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Title:Pomen retroperitonealne limfadenektomije pri zdravljenju neseminomskih tumorjev mod
Authors:ID Kmetec, Andrej (Author)
Files:.pdf PDF - Presentation file, download (198,61 KB)
MD5: B180AD2BA88B02757CC6074D24721C30
PID: 20.500.12556/dirros/cbb6e53c-1adc-4380-b6ad-680fbbcb2d3b
 
Language:Slovenian
Organization:Logo OI - Institute of Oncology
Abstract:V zadnjih letih je uspešna kemoterapija pri neseminomskih germinalnih tumorjih mod (NSGCT) zmanjšala pomen retroperitonealne limfadenektomije (RPLA). Kljub temu ima skoraj 30 % bolnikov po kemoterapiji še preostanek tumorja, kjer lahko v 60 % do 70 % histološko najdemo živo tumorsko tkivo. Merila, ki bi izključila potrebo po RPLA (zmanjšanje tumorja za več kot 90 %, negativni tumorski označevalci in preostanek tumorja manjši kot 2 cm), niso povsem zanesljiva, zato RPLA priporočajo tudi pri normalnih tumorskih označevalcih, če je preostanek tumorja večji kot 1 cm do 1,5 cm. Velikosti preostanka tumorja se je prilagodila tudi tehnika operacije, da bi tako zmanjšali pozne posledice operacije in izboljšali kakovost življenja bolnikov. Navadno naredimo enostransko ali enostransko razširjeno RPLA, le pri redkih bolnikih je možno narediti RPLA z ohranitvijo živcev. Pozna posledica operacije je predvsem retrogradna ejakulacija, vendar jo z enostransko RPLA lahko preprečimo pri 80 % bolnikov.
Keywords:rak (medicina), testisi, zdravljenje, limfadenektomija, kirurško zdravljenje
Publication status:Published
Publication version:Version of Record
Year of publishing:2010
Number of pages:str. 134-136, 169
Numbering:Letn. 14, št. 2
PID:20.500.12556/DiRROS-8781 New window
UDC:616.681-006-08
ISSN on article:1408-1741
URN:URN:NBN:SI:doc-FJKMQZR2
COBISS.SI-ID:290607616 New window
Copyright:by Authors
Publication date in DiRROS:31.08.2018
Views:3538
Downloads:882
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Record is a part of a journal

Title:Onkologija
Shortened title:Onkologija
Publisher:Onkološki inštitut
ISSN:1408-1741
COBISS.SI-ID:65324032 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:31.08.2018

Secondary language

Language:English
Title:The significance of retroperitoneal lymph node dissection in the treatment of non-seminomatous testicular tumors
Abstract:In the last years, effective chemotherapy in non-seminomatous germ cell tumors (NSGCT) diminished the significance of retroperitoneal lymph node dissection (RLND). Nearly 30% of patients have residual tumor after chemotherapy which harbor 60-70% of viable cancer and 30-40% of necrosis or fibrous tissue. The criteria to avoid RPLA, such as reduction of tumor volume by more than 90%, negative tumor markers and residual mass of less than 2 cm in size, are not sufficiently accurate. Postchemotherapy RPLND is recommended in the patients with normal tumor markers and residual tumor of the size ranging from 1-1.5 cm because of higher probability for active disease. According to tumor mass, considerable modifications in the technique of operation evolved to minimize late consequences of surgery and to improve quality of life. We perform one-side or one-side extended RPLND, while nerve-sparing surgery can be done only in specific patients. Late consequence is the retrograde ejaculation which can be prevented in 80% with unilateral RPLND.


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