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Title:Consequence of the introduction of routine FCH PET/CT imaging for patients with prostate cancer : a dual centre survey
Authors:ID Hodolič, Marina (Author)
ID Michaud, Laure (Author)
ID Huchet, V. (Author)
ID Balogova, S. (Author)
ID Nataf, V. (Author)
ID Kerrou, K. (Author)
ID Vereb, M. (Author)
ID Fettich, Jurij (Author)
ID Talbot, Jean-Noël (Author)
Files:URL URL - Source URL, visit http://www.degruyter.com/view/j/raon.ahead-of-print/raon-2013-0049/raon-2013-0049.xml
 
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Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo OI - Institute of Oncology
Abstract:Background. Fluorocholine(18F) (FCH) was introduced at the beginning of April 2010 in France, Slovenia and three other EU member states for the localisation of bone metastases of prostate cancer with PET. The aim of the study was to compare the evolution of diagnostic imaging in patients with prostate cancer using a new radiopharmaceutical FCH, observed in France and in Slovenia, and to quantify the consequence of the results of new imaging modality on the detection rate of abnormal metastases and recurrences of prostate cancer.Patients and methods. In two centres (France/Slovenia), a survey of the number of nuclear medicine examinations in patients with prostate cancer was performed, covering 5 quarters of the year since the introduction of FCH. For each examination, the clinical and biological circumstances were recorded, as well as the detection of bone or soft tissue foci.Results. Six hundred and eighty-eight nuclear medicine examinations were performed impatients with prostate cancer. Nuclear medicine examinations were performed for therapy monitoring and follow-up in 23% of cases. The number of FCH PET/CT grew rapidly between the 1st and 5th period of the observation (+220%), while the number of bone scintigraphies (BS) and fluoride(18F) PET/CTs decreased (-42% and -23% respectively). Fluorodeoxyglucose(18F) (FDG) PET/CT remained limited to few cases of castrate-resistant or metastatic prostate cancer in Paris. The proportion of negative results was significantly lower with FCH PET/CT (14%) than with BS (49%) or fluoride(18F) PET/CT (54%). For bone metastases, the detection rate was similar, but FCH PET/CT was performed on average at lower prostate-specific antigen (PSA) levels and was less frequently doubtful (4% vs. 28% for BS). FCH PET/CT also showed foci in prostatic bed (53% of cases) or in soft tissue (35% of cases).Conclusions. A rapid development of FCH PET/CT was observed in both centres and led to a higher detection rate of prostate cancer lesions.
Keywords:prostate cancer, PET/CT, fluorocholine (FCH), fluoride(18F), bone scintigraphy, indication of imaging, prostata, rak (medicina), slikovna diagnostika
Publication status:Published
Publication version:Version of Record
Publication date:01.03.2014
Publisher:Association of Radiology and Oncology
Year of publishing:2014
Number of pages:str. 20-28
Numbering:Vol. 48, no. 1
Source:Ljubljana
PID:20.500.12556/DiRROS-18614 New window
UDC:616.65-006-07
ISSN on article:1318-2099
DOI:10.2478/raon-2013-0049 New window
COBISS.SI-ID:1067180 New window
Copyright:by Authors
Publication date in DiRROS:04.04.2024
Views:1015
Downloads:719
Metadata:XML DC-XML DC-RDF
:
HODOLIČ, Marina, MICHAUD, Laure, HUCHET, V., BALOGOVA, S., NATAF, V., KERROU, K., VEREB, M., FETTICH, Jurij and TALBOT, Jean-Noël, 2014, Consequence of the introduction of routine FCH PET/CT imaging for patients with prostate cancer : a dual centre survey. Radiology and oncology [online]. 2014. Vol. 48, no. 1, p. 20–28. [Accessed 8 April 2025]. DOI 10.2478/raon-2013-0049. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=18614
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

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