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Naslov: Nove možnosti citopatološke diagnostike raka sečnega mehurja s testom UroVysion Avtorji: ID Strojan Fležar, Margareta (Avtor) ID Srebotnik-Kirbiš, Irena (Avtor) Datoteke: PDF - Predstavitvena datoteka, prenos (501,17 KB) MD5: 405065A75CAC0B105E564BC9D4BDC78E PID: 20.500.12556/dirros/332157d7-d06e-461c-92c1-6a74f542b07e   Jezik: Slovenski jezik Tipologija: 1.04 - Strokovni članek Organizacija: OI - Onkološki inštitut Ljubljana Ključne besede: sečni mehur, rak (medicina), citološka diagnostika Status publikacije: Objavljeno Verzija publikacije: Objavljena publikacija Leto izida: 2009 Št. strani: str. 130-132, 153 Številčenje: Letn. 13, št. 2 PID: 20.500.12556/DiRROS-8619  UDK: 616.62-006-07 ISSN pri članku: 1408-1741 URN: URN:NBN:SI:doc-9XB4AZO1 COBISS.SI-ID: 27082969  Avtorske pravice: by Authors Opomba: BSDOCID151741; Datum objave v DiRROS: 31.08.2018 Število ogledov: 3016 Število prenosov: 892 Metapodatki:    Citiraj gradivo Navadno besedilo BibTeX EndNote XML EndNote/Refer RIS ABNT ACM Ref AMA APA Chicago 17th Author-Date Harvard IEEE ISO 690 MLA Vancouver : Kopiraj citat

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Gradivo je del revije

Naslov:	Onkologija
Skrajšan naslov:	Onkologija
Založnik:	Onkološki inštitut
ISSN:	1408-1741
COBISS.SI-ID:	65324032

Licence

Licenca:	CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:	http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:	To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Začetek licenciranja:	31.08.2018

Sekundarni jezik

Jezik:	Angleški jezik
Naslov:	New Promises of Cytopathologic Diagnostics of Bladder cancer by Using UroVysion™
Povzetek:	Cytopathologic examination of the urine and bladder washing is a standard method for the detection of primary bladder cancer in symptomatic patients or in patients with hematuria. The method is also very useful to follow the patients after treatment in order to detect recurrence of bladder cancer which occurs in a significant percentage of patients. Cytopathologic examination is highly accurate for the diagnosis of high grade urothelial carcinoma and carcinoma in situ. However, the method is recognized as being unreliable for the detection of low grade urothelial neoplasms. Obvious cellular and nuclear morphological signs of malignancy can be reliably recognized in high grade papillary, invasive and in situ urothelial carcinoma. Thus, less pronounced cellular atypia pose everyday diagnostic problems and atypia of low grade papillary neoplasms cannot be always reliably differentiated from atypia of some benign and post-treatment reactive changes. In the last decade a number of new urinary markers have been developed to overcome low sensitivity of urinary cytology. Although most of these tests are highly sensitive, they have lower specificity than cytology. The UroVysion test seems the most promising among the new tests. By the method of multitarget fluorescent in situ hybridisation (FISH), the test can detect several cytogenetic changes characteristic for different grades of bladder cancer. Therefore, the UroVysion test is useful for assessing neoplastic nature of cytologically undetermined atypical cells. The most recent reports claim that the UroVysion test can even detect bladder cancer before morphological changes are diagnosed in urine cytology.

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