91. Posodobljena priporočila diagnostike in zdravljenja diferenciranega raka ščitniceNikola Bešić, Alenka Grošel, Andraž Perhavec, Andrej Doma, Andreja A. Schwarzbartl-Pevec, Andreja Klevišar Ivančič, Andrej Vogrin, Barbara Vidergar-Kralj, Barbara Gazić, Barbara Perić, Blaž Krhin, Cvetka Grašič-Kuhar, Edvard Pirnat, Ivana Žagar, Jerca Blazina, Katarina Zevnik, Katica Bajuk-Studen, Katja Zaletel, Margareta Strojan Fležar, Marko Hočevar, Marko Kokalj, Marta Dremelj, Nebojša Glumac, Olga Blatnik, Simona Gaberšček, Snežana Pavlović Djokić, Ulrika Klopčič, Veronika Kloboves-Prevodnik, Zorica Čekić, 2022, professional article Keywords: rak ščitnice, diferencirani rak, zdravljenje, smernice
Published in DiRROS: 01.07.2022; Views: 841; Downloads: 245
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92. Building of the Al-Containing secondary raw materials registry for the production of low CO2 mineral binders in South-Eastern European regionGorazd Žibret, Klemen Teran, Lea Žibret, Katarina Šter, Sabina Dolenec, 2021, original scientific article Abstract: The bottleneck in the process for increasing production of low CO2 mineral binders, based on BCSA (belite sulfoaluminate) clinkers, is the availability of Al-rich raw materials. For that purpose, a new registry of Al-containing secondary mineral residues (industrial and mine waste) has been developed and is presented in this paper. The methodology of creating the registry consists of three main steps: Gathering ideas, consolidation of ideas, and implementation. In order to achieve this, the following methodology was adopted: Analysis of similar registries by potential end-users and seeking potential solutions and tools to be used, and conducting 3 rounds of stakeholder consultations via workshops in order to determine crucial parameters and features the registry needs to contain. The key discussion points were about which data the registry needs to contain, who shall be the potential users, and what are the stakeholderʼs expectations from the registryʼs portal. Potential individual registry variables were identified as being relevant/irrelevant or available/unavailable, and potential solutions for the registrys sustainability were explored. Each Al-rich waste/residue data entry is divided into 10 slots, describing legal status, location, quantities, chemical (REE included), mineralogical, physical and radiological properties, life-cycle assessment, additional data, and data relevancy. The registry will act as a matchmaking tool between producers/holders of Al-rich secondary raw materials and potential producers of cement clinkers.
Keywords: cement, belite sulfoaluminate clinker, waste, by--product, deležniki
Published in DiRROS: 10.06.2022; Views: 555; Downloads: 328
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93. The valorisation of selected quarry and mine waste for sustainable cement production within the concept of circular economyEmilija Fidanchevski, Katarina Šter, Maruša Mrak, Ljiljana Kljajević, Gorazd Žibret, Klemen Teran, Bojan Poletanovic, Monika Fidanchevska, Sabina Dolenec, Ildikó Merta, 2022, original scientific article Abstract: The cement industry could potentially consume large amounts of solid industrial waste in order to improve its sustainability. The suitability of selected quarry and mine waste as secondary raw materials (SRM) was examined for the sustainable production of cement following the concept of a circular economy. The chemical, mineralogical, and radiological characterization of SRM was conducted in this study. Its potential use in low-carbon and low-energy belite-sulfoaluminate cement was investigated by incorporating the examined SRM into cement clinker. Various characterization methods were used to characterize the cement, including X-ray powder diffraction (XRD), thermal analysis (DTA/TG), and isothermal calorimetry. Depending on the chemical composition of the waste, lower or higher amounts were allowed to be incorporated into the raw clinker mixture for a targeted clinker phase composition. Among the samples, differences were observed in the phase composition of synthesized clinkers, which slightly influenced the reactivity of the cement but did not significantly change the compressive strength of the final product.
Keywords: mineralne surovine, rudarski odpadki, rudniki, kamnolomi, cement, klinker, krožno gospodarstvo, BCSA clinker, cement, circular economy, clinker, mine wastes, quarry waste
Published in DiRROS: 10.06.2022; Views: 623; Downloads: 325
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94. Pan-European phylogeography of the European roe deer (Capreolus capreolus)Kamila Plis, Magdalena Niedziałkowska, Tomasz Borowik, Johannes Lang, Mike Heddergott, Juha Tiainen, Aleksey Bunevich, Nikica Šprem, Ladislav Paule, Aleksey A. Danilkin, Marina Kholodova, Elena Zvychaynaya, Nadezhda Kashinina, Boštjan Pokorny, Katarina Flajšman, 2022, original scientific article Abstract: To provide the most comprehensive picture of species phylogeny and phylogeography of European roe deer (Capreolus capreolus), we analyzed mtDNA control region (610 bp) of 1469 samples of roe deer from Central and Eastern Europe and included into the analyses additional 1541 mtDNA sequences from GenBank from other regions of the continent. We detected two mtDNA lineages of the species: European and Siberian (an introgression of C. pygargus mtDNA into C. capreolus). The Siberian lineage was most frequent in the eastern part of the continent and declined toward Central Europe. The European lineage contained three clades (Central, Eastern, and Western) composed of several haplogroups, many of which were separated in space. The Western clade appeared to have a discontinuous range from Portugal to Russia. Most of the haplogroups in the Central and the Eastern clades were under expansion during the Weichselian glacial period before the Last Glacial Maximum (LGM), while the expansion time of the Western clade overlapped with the Eemian interglacial. The high genetic diversity of extant roe deer is the result of their survival during the LGM probably in a large, contiguous range spanning from the Iberian Peninsula to the Caucasus Mts and in two northern refugia.
Keywords: Capreolus capreolus, expansion, mitochondrial DNA, the Last Glacial Maximum refugia, the Quaternary history, Phylogenetics
Published in DiRROS: 26.05.2022; Views: 646; Downloads: 435
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97. Dynamic contrast-enhanced MRI in malignant pleural mesothelioma : prediction of outcome based on DCE-MRI measurements in patients undergoing cytotoxic chemotherapyMartina Vivoda Tomšič, Peter Korošec, Viljem Kovač, Sotirios Bisdas, Katarina Šurlan Popović, 2022, original scientific article Abstract: The malignant pleural mesothelioma (MPM) response rate to chemotherapy is low. The identification of imaging biomarkers that could help guide the most effective therapy approach for individual patients is highly desirable. Our aim was to investigate the dynamic contrast-enhanced (DCE) MR parameters as predictors for progression-free (PFS) and overall survival (OS) in patients with MPM treated with cisplatin-based chemotherapy. Methods: Thirty-two consecutive patients with MPM were enrolled in this prospective study. Pretreatment and intratreatment DCE-MRI were scheduled in each patient. The DCE parameters were analyzed using the extended Tofts (ET) and the adiabatic approximation tissue homogeneity (AATH) model. Comparison analysis, logistic regression and ROC analysis were used to identify the predictors for the patient's outcome. Results: Patients with higher pretreatment ET and AATH-calculated Ktrans and ve values had longer OS (P≤.006). Patients with a more prominent reduction in ET-calculated Ktrans and kep values during the early phase of chemotherapy had longer PFS (P =.008). No parameter was identified to predict PFS. Pre-treatment ET-calculated Ktrans was found to be an independent predictive marker for longer OS (P=.02) demonstrating the most favourable discrimination performance compared to other DCE parameters with an estimated sensitivity of 89% and specificity of 78% (AUC 0.9, 95% CI 0.74-0.98, cut off > 0.08 min-1). Conclusions: In the present study, higher pre-treatment ET-calculated Ktrans values were associated with longer OS. The results suggest that DCE-MRI might provide additional information for identifying MPM patients that may respond to chemotherapy.
Keywords: cisplatin, magnetic resonance imaging, mesothelioma
Published in DiRROS: 06.04.2022; Views: 1193; Downloads: 509
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98. Aktivacija citosolnih senzorjev DNA po obsevanjuTanja Jesenko, Maša Omerzel, Boštjan Markelc, Gregor Serša, Katarina Žnidar, Loree C. Heller, Maja Čemažar, 2021, published scientific conference contribution Keywords: citosolni senzorji, eksperimentalna onkologija, obsevanje
Published in DiRROS: 01.04.2022; Views: 627; Downloads: 199
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100. Priporočila za obravnavo bolnikov z melanomomMarko Hočevar, Primož Strojan, Janja Ocvirk, Barbara Perić, Olga Blatnik, Boštjan Luzar, Jože Pižem, Marko Boc, Tanja Mesti, Marija Ignjatović, Nežka Hribernik, Katarina Barbara Karner, Tomi Bremec, Tanja Planinšek Ručigaj, 2020, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: onkologija, melanomi, maligni melanomi, UV žarki, sončenje, sončne opekline, zaščitne kreme
Published in DiRROS: 18.03.2022; Views: 723; Downloads: 242
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