281. Poročilo o preskusu št.: LVG 2022-172 : vzorec št. 2022/00611Barbara Piškur, Ana Brglez, Maša Zagorac, Špela Jagodic, Zina Devetak, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, bor, borov smolasti rak, Fusarium circinatum Published in DiRROS: 19.10.2022; Views: 381; Downloads: 0 |
282. Poročilo o preskusu št.: LVG 2022-171 : vzorec št. 2022/00619Barbara Piškur, Ana Brglez, Maša Zagorac, Špela Jagodic, Zina Devetak, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, bor, borov smolasti rak, Fusarium circinatum Published in DiRROS: 19.10.2022; Views: 392; Downloads: 0 |
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284. Poročilo o preskusu št.: LVG 2022-168 : vzorec št. 2022/00604Barbara Piškur, Maša Zagorac, Špela Jagodic, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, bolezen tisočerih rakov, Geosmithia morbida, oreh, Juglans Published in DiRROS: 17.10.2022; Views: 397; Downloads: 0 |
285. Poročilo o preskusu št.: LVG 2022-167 : vzorec št. 2022/00625Barbara Piškur, Maša Zagorac, Špela Jagodic, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, bolezen tisočerih rakov, Geosmithia morbida, oreh, Juglans Published in DiRROS: 17.10.2022; Views: 364; Downloads: 0 |
286. Poročilo o preskusu št.: LVG 2022-166 : vzorec št. 2022/00614Barbara Piškur, Maša Zagorac, Špela Jagodic, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, bolezen tisočerih rakov, Geosmithia morbida, oreh, Juglans Published in DiRROS: 17.10.2022; Views: 372; Downloads: 0 |
287. Combination of pembrolizumab with electrochemotherapy in cutaneous metastases from melanoma : a comparative retrospective study from the InspECT and Slovenian Cancer RegistryLuca Giovanni Campana, Barbara Perić, Matteo Mascherini, Romina Spina, Christian Kunte, Erika Kis, Petra Rozsa, Pietro Quaglino, Maja Čemažar, Maša Omerzel, Gregor Serša, 2021, original scientific article Abstract: Electrochemotherapy (ECT) is an effective locoregional therapy for cutaneous melanoma metastases and has been safely combined with immune checkpoint inhibitors in preliminary experiences. Since ECT is known to induce immunogenic cell death, its combination with immune checkpoint inhibitors might be beneficial. In this study, we aimed to investigate the effectiveness of ECT on cutaneous melanoma metastases in combination with pembrolizumab. We undertook a retrospective matched cohort analysis of stage IIIC%IV melanoma patients, included in the International Network for sharing practices of ECT (InspECT) and the Slovenian Cancer Registry. We compared the outcome of patients who received the following treatments: (a) pembrolizumab alone, (b) pembrolizumab plus ECT, and (c) ECT. The groups were matched for age, sex, performance status, and size of skin metastases. The local objective response rate (ORR) was higher in the pembrolizumab-ECT group than in the pembrolizumab group (78% and 39%, p < 0.001). The 1 year local progression-free survival (LPFS) rates were 86% and 51% (p < 0.001), and the 1 year systemic PFS rates were 64% and 39%, respectively (p = 0.034). The 1 year overall survival (OS) rates were 88% and 64%, respectively (p = 0.006). Our results suggest that skin-directed therapy with ECT improves superficial tumor control in melanoma patients treated with pembrolizumab. Interestingly, we observed longer PFS and OS in the pembrolizumab-ECT group than in the pembrolizumab group. These findings warrant prospective confirmation. Keywords: electrochemotherapy, metastatic melanoma, skin metastases Published in DiRROS: 10.10.2022; Views: 491; Downloads: 245 Full text (701,05 KB) This document has many files! More... |
288. Poročilo o preskusu št.: LVG 2022-162 : vzorec št. 2022/00571Nikica Ogris, Maša Zagorac, Zina Devetak, Barbara Piškur, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, Geosmithia morbida, bolezen tisočerih rakov, Pterocarya fraxinifolia, program preiskav, Fusarium Published in DiRROS: 04.10.2022; Views: 478; Downloads: 0 |
289. Poročilo o preskusu št.: LVG 2022-163 : vzorec št. 2022/00437Nikica Ogris, Andreja Kavčič, Zina Devetak, Maša Zagorac, Špela Jagodic, Barbara Piškur, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, Geosmithia morbida, bolezen tisočerih rakov, Pterocarya fraxinifolia, program preiskav, Fusarium Published in DiRROS: 04.10.2022; Views: 432; Downloads: 0 |
290. Poročilo o preskusu št.: LVG 2022-161 : vzorec št. 2022/00555Nikica Ogris, Maša Zagorac, Zina Devetak, Barbara Piškur, 2022, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, bor, borov smolasti rak, Fusarium circinatum, program preiskav Published in DiRROS: 04.10.2022; Views: 372; Downloads: 0 |