1. Cytology of mediastinal tumorsMilivoj Mermolja, Izidor Kern, Marjeta Terčelj-Zorman, Marjan Jereb, 1997, izvirni znanstveni članek Povzetek: Our experience with cytological examinations of tumorous mediastinal lesions is evaluated. A group of 117 patients with mediastinal tumor have been included into the study. Among them carcinomas prevailed (60,7%), followed by lymphomas (18,8%), other tumors (15.4%) and thymic neoplasms (5.1%). Malignantor suspicious cells were found in 77.4% of patients with carcinoma. The cells indicating a possibility of non-Hodgkin's lymphoma were found in 9 out of 14 patients. In 5 out of 6 thymic neoplasms the cytological pattern wasconsistent with the diagnosis of thymic neoplasm. One case of thymoma was cytologically falsely diagnosed as malignant lymphoma. One case of neurofibroma was falsely diagnosed as adenocarcinoma. The sensitivity of cytological examinations was 67.5%. If 18 patients with diagnostically unsatisfactory material were excluded from the analysis, the sensitivity wouldincrease to 80.8%. Owing to the wide variety of primary and metastatic tumors that can occur in the mediastinum, apart from the routine cytological techniques, additional staining methods should be used. For final cytological diagnosis the integration of cytological findings with clinical and radiological data is often required. Owing to the characteristics of the obtained material and biological behaviour of some mediastinal tumors, some tumors cannot be definitively diagnosed by cytological examinations alone.
Objavljeno v DiRROS: 18.01.2024; Ogledov: 163; Prenosov: 45
 Celotno besedilo (1,10 MB) |
2. Natural IFN-[alpha] for non-small-cell lung cancer with pleural carcinosisBerta Jereb, Gabrijela Petrič-Grabnar, Marjeta Terčelj-Zorman, Marija Us-Krašovec, Renata Mažuran, Evgen Šooš, Janez Stare, 1993, izvirni znanstveni članek Ključne besede: rak (medicina), karcinom, pljuča, zdravljenje, interferoni
Objavljeno v DiRROS: 10.01.2024; Ogledov: 153; Prenosov: 44
Celotno besedilo (406,80 KB) |
3. |
4. |
5. |
6. Detection of early lung cancer lesions in surgical resections and in bronchial and transbronchial biopsiesTomaž Rott, Maja Jerše, Marjeta Terčelj-Zorman, Janez Eržen, 2006, objavljeni znanstveni prispevek na konferenci (vabljeno predavanje) Povzetek: Background. Overall bad progmpsis of lung is mostly due to too late detection of early lung cancer, which may be teated with good success. Therefore different diagnostic methods are developing for more efficient detection of early lung cancer: besides modern radiological, bronchoscopic methods with additional fluorescence techniques, quantitative cytological investigations, also histological and molecular investigations are included. History may reveal early preinvasive lung xcancer lesions, associated early during multistep lung carcinogemesis with molecular genetic changes. Patients and methods. Preinvasive epithelial lung cancer lesions we searched in two groups of patients. In the first group of 316 patients from the period March 2003 - August 2006, 498 bronchial and transbronchial biopsies were examined for squamous metaplasia and dysplasia, carcinoma in situ, and invasive tumours. Inthe second group of 238 patients from the period January 2004 - August 2006,resected primary lung tumours were analysed for preinvasive neuroendocrine tumours and atypical adenomatous hyperplasia. Resuots. The mostfrequent changes in bronchial and transbronchial biopsies were squamous metaplasia (46.5%), simple or goblet cell hyperplasia of the bronchial epithelium (44.3%), malignant tumours (20.66%) and squamous dysplasia (16.1%),but rare carcinoma in situ (0.63%). Diffuse idiopoathic pulmonary neuroendocrine cell hyperplasia was found in 15 (6.3%) cases in the vicinity of 238 resected lung cancer specimens, carcinoid in12 patients (5%), and mostly combined large neuroendocrine cancer in 21 patients (8.8%). Atypical denomatous hyperplasia was found in 2 patients. Conculsions. Classical histological analysis should be focused on detection of early preinvasive epithelial lung cancer lesions. (Abstract truncated at 2000 characters).
Objavljeno v DiRROS: 05.12.2023; Ogledov: 172; Prenosov: 49
Celotno besedilo (1,11 MB) |
7. Smernice za diagnostiko in zdravljenje bolnikov z rakom pljučJože Antonič, Tanja Bavčar-Vodovnik, Olga Cerar, Rok Cesar, Anton Crnjac, Andrej Debeljak, Majda Drnovšek, Janez Eržen, Matjaž Fležar, Jože Jerman, Maja Jerše, Peter Kecelj, Izidor Kern, Igor Kocijančič, Viljem Kovač, Nada Rotovnik-Kozjek, Karmen Kramer Vrščaj, Slavica Lahajnar, Ilonka Osrajnik, Tomaž Rott, Andreja A. Schwarzbartl-Pevec, Anja Simonič, Uroš Smrdel, Mihael Sok, Andreja Cirila Škufca Smrdel, Saša Štern, Marjeta Terčelj-Zorman, Nadja Triller, Matjaž Turel, Tomaž Varga, Bojan Veingerl, Barbara Vidergar-Kralj, Stanko Vidmar, Martina Vrankar, Vesna Zadnik, Branko Zakotnik, Jurij Zalar, Anton Zorko, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Objavljeno v DiRROS: 27.05.2020; Ogledov: 2070; Prenosov: 574
Celotno besedilo (647,73 KB) |
8. |
9. |
