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Abstract: Animal models of colorectal carcinogenesis represent invaluable research tool for investigating colorectal cancer (CRC). Experimentally induced tumours in laboratory animals provide opportunity for studying certain aspects of tumoursthat cannot be effectively studied in humans. Significant information on human CRC aetiology or factors influencing it has derived from studies using dimethylhydrazine (DMH) model that is one of the experimental models appreciated for its morphological similarity to human CRC. Today, DMH model represents useful research tool for the studies of colon carcinogens and chemopreventive agents. The review offers insight into morphogenesis and genetic alterations of DMH induced colorectal epithelial tumours in rats.
Published in DiRROS: 14.02.2024; Views: 138; Downloads: 33
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Abstract: Belite-sulfoaluminate (BCSA) cements are low-carbon mineral binders, which require low energy consumption and allow the incorporation of various secondary raw materials in the clinker raw meal. In this study two types of unprocessed steel slags, coming from stainless steel production, were incorporated in the BCSA clinkers. The clinker phase composition, clinker reactivity, and the compressive strength of the cement were studied to evaluate the possible use of the slag in BCSA clinkers. The cement clinkers were synthesized by using natural raw materials, white titanogypsum, mill scale, as well as two different steel slags: (i) EAF S slag, which is a by-product of melting the recycled steel scrap in an electric arc furnace, and (ii) la dle slag as a by-product of the processes of secondary metallurgy, in various quantities. Raw mixtures with two different targeted phase compositions varying in belite, calcium sulfoaluminate and ferrite phases were sintered at 1250 °C. Clinker phases were determined by Rietveld quantitative phase analysis, while their distribution, morphology and incorporation of foreign ions in the phases were studied by SEM/EDS analysis. The clinker reactivity was determined by isothermal calorimetry. BCSA cements were prepared by adding titanogypsum. The compressive strength of the cement pastes was determined after 7 days of hydration. The presence of a predicted major clinker phases was confirmed by Rietveld analysis, however periclase was also detected. Microscopy revealed subhedral grains of belite and euhedral grains of calcium sulfoaluminate phases, while ferrite occurred as an interstitial phase. The results showed differences in the microstructure and reactivity of the clinker and cement, which can be attributed to varying amounts of ettringite due to different slag types
Keywords: belite-sulfoaluminate cement, cement clinker, steel slags, clinker microstructure, cement reactivity
Published in DiRROS: 19.01.2024; Views: 208; Downloads: 84
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Keywords: podnebne spremembe, naravne ujme, gozdovi, kombinirana obnova gozdov, sadnja, inovativen pristop, Kočevska, Life IP CARE4CLIMATE
Published in DiRROS: 05.01.2024; Views: 265; Downloads: 79
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Abstract: Background. Gray-scale ultrasound (US) patterns are still the best indicators of the risk of malignancy and correlation with mammography and guidance to bioptical procedures are still the gold standard in breast diagnosis. But recent technological advancements in ultrasound offer new diagnostic capabilities that integrate conventional US imaging: 3D, CAD, perfusion imaging and elastography. Conclusions. The US technologies allow to differentiate and grade the vascularity of breast lesions (both with conventional technologies and with contrast enhancers) and to evaluate the elastic properties of the normal and pathologic tissues (elastography). Both these technologies are on the way of becoming commer cially available on medium and high-end US instruments. But they must still be considered as research tools because their diagnostic efficacy requires more widely clinicaltesting.
Published in DiRROS: 01.12.2023; Views: 159; Downloads: 52
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Abstract: The analysis of the current state of fire statistics and data collection in Europe and other countries is needed to increase awareness of how fire incidents affect buildings and to support pan-European fire prevention and fire mitigation mea- sures. The terminology and data collected regarding fire incidents in buildings in the EU Member States were mapped to obtain meaningful datasets to determine common terminology, collection methodology, and data interpretation system. An extensive literature review showed that fire data collection systems have been instrumental in informing firefighting strategies, evidence-based planning, prevention, and educational programmes. Differences and similarities between fire data collection systems were also investigated. The amount and quality of the information in fire statistical recording systems appear to be influenced by the complexity and structure with which the data are collected. The analysis also examined the existing fire statistics in the EU Member States and a few other countries. Finally, a detailed investigation of the number of fires, fire deaths, and injuries from 2009 to 2018 in several countries was examined based on data from a report by CTIF. The trends showed differences attributable to the existing fire statistical practices in terms of terminology and data collection, and interpretation. Part II proposes a common terminology for selected fire statistical variables. The results provide relevant information regarding fire safety at the European level and should be used to guide the development of more uniform fire statistics across Europe.
Keywords: fire statistics, fire incidents, fire statistical variable, terminology, data collection, data interpretation
Published in DiRROS: 13.11.2023; Views: 411; Downloads: 114
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