61. Inter-person differences in isometric coactivations of triceps surae and tibialis anterior decrease in young, but not in older adults after 14 days of bed restMatjaž Divjak, Gašper Sedej, Nina Murks, Mitja Gerževič, Uroš Marušič, Rado Pišot, Boštjan Šimunič, Aleš Holobar, 2022, original scientific article Abstract: We examined activation patterns of the gastrocnemius medialis (GM), gastrocnemius lateralis (GL), soleus (SO), and tibialis anterior (TA) muscles in eight older (58.4 ± 3.3 years) and seven young (23.1 ± 2.9 years) participants, before and after 14 days of horizontal bed rest. Visual feedback on the exerted muscle torque was provided to the participants. The discharge patterns of individual motor units (MUs) were studied in three repetitions of isometric plantar flexion at 30 and 60% of Maximum Voluntary Contraction (MVC), before, and 1 day after the 14-day bed rest, respectively. In the GL and GM muscles, the older participants demonstrated higher MU discharge rates than the young, regardless of the contraction level, both before and after the bed rest. In the TA and SO muscles, the differences between the older and young participants were less consistent. Detailed analysis revealed person-specific changes in the MU discharge rates after the bed rest. To quantify the coactivation patterns we calculated the correlation coefficients between the cumulative spike trains of identified MUs from each muscle, and measured the root mean square difference of the correlation coefficients between the trials of the same session (intra-session variability) and between different sessions (inter-session variability) in each participant (intra-person comparison) and across participants (inter-person comparison). In the intra-person comparison, the inter-session variability was higher than the intra-session variability, either before or after the bed rest. At 60% MVC torque, the young demonstrated higher inter-person variability of coactivation than the older participants, but this variability decreased significantly after the bed rest. In older participants, inter-person variability was consistently lower at 60% than at 30% MVC torque. In young participants, inter-person variability became lower at 60% than at 30% MVC torque only after the bed rest. Precaution is required when analyzing the MU discharge and coactivation patterns, as individual persons demonstrate individual adaptations to aging or bed rest.
Keywords: high density electromyography, muscle disuse, motor units, discharge rate, aging
Published in DiRROS: 05.09.2022; Views: 647; Downloads: 362
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62. Risk factors for systemic reactions in typical cold urticaria : results from the COLD-CE studyMojca Bizjak, Mitja Košnik, Dejan Dinevski, Simon Francis Thomsen, Daria Fomina, Elena Borzova, Kanokvalai Kulthanan, Raisa Meshkova, Dalia Melina Ahsan, Mona Al-Ahmad, Jovan Miljković, Dorothea Terhorst, Marcus Maurer, 2022, original scientific article Abstract: Background. Cold urticaria (ColdU), i.e. the occurrence of wheals or angioedema in response to cold exposure, is classified into typical and atypical forms. The diagnosis of typical ColdU relies on whealing in response to local cold stimulation testing (CST). It can also manifest with cold-induced anaphylaxis (ColdA). We aimed to determine risk factors for ColdA in typical ColdU. Methods. An international, cross-sectional study COLD-CE was carried out at 32 urticaria centers of reference and excellence (UCAREs). Detailed history was taken and CST with an ice cube and/or TempTest® performed. ColdA was defined as an acute cold-induced involvement of the skin and/or visible mucosal tissue and at least one of: cardiovascular manifestations, difficulty breathing, or gastrointestinal symptoms. Results. Of 551 ColdU patients, 75% (n=412) had a positive CST and ColdA occurred in 37% (n=151) of the latter. Cold-induced generalized wheals, angioedema, acral swelling, oropharyngeal/laryngeal symptoms, and itch of earlobes were identified as signs/symptoms of severe disease. ColdA was most commonly provoked by complete cold water immersion and ColdA caused by cold air was more common in countries with a warmer climate. Ten percent (n=40) of typical ColdU patients had a concomitant chronic spontaneous urticaria (CSU). They had a lower frequency of ColdA than those without CSU (4% vs 39%, p=0.003). We identified the following risk factors for cardiovascular manifestations: previous systemic reaction to a Hymenoptera sting, angioedema, oropharyngeal/laryngeal symptoms, and itchy earlobes. Conclusion. ColdA is common in typical ColdU. High-risk patients require education about their condition and how to use an adrenaline autoinjector.
Keywords: urticaria, risk factors, epinephrine - therapeutic use, self administration, intramuscular injections - methods, cold urticaria, systemic reactions, adrenaline autoinjector
Published in DiRROS: 31.08.2022; Views: 564; Downloads: 231
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63. Epidemiology and risk factors of self-reported systemic allergic reactions to a Hymenoptera venom in beekeepers worldwide : a protocol for a systematic review of observational studiesTanja Carli, Igor Locatelli, Mitja Košnik, Andreja Kukec, 2022, review article Abstract: Introduction Systemic allergic reaction (SAR) to a Hymenoptera venom is a potentially life-threatening disorder. The rate of SAR between beekeepers in comparison with a healthy individual is different. The risk for an SAR is particularly high in beekeepers due to their persistent or seasonal exposure to the stinging Hymenoptera. We aim to provide a critical appraisal and a synthesis of evidence-based data from epidemiological observational studies, focusing on SARs to a Hymenoptera venom and the associated risk factors for SARs in beekeepers worldwide. Methods and analysis Searching will include seven electronic databases for published studies without language restrictions, from inception up to 3 August 2021, and it will be rerun for all electronic databases prior publication. Only epidemiological observational studies in beekeepers will be included. The risk of bias in the included studies will be appraised by using the Joanna Briggs Institute Critical Appraisal Checklist for Analytical Cross-Sectional Studies and the Newcastle-Ottawa Scale, adapted for cross-sectional studies. For the certainty of evidence, the Grading of Recommendations Assessment, Development and Evaluation approach will be used. Qualitative synthesis will be presented in a tabulated format with the selected characteristics across primary studies and the main outcome of interest. A meta-analysis is planned to be performed if there will be a sufficient number of homogeneous studies with complete data. The Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols 2015 statement will guide the reporting of this systematic literature review. Ethics and dissemination No ethics approval is needed to conduct the systematic literature review since it will be solely based on the published literature. Findings will be disseminated through the relevant conferences, peer-review and open-access journals.
Keywords: systemic allergic reaction (SAR), Hymenoptera venom, systematic literature review
Published in DiRROS: 31.08.2022; Views: 671; Downloads: 307
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64. Evaluation of thermal conductivity estimation models with laboratory-measured thermal conductivities of sedimentsSimona Adrinek, Rao Martand Singh, Mitja Janža, Mateusz Żeruń, Grzegorz Ryżyński, 2022, original scientific article Abstract: Thermal conductivity is one of the key parameters for estimating low-temperature geothermal potential. In addition to field techniques, it can be determined based on physical parameters of the sediment measured in the laboratory. Following the methodology for cohesive and non-cohesive sample preparation, laboratory measurements were carried out on 30 samples of sediments. Density, porosity and water content of samples were measured and used in thermal conductivity estimation models (TCEM). The bulk thermal conductivity (λb) calculated with six TCEMs was compared with the measured λb to evaluate the predictive capacity of the analytical methods used. The results show that the empirical TCEMs are suitable to predict the λb of the analysed sediment types, with the standard deviation of the residuals (RMSE) ranging from 0.11 to 0.35 Wm−1 K−1. To improve the fit, this study provides a new modified parameterisation of two empirical TCEMs (Kersten and Côté&Konrad model) and, therefore, suggests the most suitable TCEMs for specific sample conditions. The RMSE ranges from 0.11 to 0.29 Wm−1 K−1. Mixing TCEM showed an RMSE of up to 2.00 Wm−1 K−1, meaning they are not suitable for predicting sediment λb. The study provides an insight into the analytical determination of thermal conductivity based on the physical properties of sediments. The results can help to estimate the low-temperature geothermal potential more quickly and easily and promote the sustainable use of this renewable energy source, which has applications in environmental and engineering science.
Keywords: thermal conductivity, non-cohesive sediment, cohesive sediment, estimation model
Published in DiRROS: 25.08.2022; Views: 595; Downloads: 261
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65. Poročilo o spremljanju stanja gozdov za leto 2021 : vsebinsko poročilo o spremljanju stanja gozdov v skladu s Pravilnikom o varstvu gozdov (2009)Mitja Ferlan, Andrej Grah, Janez Kermavnar, Lado Kutnar, Nikica Ogris, Anže Martin Pintar, Matej Rupel, Primož Simončič, Mitja Skudnik, Urša Vilhar, Daniel Žlindra, 2022, final research report Keywords: varstvo gozdov, monitoring, stanje gozdov, zdravstveno stanje krošenj, popis povzročiteljev poškodb, meteorološke meritve, osutost dreves, poročila, Slovenija
Published in DiRROS: 01.07.2022; Views: 723; Downloads: 249
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66. What could be 3DForEcoTech COST Action contribution to National Forest Inventories : presented at the 3DForEcoTech workshop, 15.06.2022, PragueGal Kušar, Mitja Skudnik, Luka Krajnc, Anže Martin Pintar, 2022, unpublished conference contribution Keywords: National Forest Inventory, dendrometry, improvement, field mensuration, Slovenia
Published in DiRROS: 28.06.2022; Views: 778; Downloads: 0 |
67. Patch testing with the European baseline series and 10 added allergens : single centre study of 748 patientsMojca Bizjak, Katja Adamič, Nisera Bajrović, Renato Eržen, Maja Jošt, Peter Kopač, Mitja Košnik, Nika Lalek, Mihaela Zidarn, Dejan Dinevski, 2022, original scientific article Abstract: Background. The European baseline series (EBS) of contact allergens is subject to change. An allergen is considered for inclusion when routine patch testing of patients with suspected contact dermatitis results in ≥ 0.5% prevalence rate. Objectives. We aimed to determine the frequency of sensitizations to 30 EBS allergens and 10 locally added allergens. Additionally, we assessed the strength and evolution of reactions to all tested allergens and co-reactivity of additional allergens. Methods. Patch testing with our baseline series of 40 allergens was done in 748 consecutive adults. Tests were applied to the upper back and removed by patients after 48 hours. Readings were done on day 3 (D3) and D6 or D7 (D6/7). Positive reactions fulfilled the criteria of at least one plus (+) reaction. Retrospective analysis was done. Results. Eight allergens not listed in the EBS had ≥ 0.5% prevalence rate (i.e., cocamidopropyl betaine, thiomersal, disperse blue mix 106/124, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, propylene glycol, Compositae mix II, and dexamethasone-21-phosphate), and 16.6% of positive reactions would have been missed without D6/7 readings. Conclusion. We propose further studies to evaluate whether cocamidopropyl betaine, disperse blue mix 106/124, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, and Compositae mix II need to be added to the EBS.
Keywords: allergy and immunology -- diagnosis, hypersensitivity -- diagnosis, skin tests, clinical epidemiology, baseline series, contact sensitization, patch tests, simultaneous reactivity
Published in DiRROS: 24.06.2022; Views: 601; Downloads: 217
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68. Gozdnovegetacijska karta SlovenijeŽivko Košir, Marja Zorn-Pogorelc, Janko Kalan, Lojze Marinček, Ivan Smole, Lojze Čampa, Marjan Šolar, Boštjan Anko, Marko Accetto, Dušan Robič, Valentin Toman, Lojze Žgajnar, Niko Torelli, Irena Tavčar, Lado Kutnar, Anton Kralj, 2007, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: gozdnovegetacijska karta, digitalni zapis, elektronski medij, CD-Rom, fitocenološka karta, fitocenologija, zgodovina
Published in DiRROS: 22.06.2022; Views: 828; Downloads: 1191
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70. Oljka, sušne razmere, tla in deficitno namakanjeMaja Podgornik, Jakob Fantinič, Milena Bučar-Miklavčič, Vasilij Valenčič, Bojan Butinar, Dominik Vodnik, Helena Gramc, Damijana Kastelec, Mitja Ferlan, Marina Pintar, 2022, scientific monograph Abstract: Monografija obsega pregled znanja na področju prilagoditve oljk na sušne razmere ter pregled tehnologij namakanja oljk. Res je, da je oljka manj zahtevna vrsta, saj lahko uspeva v izjemno skeletnih tleh in je zelo dobro prilagojena na pomanjkanje vode v njih, a kljub fiziološkim prilagoditvam, lahko sušne razmere negativno vplivajo na rast, razvoj in pridelek oljk. Sušni stres lahko pri oljkah blažimo z deficitnim namakanjem. Deficitni način namakanja je oblika nadgradnje namakanja, saj z nadzorovanim primanjkljajem vode zagotovimo kakovost pridelka, obstoj rastline ter hkrati zmanjšamo porabo vode in energije. Deficitni način namakanja, temelji na načelu, da obrok vode dodamo takrat, ko ga rastlina najbolj gospodarno uporabi. Pri tem je ključnega pomena poznavanje rastlinske vrste, njenih anatomskih in morfoloških značilnosti, fizioloških prilagoditev na sušo, biokemijski odziv na stresne dejavnike in s tem vpliv na kakovost plodov in olja. Poleg tega je potrebno tudi poznavanje dejavnikov, ki vplivajo na pridelovalne sposobnosti oljk, kot so lastnosti tal s svojimi vodno zadrževalnimi sposobnostmi ter dostopna voda v tleh. Ob skrbnem upoštevanju potreb rastline in okoljskih razmer z ustreznim delovanjem namakalnega sistema lahko dosežemo usklajeno razmerje med kakovostjo in količino pridelka o hkratnem varovanju potencialov naravnih virov.
Published in DiRROS: 14.06.2022; Views: 739; Downloads: 481
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