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Povzetek: Introduction. Despite the use of modern imaging techniques, the reliable preoperative assessment of Meckel's diverticulurn and related complications with this rare congenital anomaly of the gastrointestinal tract in adults is uncomrnon. Case presentation. This report presents the case of a 25 year old man who presented with a sudden onset of pain in the right lower abdomen and vomiting. On clinical examination the affected area was tender to palpation which revealed an elastic cylindrical formation situated deeply in the abdomen. Blumberg's sign was positive while the laboratory findings were stillwithin normal limits. An ultrasonography of the abdomen revealed an ileocaecal fluid collection containing thicker residue, which was suspicious for Meckel's diverticulum or a duplication cyst and ileus of the small bowel proximally from the formation described. Native radiogram of the abdomen in supine position has confirmed the presence of obstructive ileus at the level of the distal part of the small bowel. Surgery revealed an ileus and compression of the distal part of the small bowel due to the presence of an edematous Meckel's diverticulum. Conclusion. In view of the frequent use of ultrasonography in the evaluation of acute ahdomen, the diagnostic procedures could be rationalized and the time to surgery reduced if possible complicatioris due to Meckel's diverticulum would he considered in the differential diagnosis.
Objavljeno v DiRROS: 22.01.2024; Ogledov: 184; Prenosov: 42
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Povzetek: Background. The diagnostic method of choice for ileus was a plain abdominal film. However, in the recent years, x-ray has been increasingly replaced by ultrasonography which, in experienced hands, can reveal ileus at an earlier stage and also identify the cause and site of obstruction. Case report. We reported about a male patient who was admitted to the Department of Gastroenterologic Surgery with severe abdominal pain and vomiting. A plain abdominal film showed an obstructive ileus and pneumobilia. Ultrasound examination of the abdomen confirmed the presence of ileus of the small intestine and demonstrated a gallstone impacted in the distal ileum. It also disclosed a distorted gallbladder adhering to the duodenum. The patient was treated surgically and had an uneventful postoperative course. Conclusions. Ultrasonography, in addition to diagnosing the ileus caused by an ectopic gallstone, is also able to identify the aetiology and site of obstruction.
Objavljeno v DiRROS: 22.01.2024; Ogledov: 206; Prenosov: 41
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Povzetek: Urokinase plasminogen activator (uPA) and its inhibitors, PAI-1 and PAI-2, play an important role in iritercellular tissue degradation, thus promoting tumor cell invasion into the adjoining structures and metastasizing. Our studywas aimed to assess a possible prognostic value of uPA, PAI-1 and PAI-2 in a retrospective series of 87 patients with breast cancer stage I-III, whosecytosols were stored in the archives of the, Institute of Oncology in Ljubljana. The median follow-up was 35 months. The prognostic value of the established prognostic factors and uPA, PAI-1 and PAI-2 were evaluated by means of univariate statistical analysis and partial multivariate models. The obtained uPA values were very low and did not correlate with the disease free survival, whereas PAI-1 and PAI-2 significantly influenced the time to the first recurrence. Patients with PAI-1 values above 5 ng/mg proteins had statistically significantly worse disease free survival than the patients withlower PAI-1 values (58% vs. 85%). In the case of PAI-2, the situation wasjust the opposite: the patients with PAI-2 values exceeding 6.4 ng/mg proteins had statistically significantly better 3-year disease free survival than the patients with lower values (90% vs. 60%). Both, PAI-1 and PAl-2 retained their independent prognostic value, irrespective of the addition of the established prognostic factors to partial multivariate models, and only with locally advanced disease the prognostic value of PAI-1 was greater than that of PAI-2.
Objavljeno v DiRROS: 22.01.2024; Ogledov: 203; Prenosov: 49
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Povzetek: Predstavljeni so testi za napovedovanje izida zdravljenja tumorjev po kemo- inradioterapiji in poškodb normalnih tkiv po radioterapiji. Pregled je osredotočen na tiste teste, pri katerih je treba celice gojiti v pogojih in vitro. Poleg tega članek obravnava tudi korelacijo med napovednimi testi in izidom zdravljenja različnih vrst raka ter poškodbami normalnih tkiv.
Objavljeno v DiRROS: 22.01.2024; Ogledov: 186; Prenosov: 52
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Povzetek: On the basis of the hypothesis that the ultraviolet radiation is one of the main causes for damage at higher altitudes, we have monitored the effect of UVradiation on Norway spruce for two and a half years. The influence of UV-B radiation on Picea abies (L). Karst.seedlings cultured in pots in open greenhouses was examined by measuring photochemical efficiency of photosystem II, changes in chlorophyll a, b, and changes in anthocyanins. The seedlings were grown in a mixture of peat and vermiculite (4:1). We used Osram ultravitaluks bulbs as a source of UV-B radiation. In the experiment plants were treated with 21.24+-3.5 kJ/m2 and 31.9+-2.5 KJ/m2. The control plants were grown under ambient conditions in the greenhouse without artificial source of UV-B radiation. The mean yearly values were as high as 11.5+-5.2 kJ/m2. The photochemical efficiency of photosystem II (PS II) in experimental plants did not vary during the experiment. It showed obvious decrease in the winter period, due to low temperatures and physical draught. The decrease in chlorophyll a and b, was already detected after one year of treatment with simultaneous changes in a/b ration. An increase of anthocyanins amount was detected as well.
Objavljeno v DiRROS: 19.01.2024; Ogledov: 211; Prenosov: 49
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