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Naslov:Red blood cell transfusion and skeletal muscle tissue oxygenation in anaemic haematologic outpatients
Avtorji:ID Podbregar, Matej (Avtor)
ID Gavrič, Ana Uršula (Avtor)
ID Podbregar, Eva (Avtor)
ID Možina, Hugon (Avtor)
ID Stefanović, Sebastian (Avtor)
Datoteke:URL URL - Izvorni URL, za dostop obiščite http://www.degruyter.com/view/j/raon.ahead-of-print/raon-2015-0046/raon-2015-0046.xml
 
.pdf PDF - Predstavitvena datoteka, prenos (958,31 KB)
MD5: C501C910C0DEA689423DB8F27900ABED
 
Jezik:Angleški jezik
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:Logo OI - Onkološki inštitut Ljubljana
Povzetek:Background. Stored red blood cells (RBCs) accumulate biochemical and biophysical changes, known as storage lesion. The aim of this study was to re-challenge current data that anaemia in chronically anaemic haematology patients is not associated with low skeletal muscle tissue oxygen (StO2), and that RBC storage age does not influence the tissue response after ischaemic provocation, using near-infrared spectroscopy. Patients and methods. Twenty-four chronic anaemic haematology patients were included. Thenar skeletal muscle StO2 was measured at rest (basal StO2), with vascular occlusion testing (upslope StO2, maximum StO2) before and after transfusion. Results. Basal StO2 was low (53% +- 7%). Average RBC storage time was 10.5 +- 3.9 days. Effects of RBC transfusions were as follows: basal StO2 and upslope StO2 did not change significantly; maximum StO2 increased compared to baseline (64 +- 14% vs. 59 +- 10%, p = 0.049). Change of basal StO2, upslope StO2 and maximum StO2 was negatively related to age of RBCs. The decrease of maximum StO2 was predicted (sensitivity 70%, specificity 100%), after receiving RBCs >- 10days old. Discussion. Resting skeletal muscle StO2 in chronic anaemic patients is low. RBC storage time affects skeletal muscle StO2 in the resting period and after ischaemic provocation.
Ključne besede:skeletal muscle, transfusion, red blood cells
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Datum objave:01.12.2016
Založnik:Association of Radiology and Oncology
Leto izida:2016
Št. strani:str. 449-455, X
Številčenje:Vol. 50, no. 4
Izvor:Ljubljana
PID:20.500.12556/DiRROS-18898 Novo okno
UDK:615.38:616.155.1
ISSN pri članku:1318-2099
DOI:10.1515/raon-2015-0046 Novo okno
COBISS.SI-ID:32508889 Novo okno
Avtorske pravice:by Authors
Opomba:Soavtorji: Ana Ursula Gavric, Eva Podbregar, Hugon Mozina, Sebastian Stefanovic;
Datum objave v DiRROS:09.05.2024
Število ogledov:454
Število prenosov:272
Metapodatki:XML DC-XML DC-RDF
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Gradivo je del revije

Naslov:Radiology and oncology
Skrajšan naslov:Radiol. oncol.
Založnik:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 Novo okno

Sekundarni jezik

Jezik:Slovenski jezik
Ključne besede:skeletne mišice, oksigenacija, transfuzija, eritrociti


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