| Naslov: | Mixed results with baricitinib in biological-resistant adult-onset Still's disease and undifferentiated systemic autoinflammatory disease |
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| Avtorji: | ID Kačar, Mark, Klinika Golnik (Avtor)
ID Fitton, John (Avtor)
ID Gough, Andrew K (Avtor)
ID Buch, Maya H (Avtor)
ID McGonagle, Dennis (Avtor)
ID Savic, Sinisa (Avtor) |
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| Datoteke: |  PDF - Predstavitvena datoteka, prenos (321,22 KB)
MD5: 0EA382F8C02ADAF3AF616620A6889371
 URL - Izvorni URL, za dostop obiščite https://rmdopen.bmj.com/content/rmdopen/6/2/e001246.full.pdf
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| Jezik: | Angleški jezik |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: |  UKPBAG - Univerzitetna klinika za pljučne bolezni in alergijo Golnik
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| Povzetek: | This clinical case series describes our experience with the use of Janus kinase 1/2 inhibitor baricitinib in two patients suffering from refractory adult-onset Still's disease (AOSD) as well as in one case suffering from AOSD-like autoinflammatory disease in the context of myelodysplastic syndrome. All patients suffered from disease nonresponsive to conventional Disease-modifying antirheumatic drugs (DMARDs) as well as biological therapies including interleukin (IL)-1 and IL-6 blockade, relying instead on high daily doses of prednisolone. We also report the first case of Pneumocystis jirovecii infection following baricitinib use. |
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| Ključne besede: | adult onset Still's disease -- drug therapy, ankylosing spondylitis, arthritis, antirheumatic agents, undifferentiated systemic autoinflammatory disease, disease-modifying antirheumatic drugs |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Kraj izida: | Velika Britanija |
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| Založnik: | BMJ Publishing |
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| Leto izida: | 2020 |
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| Št. strani: | str. 1-5 |
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| Številčenje: | Vol. 6, iss. 2 |
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| PID: | 20.500.12556/DiRROS-13872  |
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| UDK: | 616-002 |
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| ISSN pri članku: | 2056-5933 |
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| DOI: | 10.1136/ rmdopen-2020-001246 |
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| COBISS.SI-ID: | 58397187 |
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| Avtorske pravice: | © Author(s) (or their employer(s)) 2020. |
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| Opomba: | Nasl. z nasl. zaslona;
Opis vira z dne 6. 4. 2021;
Št. članka: e001246;
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| Datum objave v DiRROS: | 08.04.2021 |
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| Število ogledov: | 1678 |
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| Število prenosov: | 1008 |
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| Metapodatki: |    |
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