1061. Development of an advanced methodology for assessing the environmental impacts of refurbishmentsTajda Potrč Obrecht, Sabina Jordan, Andraž Legat, Marcella Ruschi Mendes Saade, Alexander Passer, 2022, objavljeni znanstveni prispevek na konferenci Povzetek: The refurbishment of the building stock is one of the key tasks for reducing the future environmental emissions in building sector. The assessment of the environmental impacts (EI) of refurbishments with LCA methodology remains a challenge. In the current practice, the refurbishment is threated as the beginning of the new lifecycle and all the impacts associated with the previous life cycle are generally neglected. The exclusion of materials and components used prior to the refurbishment produces a data gap at the end-of-life since information about materials that remained in the building after the refurbishment are missing. Furthermore, no information about what impacts have already been considered in the past bears the risk that some of the impacts are double-counted. In order to overcome these problems, an advanced methodology for the assessment of the embodied impacts in the case of refurbishment was developed that combines two sub-methodologies that can also be used separately. The first submethodology is used for remodelling the input data in order to make them time corresponding. The second sub-methodology is used for the assessment of the EI in the residual value of building materials and components and is including the allocation of EI between the life cycle before and after the refurbishment. The combination of the two sub-methodologies enables a more realistic and accurate assessment of the environmental impacts. The methodology is illustrated on the case on the case of a façade refurbishment. Five different allocation approaches are investigated and the residual value is calculated after a selected time period before and after the refurbishment. For all the inputs time-corresponding data is modelled and used. The study showed that for the life cycle before the refurbishment the EI and the residual value are generally higher if time-corresponding data is used since the EI of the electricity mix are higher. It turned out that the use of different allocation approaches is favouring either the use of recycled or reused materials or the recycling of the materials at the end. The PEF and the cut-off approach with module D are both enhancing the circular economy. It can be assumed that they are likely to prevail in the future.
Ključne besede: LCA, refurbishment, allocation, module D, dynamic LCA
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1062. Cysteine proteinase inhibitors stefin A and stefin B in operable carcinoma of the head and neck : Inhibitorji cisteinskih proteinaz stefin A in stefin B pri operabilnem karcinomu glave in vratuPrimož Strojan, Marjan Budihna, Alojz Šmid, Branka Svetic, Ivan Vrhovec, Janko Kos, Janez Škrk, 2002, izvirni znanstveni članek Povzetek: Purpose. To evaluate the significance of cysteine proteinase inhibitors stefins (Stefs) A and B for a treatment decision and prognosis in operable squamous cell carcinoma of the head and neck (SCCHN). Patients and methods. Stefs A and B concentrations were determined immunobiochemically using ELISAs in cytosols prepared from the tumor and adjacent normal mucosa from 91 patients with operable SCCHN. The median follow-up period of patients alive atthe close-out date was 5.8 years (range, 5-9.3 years). Results. Stef A concentrations were significantly higher in tumor compared to normal mucosa (FM.05). When a subgroup with clinically palpable nodes) at presentation was taken into consideration (n=57), a significant difference in Stef A (P=0.03) and Stef B (P=0.02) concentrations between those with negative and positive necks, as determined on histopathological examination, was observed. On the univariate survival analysis, higher Stefsć concentrations turned to be prognostically advantageous. Stef A proved its independent prognostic significance also on multivariate setting. Conclusions. With the capability todifferentiate between the pN0- and pN+-stages of the disease in the patientsoriginally presented as node-positive, Stefs A and B could be useful markers when deciding on the extent of neck surgery. In addition, both Stefs proved to be reliable prognosticators for survival in patients with operable SCCHN.
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1067. Cerebral hyperperfusion syndrome after carotid angioplastyZoran Miloševič, Bojana Žvan, Marjan Zaletel, Miloš Šurlan, 2002, objavljeni znanstveni prispevek na konferenci Povzetek: Background. Cerebral hyperperfusion syndrome after carotid endarterectomy is an uncommon but well-de- fined entity. There are only few reports of "hyperperfusion injury" following carotid angioplasty. Case report. We report an unstable arterial hypertension and high grade carotid stenosis in a 58-year-old, right-handed woman. After a stroke in the territory of middle cerebral artery carotid angioplasty was per- formed in the patient. Among riskfactors, the long lasting arterial hypertension was the most pronounced. Immediately after the procedure, the patient was stable without any additionalneurologic deficit. The sec- ond day, the patient had an epileptic seizure and CT revealed a small haemorrhage in the left frontal lobe. Conclusions. The combination of a high grade carotid stenosis and unstable arterial pressure is probably an important prognostic factor in the pathogenesis of hyperperfusion syndrome.
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1069. European project BRAPHYQSJanez Burger, 2002, strokovni članek Povzetek: Background. Quality assurance in radiotherapy and brachytherapy is extremely important because errors that may occur during treatment process can be fatal for the patient. European Society for Therapeutic Radiology and Oncology has therefore founded BRAPHYQS, a special group that is responsible for the revision of quality assurance procedures of treatment performed in brachytherapy centers and for outlining common standards of work in European countries. Conclusions. The project BRAPHYQS has the following aims: (1) to publish European recommendations for implementing QA/QC in European brachytherapy centers; (2) to set up a central dosimetry audit in European brachytherapy centers (this task will be delegated to ESTRO-EQUAL laboratory at the Institute Gustave Roussy in Paris); (3) to set up a central audit for the geometrical reconstruction of source positions with a special test phantomthat will be available to each brachytherapy center. Hence, a series of"Baltas phantoms" will be elaborated and distributed to the brachytherapy centers in Europe; (4) to prepare a draft of booklet of QA/QC recommendations for testing the brachytherapy equipment and therapy planning systems.
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1070. Effects of 5-Gy irradiation on fertility and mating behaviour of Nezara viridula (Heteroptera: Pentatomidae)Alenka Žunič Kosi, Andrej Čokl, Gregor Serša, 2002, izvirni znanstveni članek Povzetek: Background. The polyphagous and cosmopolitan species Nezara viridula is one ofthe most important insect pests. The sterile insect technique (SIT) is a pest control strategy that involves sterilising males by exposing them to ionising radiation. Sterile males, released into wild population, mate with females, but eggs are not fertilised and the population gradually declines. Exposing insects to radiation during their growth stage might require lower sterilising dose. The aim of our study was to test whether 5-Gy irradiation of5th instar nymphs significantly affects: (1) moulting and further development of the irradiated nymphs, (2) the male's and female's reproduetivesystem and (3) the mating competitiveness of treated males, with special focus on vibrational communication. Methods: The 5th instar nymphs were irradiated with 5 Gy using X ray generator and monitored daily. Results: The observed effects of irradiation were: prolonged moulting increased mortality during development and during the first day of adult life, decreasedmales to females ratio, decreased fecundity, egg production, proportion of fertile eggs and progeny survival. The reaction of a male to stimulation with the model female calling song was tested. The irradiated and non-irradiated males responded to stimulation with emission of the eourtship song (MCrS). Temporal parameters of MCrS emitted by non-irradiated males differed when compared with those of irradiated ones. Conclusions: The 5-Gy irradiation of 5th instar nymphs did not affect mating behaviour. However since the irradiation during growth stage decreased the fertility and fecundity of emerged adults, this technique, in combination with certain othersuppression teehniques, could be a successful control strategy for management of Nezara viridula. On the other hand observed effects on moulting and further development of the irradiated nymphs could decrease the efficiencyand application of this strategy.
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