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Title:CRISPR/Cas-mediated plant genome editing : outstanding challenges a decade after implementation
Authors:ID Cardi, Teodoro (Author)
ID Murovec, Jana (Author)
ID Bakhsh, Allah (Author)
ID Galović, Vladislava (Author)
ID Lukan, Tjaša (Author)
ID Yıldırım, Kubilay (Author)
ID Zlatković, Milica (Author)
ID Van Laere, Katrijn (Author)
Files:URL URL - Source URL, visit https://www.cell.com/action/showPdf?pii=S1360-1385%2823%2900164-4
 
.pdf PDF - Presentation file, download (4,40 MB)
MD5: 8F76B958351D20986DDA9CD15E8DF917
 
URL URL - Source URL, visit https://doi.org/10.1016/j.tplants.2023.05.012
 
Language:English
Typology:1.02 - Review Article
Organization:Logo NIB - National Institute of Biology
Abstract:The discovery of the CRISPR/Cas genome-editing system has revolutionized our understanding of the plant genome. CRISPR/Cas has been used for over a decade to modify plant genomes for the study of specific genes and biosynthetic pathways as well as to speed up breeding in many plant species, including both model and non-model crops. Although the CRISPR/Cas system is very efficient for genome editing, many bottlenecks and challenges slow down further improvement and applications. In this review we discuss the challenges that can occur during tissue culture, transformation, regeneration, and mutant detection. We also review the opportunities provided by new CRISPR platforms and specific applications related to gene regulation, abiotic and biotic stress response improvement, and de novo domestication of plants.
Keywords:CRISPR applications, CRISPR platforms, gene regulations, mutant detection, plant regeneration
Publication status:Published
Publication version:Version of Record
Publication date:01.10.2023
Year of publishing:2023
Number of pages:Str. 1144-1165
Numbering:Vol. 28, iss. 10
PID:20.500.12556/DiRROS-20063 New window
UDC:60
ISSN on article:1360-1385
DOI:10.1016/j.tplants.2023.05.012 New window
COBISS.SI-ID:156416259 New window
Publication date in DiRROS:05.08.2024
Views:456
Downloads:383
Metadata:XML DC-XML DC-RDF
:
CARDI, Teodoro, MUROVEC, Jana, BAKHSH, Allah, GALOVIĆ, Vladislava, LUKAN, Tjaša, YILDIRIM, Kubilay, ZLATKOVIĆ, Milica and VAN LAERE, Katrijn, 2023, CRISPR/Cas-mediated plant genome editing : outstanding challenges a decade after implementation. Trends in Plant Science [online]. 2023. Vol. 28, no. 10, p. 1144–1165. [Accessed 6 April 2025]. DOI 10.1016/j.tplants.2023.05.012. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=20063
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Record is a part of a journal

Title:Trends in Plant Science
Shortened title:Trends plant sci.
Publisher:Elsevier Science
ISSN:1360-1385
COBISS.SI-ID:3735079 New window

Document is financed by a project

Funder:Other - Other funder or multiple funders
Funding programme:European Cooperation in Science and Technology
Project number:CA18111
Name:COST Action PlantEd

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

Language:Slovenian
Keywords:rastlinska genetika, aplikacije CRISPR, regulacija genov, mutanti, regeneracija rastlin


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