Digital repository of Slovenian research organisations

Show document
A+ | A- | Help | SLO | ENG

Title:Mesenteric ischemia after capecitabine treatment in rectal cancer and resultant short bowel syndrome is not an absolute contraindication for radical oncological treatment
Authors:ID Perpar, Ana (Author)
ID Brecelj, Erik (Author)
ID Rotovnik-Kozjek, Nada (Author)
ID Anderluh, Franc (Author)
ID Oblak, Irena (Author)
ID Skoblar Vidmar, Marija (Author)
ID Velenik, Vaneja (Author)
Files:.pdf PDF - Presentation file, download (557,53 KB)
MD5: 1A15A6F4BB9855DE2BA23283D76C17A1
 
Language:English
Typology:1.03 - Other scientific articles
Organization:Logo OI - Institute of Oncology
Abstract:Thrombotic events, arterial or venous in origin, still remain a source of substantial morbidity and mortality in cancer patients. The propensity for their development in oncology patients is partially a consequence of the disease itself and partially a result of our attempts to treat it. One of the rarest and deadliest thromboembolic complications is arterial mesenteric ischemia. The high mortality rate is caused by its rarity and by its non-specific clinical presentation, both of which make early diagnosis and treatment difficult. Hence, most diagnoses and treatments occur late in the course of the disease. The issue survivors of arterial mesenteric ischemia may face is short bowel syndrome, which has become a chronic condition after the introduction of parenteral nutrition at home. We present a 73-year-old rectal cancer patient who developed acute arterial mesenteric thrombosis at the beginning of the pre-operative radiochemotherapy. Almost the entire length of his small intestine, except for the proximal 50 cm of it, and the ascending colon had to be resected. After multiorgan failure his condition improved, and he was able to successfully complete radical treatment (preoperative radiotherapy and surgery) for the rectal carcinoma, despite developing short bowel syndrome (SBS) and being dependent upon home-based parenteral nutrition to fully cover his nutritional needs. Mesenteric ischemia and resultant short bowel syndrome are not absolute contraindications for radical oncological treatment since such patients can still achieve long-term remission.
Keywords:acute mesenteric ischemia, capecitabine, multiorgan failure, rectal cancer, short bowel syndrome
Publication status:Published
Publication version:Version of Record
Publication date:01.06.2015
Publisher:Association of Radiology and Oncology
Year of publishing:2015
Number of pages:str. 181-184, VII
Numbering:Vol. 49, no. 2
Source:Ljubljana
PID:20.500.12556/DiRROS-18808 New window
UDC:616.351-006-005.4-08
ISSN on article:1318-2099
DOI:10.2478/raon-2014-0024 New window
COBISS.SI-ID:281458176 New window
Copyright:by Authors
Publication date in DiRROS:23.04.2024
Views:710
Downloads:187
Metadata:XML DC-XML DC-RDF
:
PERPAR, Ana, BRECELJ, Erik, ROTOVNIK-KOZJEK, Nada, ANDERLUH, Franc, OBLAK, Irena, SKOBLAR VIDMAR, Marija and VELENIK, Vaneja, 2015, Mesenteric ischemia after capecitabine treatment in rectal cancer and resultant short bowel syndrome is not an absolute contraindication for radical oncological treatment. Radiology and oncology [online]. 2015. Vol. 49, no. 2, p. 181–184, vii. [Accessed 10 April 2025]. DOI 10.2478/raon-2014-0024. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=18808
Copy citation
  
Share:Bookmark and Share


Hover the mouse pointer over a document title to show the abstract or click on the title to get all document metadata.

Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:Slovenian
Keywords:rak (medicina), danka, rak danke, zdravljenje, ishemija mezenterija, sindrom kratkega črevesa, zapleti


Back