti nevtrofilcev po alogeni ali avtologni presaditvi kostnega mozga in pri mielodisplastičnem sindromu (MDS).
Publication status:Published
Publication version:Version of Record
Year of publishing:2009
Number of pages:str. 16-18
Numbering:Letn. 13, št. 1
PID:20.500.12556/DiRROS-8929 New window
UDC:616-006
ISSN on article:1408-1741
URN:URN:NBN:SI:doc-IQ5LBH0F
COBISS.SI-ID:25689561 New window
Copyright:by Authors
Note:BSDOCID145199;
Publication date in DiRROS:31.08.2018
Views:3593
Downloads:775
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BORŠTNAR, Simona and JUŽNIČ ŠETINA, Tanja, 2009, Priporočila za uporabo dejavnikov rasti granulocitne vrste pri bolnikih z rakom na sistemskem zdravljenju. Onkologija [online]. 2009. Vol. 13, no. 1, p. 16–18. [Accessed 21 April 2025]. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=8929
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Record is a part of a journal

Title:Onkologija
Shortened title:Onkologija
Publisher:Onkološki inštitut
ISSN:1408-1741
COBISS.SI-ID:65324032 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:31.08.2018

Secondary language

Language:English
Title:Recommendations for the Use of Granulocyte Colony Stimulating Factors (G-CSFs) in Systemic Treatment of Cancer
Abstract:Granulocyte colony stimulating factors (G-CSFs) are natural glycoproteins produced by recombinant DNA technology, which stimulate the production of white blood cells. The use of G-CSFs could prevent febrile neutropenia (FN) which is a relatively frequent event in cancer patients treated with chemotherapy and is a potentially life-threatening situation. Primary G-CSF support is recommended in the patients with the overall FN risk ≥ 20% and in those who are at high risk for FN associated with age, medical history and disease characteristics. G-CSFs should not be routinely used in afebrile or febrile neutropenic patients. G-CSFs have a number of other indications, such as mobilization of peripheral blood stem cells, acceleration of neutrophil count recovery after allogeneic or autologous transplantation and in MDS.


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