1. Mesenteric ischemia after capecitabine treatment in rectal cancer and resultant short bowel syndrome is not an absolute contraindication for radical oncological treatmentAna Perpar, Erik Brecelj, Nada Rotovnik-Kozjek, Franc Anderluh, Irena Oblak, Marija Skoblar Vidmar, Vaneja Velenik, 2015, short scientific article Abstract: Thrombotic events, arterial or venous in origin, still remain a source of substantial morbidity and mortality in cancer patients. The propensity for their development in oncology patients is partially a consequence of the disease itself and partially a result of our attempts to treat it. One of the rarest and deadliest thromboembolic complications is arterial mesenteric ischemia. The high mortality rate is caused by its rarity and by its non-specific clinical presentation, both of which make early diagnosis and treatment difficult. Hence, most diagnoses and treatments occur late in the course of the disease. The issue survivors of arterial mesenteric ischemia may face is short bowel syndrome, which has become a chronic condition after the introduction of parenteral nutrition at home. We present a 73-year-old rectal cancer patient who developed acute arterial mesenteric thrombosis at the beginning of the pre-operative radiochemotherapy. Almost the entire length of his small intestine, except for the proximal 50 cm of it, and the ascending colon had to be resected. After multiorgan failure his condition improved, and he was able to successfully complete radical treatment (preoperative radiotherapy and surgery) for the rectal carcinoma, despite developing short bowel syndrome (SBS) and being dependent upon home-based parenteral nutrition to fully cover his nutritional needs. Mesenteric ischemia and resultant short bowel syndrome are not absolute contraindications for radical oncological treatment since such patients can still achieve long-term remission.
Keywords: acute mesenteric ischemia, capecitabine, multiorgan failure, rectal cancer, short bowel syndrome
Published in DiRROS: 23.04.2024; Views: 4; Downloads: 2
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2. Lymphedema following cancer therapy in Slovenia : a frequently overlooked condition?Tanja Planinšek Ručigaj, Nada Kecelj, Vesna Tlaker Žunter, 2010, original scientific article Abstract: Introduction. Secondary lymphedema following cancer therapy is a frequent, often painful, quality of life disturbing condition, reducing the patients' mobility and predisposing them to complications, e.g. infections and malignancies. The critical aspect of lymphedema therapy is to start as soon aspossible to prevent the irreversible tissue damage. Patients and methods. Weperformed a retrospective study of patients with lymphedema, treated at the Department of Dermatovenereology, University Medical Center Ljubljana, from January 2002 to June 2010. The patientsć demographic and medical data were collected, including type of cancer, type and stage of lymphedema, and time tofirst therapy of lymphedema. The number of referred patients with lymphedema following the therapy of melanoma, breast cancer, and uterine/cervical cancer, was compared to the number of patients expected to experience lymphedema following cancer therapy, calculated from the incidence reported in the literature. Results. In the period of 8.5 years, 543 patients (432 females, 112 males) with lymphedema were treated. The results show that probably many Slovenian patients with secondary lymphedema following cancer therapy remain unrecognized and untreated or undertreated. In the majority of our patients, the management of lymphedema was delayedč on average, the patients first received therapy for lymphedema 3.6 years after the first signsof lymphedema. Conclusions. To avoid a delay in diagnosis and therapy, and the complications of lymphedema following cancer therapy, the physician should actively look for signs or symptoms of lymphedema during the follow-up period, and promptly manage or refer the patients developing problems.
Keywords: rak (medicina), zdravljenje, limfedem
Published in DiRROS: 18.03.2024; Views: 80; Downloads: 29
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3. Influence of UV-B radiation on Norway spruce seedlings (Picea abies (L.) Karst.)Jože Bavcon, Nada Gogala, Alenka Gaberščik, 1998, original scientific article Abstract: On the basis of the hypothesis that the ultraviolet radiation is one of the main causes for damage at higher altitudes, we have monitored the effect of UVradiation on Norway spruce for two and a half years. The influence of UV-B radiation on Picea abies (L). Karst.seedlings cultured in pots in open greenhouses was examined by measuring photochemical efficiency of photosystem II, changes in chlorophyll a, b, and changes in anthocyanins. The seedlings were grown in a mixture of peat and vermiculite (4:1). We used Osram ultravitaluks bulbs as a source of UV-B radiation. In the experiment plants were treated with 21.24+-3.5 kJ/m2 and 31.9+-2.5 KJ/m2. The control plants were grown under ambient conditions in the greenhouse without artificial source of UV-B radiation. The mean yearly values were as high as 11.5+-5.2 kJ/m2. The photochemical efficiency of photosystem II (PS II) in experimental plants did not vary during the experiment. It showed obvious decrease in the winter period, due to low temperatures and physical draught. The decrease in chlorophyll a and b, was already detected after one year of treatment with simultaneous changes in a/b ration. An increase of anthocyanins amount was detected as well.
Published in DiRROS: 19.01.2024; Views: 163; Downloads: 41
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4. Biokemijske analize (API ZYM testi) dominantnih parazitskih in saprofitskih gliv črnega bora (Pinus nigra Arn.)Maja Jurc, Nada Gogala, 1996, original scientific article Abstract: Prispevek obravnava uporabo nekaterih biokemijskih analiz (API ZYM testov) pri pojasnjevanju vloge petih dominantnih endofitnih gliv (Cyclaneusma niveum (Pers.:Fr.) DiCosmo, Perdo & Minter, Cenangium ferruginosum Fr., Phialophora hoffmannii (Beyma) Schol-Schwarz, Cyclaneusma minus (Butin) DiCosmo, Perdo & Minter ter Hormonema dematioides Lagerberg & Melin), izoliranih iz iglic črnega bora. Ugotovljena je podobnost intracelularne in ekstarcelularne encimske aktivnosti analiziranih gliv. Pri vseh glivah je ugotovljena lipolitska aktivnost. Biokemijske analize podgobja lahko le delno nakažejo, v katero prehranjevalno skupino uvrščamo glivo (parazit, šibek parazit, saprofit)
Keywords: endofitne glive, črni bor, Pinus nigra Arn., encimi, latentna okužba, patogenost
Published in DiRROS: 23.08.2023; Views: 348; Downloads: 97
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5. Fitotoksičnost svinca in ektomikoriza gospodarsko pomembnih drevesnih vrstDominik Vodnik, Nada Gogala, 1996, original scientific article Abstract: V prispevku je opisana problematika fitotoksičnosti svinca, ki je lahko v povezavi z zakisanjem tal eden od pomembnih stresnih dejavnikov tudi v gozdnem ekosistemu. Prikazano je pojavljanje svinca v tleh, učinki njegove toksičnosti na fizioligijo rastlin in gliv, ter mehanizmi tolerance. Nakazana je vloga mikorizne simbioze pri omejevanju privzema svinca v rastlino in v omejevanju toksičnega delovanja. Pri tem so pregledno zajeti različni laboratorijski in terenski poskusi predvsem na ekonomsko pomembnih drevesnih vrstah. Poleg vpliva na drevesne vrste in simbiozo je prikazan je prikazan tudi vpliv svinca na glive s poudarkom na mehanizmih privzema in imobilizacije ter na toleranci ektomikoriznih gliv. S stališča fitotoksičnosti svinca je obravnavan ekološki pomen mikorizne simbioze ter perspektive nadaljnih raziskav
Keywords: svinec, fitotoksičnost, mikoriza, glive
Published in DiRROS: 23.08.2023; Views: 372; Downloads: 94
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6. Ribiške zgodbe v šoli : priročnik za učitelje tretje triade osnovnih šolLucija Čok, Tina Čok, Urška Bratož, Irina Moira Cavaion, Anna Maria Grego, 2023, dictionary, encyclopaedia, lexicon, manual, atlas, map Abstract: Priročnik Ribiške zgodbe v šoli je namenjen predvsem osnovnošolskim učiteljicam in učiteljem tretje triade, ki bi želeli dopolniti, razširiti in poglobiti vsebine, predvidene v okviru nekaterih obveznih in izbirnih predmetov (etnologija – kulturna dediščina in načini življenja, zgodovina – odkrivajmo preteklost svojega kraja, geografija – raziskovanje domačega kraja (šolskega okoliša) in varstvo njegovega okolja, pa tudi slovenščina in italijanščina …). Ker je bilo ob omenjeni analizi obstoječih učnih načrtov mogoče opaziti izrazito pomanjkanje vsebin, povezanih z (morskim) ribištvom in življenjem ob morju, so v nadaljevanju navedeni nekateri predlogi za intenzivnejše vključevanje obmorskih vsebin v učni proces. Opisani so primeri tematsko prepletenih, toda ločenih učnih enot (o ribištvu, ribiški dediščini, zgodovini predelave rib v obmorskih mestih, terminologiji, povezani z ribištvom, kulinariki v povezavi s floro in favno Sredozemlja in podobne teme), v katerih so poleg okvirne vsebine določeni tudi operativni cilji, način dela, možnosti medpredmetnih povezav ter dodatna gradiva in delovni listi za uspešen izobraževalni proces, kar učiteljicam in učiteljem olajša pripravo učnih ur, načrtovanje projektnega dela in tudi dodatnih pedagoških dejavnosti. Seveda so ti predlogi navedeni samo kot smernice, ki jih učiteljice in učitelji lahko poljubno preoblikujejo.
Keywords: prehrambna kultura, prehrambna industrija, ribe, konzerviranje
Published in DiRROS: 18.07.2023; Views: 364; Downloads: 218
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10. Klinična prehrana onkološkega bolnika : ESPEN in ESMO smerniceKarla Berlec, Nada Rotovnik-Kozjek, 2022, published scientific conference contribution Abstract: Rakasta kaheksija je presnovna motnja, ki je povezana s slabšo kakovostjo življenja, slabšim odzivom na zdravljenje, številnejšimi zapleti med zdravljenjem in krajšim preživetjem. Rakasta bolezen je za človeško telo stres, ki mu sledi celoviti nevroendokrini in vnetni odziv. Spremeni se potreba po posameznih hranilih in uporaba hranil, presnovne spremembe so še dodatno poglobijo zaradi zdravljenja. Zato bolniki potrebujejo presnovnim potrebam prilagojeno prehrano. Ta se doseže z opredelitvijo njihovega prehranskega stanja. Prehransko stanje se lahko opredeli s prehranskim presejanjem ali natančnejšo oceno prehranskega stanja, katerega izvede ustrezno izobražen zdravnik, medicinska sestra ali klinični dietetik. S prehransko podporo onkoloških bolnikov preprečujemo podhranjenost bolnikov, katera močno pospeši kahektične procese, z njo poskušamo čim dlje ohranjati funkcionalno mišično maso ter s tem bolnikovo kondicijo in kvaliteto življenja. Prehranska podpora in terapije motenj prehranskega stanja predstavljajo del sodobne multidisciplinarne terapije onkoloških bolnikov, ki se izvaja po modelu vzporednih terapevtskih poti.
Keywords: onkološki bolniki, klinična prehrana, klinične smernice
Published in DiRROS: 16.01.2023; Views: 554; Downloads: 161
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