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Title: Vloga radioterapije pri oligometastatskih gastrointestinalnih rakih Authors: ID Korošec, Peter (Author) Files: PDF - Presentation file, download (84,10 KB) MD5: 523224335ADA8FE456956A33E6ED8AA1   Language: Slovenian Typology: 1.08 - Published Scientific Conference Contribution Organization: OI - Institute of Oncology Abstract: Zdravljenje s stereotaktično radioterapijo (SBRT) se je v zadnjih letih tudi pri oligometastatskem gastrointestinalnem raku izkazalo za eno izmed pomembnejših možnosti lokalnega ablativnega zdravljenja, ki izboljšuje tako lokalno kontrolo, preživetje brez bolezni, kot tudi celokupno preživetje. Ob tem pa se je stereotaktično obsevanje izkazalo za varno metodo. Glede na lokacijo zasevkov so najpogosteje obsevani zasevki v jetrih in pljučih. Zaradi višje radiorezistentence zasevkov je potrebna večja izsevana doza (BED ≥ 100 Gy). Za čim manj stranskih učinkov pa je potrebna uporaba sistemov, ki zmanjšujejo gibanje tarče in povečujejo natančnost obsevanja. Večina dokazov do sedaj sicer temelji na retrospektivnih analizah in manjših prospektivnih študijah faze I in II. Rezultati prospektivnih študij faze III pa nam bodo v prihodnosti potrdili kdaj in kateri pacienti bodo imeli od zdravljenja z obsevanjem največjo korist. Keywords: gastrointestinalni rak, radioterapija, rak prebavil Publication status: Published Publication version: Version of Record Place of publishing: Ljubljana Publisher: Onkolološki inštitut Year of publishing: 2022 Number of pages: Str. 83-85 PID: 20.500.12556/DiRROS-16062  UDC: 616.3 COBISS.SI-ID: 135692291  Copyright: by Author Note: Nasl. z nasl. zaslona; Opis vira z dne 29. 12. 2022; Publication date in DiRROS: 13.01.2023 Views: 817 Downloads: 189 Metadata:    Cite this work Plain text BibTeX EndNote XML EndNote/Refer RIS ABNT ACM Ref AMA APA Chicago 17th Author-Date Harvard IEEE ISO 690 MLA Vancouver : Copy citation

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Record is a part of a monograph

Title:	Tumorji prebavil : Standardi in perspektive
Editors:	Marko Boc, Tanja Mesti
Place of publishing:	Ljubljana
Publisher:	Onkološki inštitut, Sekcija za internistično onkologijo, Katedra za onkologijo
Year of publishing:	2022
ISBN:	978-961-7029-55-0
COBISS.SI-ID:	133694211

Secondary language

Language:	English
Title:	The role of radiotherapy in oligometastatic gastrointestinal cancers
Abstract:	In recent years, treatment with stereotactic radiotherapy (SBRT) has proven to be one of the most important local ablative treatment options for oligometastatic gastrointestinal cancer, which improves both local control, disease-free survival, and overall survival. However, stereotactic radiation has proven to be a safe method. Depending on the location of the nodules, the most frequently irradiated nodules are in the liver and lungs. A higher radiation dose (BED ≥ 100 Gy) is required due to the higher radioresistance of the metastases. In order to minimize side effects, it is necessary to use systems that reduce the movement of the target and increase the accuracy of irradiation. Most of the evidence so far is based on retrospective analyzes and smaller prospective phase I and II studies. The results of prospective phase III studies will confirm in the future when and which patients will benefit the most from radiation treatment.

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