| Title: | Radiological assessment of skeletal muscle index and myosteatosis and their impact postoperative outcomes after liver transplantation |
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| Authors: | ID Petrič, Miha (Author)
ID Jordan, Taja (Author)
ID Popuri, Karteek (Author)
ID Ličen, Sabina (Author)
ID Trotovšek, Blaž (Author)
ID Tomažič, Aleš (Author) |
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| Files: |  URL - Source URL, visit https://doi.org/10.2478/raon-2023-0025
URL - Source URL, visit https://www.radioloncol.com/index.php/ro/article/view/4062/5150
 PDF - Presentation file, download (1,69 MB)
MD5: 0DF992716798DE1C4D664FFFB0024A21
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  OI - Institute of Oncology
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| Abstract: | Background. Liver transplantation offers curative treatment to patients with acute and chronic end-stage liver disease. The impact of nutritional status on postoperative outcomes after liver transplantation remains poorly under-stood. The present study investigated the predictive value of radiologically assessed skeletal muscle index (SMI) and myosteatosis (MI) on postoperative outcomes.Patients and methods. Data of 138 adult patients who underwent their first orthotopic liver transplantation were retrospectively analysed. SMI and MI in computer tomography (CT) scan at the third lumbar vertebra level were cal-culated. Results were analyzed for the length of hospitalisation and postoperative outcomes.Results. In 63% of male and 28.9% of female recipients, low SMI was found. High MI was found in 45(32.6%) patients. Male patients with high SMI had longer intensive care unit (ICU) stay (P < 0.025). Low SMI had no influence on ICU stay in female patients (P = 0.544), length of hospitalisation (male, P > 0.05; female, P = 0.843), postoperative complication rates (males, P = 0.883; females, P = 0.113), infection rate (males, P = 0.293, females, P = 0.285) and graft rejection (males, P = 0.875; females, P = 0.135). The presence of MI did not influence ICU stay (P = 0.161), hospitalization (P = 0.771), postoperative complication rates (P = 0.467), infection rate (P = 0.173) or graft rejection rate (P = 0.173).Conclusions. In our study, changes in body composition of liver transplant recipients observed with SMI and MI had no impact on postoperative course after liver transplantation. CT body composition analysis of recipients and uni-formly accepted cut-off points are crucial to producing reliable data in the future. |
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| Keywords: | muscle mass, liver transplantation, myosteatosis, skeletal muscle index, GLIM score |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Publication date: | 01.01.2023 |
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| Publisher: | Association of Radiology and Oncology |
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| Year of publishing: | 2023 |
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| Number of pages: | str. 168-177 |
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| Numbering: | Vol. 57, iss. 2 |
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| Source: | Ljubljana |
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| PID: | 20.500.12556/DiRROS-19836  |
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| UDC: | 616-089 |
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| ISSN on article: | 1318-2099 |
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| DOI: | 10.2478/raon-2023-0025 |
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| COBISS.SI-ID: | 159734019 |
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| Copyright: | by Authors |
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| Note: | Soavtorji: Kaja Jordan, Popuri Karteek, Sabina Licen, Blaz Trotovsek, Ales Tomazic;
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| Publication date in DiRROS: | 25.07.2024 |
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| Views: | 124 |
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| Downloads: | 171 |
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