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Na voljo sta dva načina iskanja: enostavno in napredno. Enostavno iskanje lahko zajema niz več besed iz naslova, povzetka, ključnih besed, celotnega besedila in avtorja, zaenkrat pa ne omogoča uporabe operatorjev iskanja. Napredno iskanje omogoča omejevanje števila rezultatov iskanja z vnosom iskalnih pojmov različnih kategorij v iskalna okna in uporabo logičnih operatorjev (IN, ALI ter IN NE). V rezultatih iskanja se izpišejo krajši zapisi podatkov o gradivu, ki vsebujejo različne povezave, ki omogočajo vpogled v podroben opis gradiva (povezava iz naslova) ali sprožijo novo iskanje (po avtorjih ali ključnih besedah).

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11 - 20 / 2000
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11.
Advancing oxygen evolution catalysis with dual-phase nickel sulfide nanostructures
Neelakandan Marath Santhosh, Suraj Gupta, Vasyl Shvalya, Martin Košiček, Janez Zavašnik, Uroš Cvelbar, 2024, izvirni znanstveni članek

Povzetek: The production, conversion and storage of energy based on electrocatalysis, mainly assisted by oxygen evolution reaction (OER), plays a crucial role in alkaline water electrolyzers (AWEs) and fuel cells. Nevertheless, the insufficient availability of highly efficient catalyst materials at a reasonable cost that overcome the sluggish electrochemical kinetics of the OER is one of the significant obstacles. Herein, we report a fast and facile synthesis of vapor phase deposition of dual-phase nickel sulfide (Ni-sulfide) using low-temperature annealing in the presence of H2S and demonstrated as an efficient catalyst for OER to address the issues with sluggish electrochemical kinetics. The dual-phase Ni-sulfide structures consist of densely packed 10–50 μm microcrystals with 40–50 individual dual-phase layers, such as NiS and Ni7S6. As an electrocatalyst, the dual-phase Ni-sulfide exhibits excellent OER activity by achieving a current density of 10 mA/cm2 at an overpotential (η10) of 0.29 V and excellent electrochemical stability over 50 h. Besides, the Ni-sulfide displays considerable electrochemical robustness in alkaline conditions and forms OER-active Ni-oxide/hydroxide species during the process. Using an energy-efficient synthesis method, the fabricated unique crystalline nanodesign of dual-phase Ni-sulfide could open new pathways for the controlled synthesis of a high-efficiency group of electrocatalysts for a long-time stable electrochemical catalytic activity.
Ključne besede: electrocatalysts
Objavljeno v DiRROS: 17.01.2025; Ogledov: 65; Prenosov: 20
.pdf Celotno besedilo (9,26 MB)
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12.
Smart bionanomaterials for treatment and diagnosis of inflammatory bowel disease
Spase Stojanov, Aleš Berlec, 2024, pregledni znanstveni članek

Povzetek: Inflammatory bowel disease (IBD) encompasses a group of chronic inflammatory disorders that affect the gastrointestinal tract, with Crohn’s disease and ulcerative colitis being the primary subtypes. Diagnosis and treatment of IBD are challenging due to their unknown etiology and complex pathology. Smart bionanomaterials, which are biocompatible nanometer-sized materials that respond to external stimuli, can be used in the treatment and diagnosis of diseases. In the context of IBD, these materials can deliver drugs, primarily aminosalicylates, and corticosteroids, as well as live probiotics to the inflamed parts of the intestine, with a specific focus on the colon. The controlled release of drugs can be triggered by the conditions present in the IBD-affected intestine, such as inflammation, anaerobic environment, neutral pH, and gut microbiota. This article provides an overview of the use of smart bionanomaterials, including hydrogels, nanoparticles, nanofibers, and hybrid systems. It discusses their manufacturing process and their ability to deliver active ingredients in response to various stimuli, such as pH, temperature, reactive oxygen species, magnetic field, and biomolecules, for the treatment of IBD. We also describe the use of smart probiotics, which have been genetically engineered to recognize specific stimuli and synthesize recombinant proteins for the treatment of IBD. The qualitative or quantitative response to inflammatory stimuli can be exploited in diagnostic applications, with some examples already developed. Smart bionanomaterials offer several advantages, such as encapsulation, targeted delivery, responsiveness to stimuli, and controlled release. These features make them a valuable adjunct tool in the diagnosis and treatment of IBD.
Ključne besede: bionanomaterials, responsive materials, gut microbiota
Objavljeno v DiRROS: 17.01.2025; Ogledov: 54; Prenosov: 23
.pdf Celotno besedilo (2,12 MB)
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13.
Predlog optimalnega števila in lokacij kontrolno-lovnih nastav za prezimele osebke osmerozobegasmrekovega lubadarja ( Ips typographus ) v Slovenijiza leto 2025
Nikica Ogris, Marija Kolšek, 2025, drugi znanstveni članki

Povzetek: Pripravili smo predlog optimalnega števila in lokacij kontrolno-lovnih nastav za prezimele osebke osmerozobega smrekovega lubadarja (Ips typographus ) (nastave I. serije) za leto 2025. Pri pripravi smo sledili predlogu postopka za določitev optimalnega števila in lokacij kontrolno-lovnih nastav za osmerozobega smrekovega lubadarja. Predlagamo, da se nastave I. serije v letu 2025 položi na88 lokacijah.
Ključne besede: gozdovi, varstvo gozdov, kontrolno-lovne nastave, postopek optimizacije, osmerozobi smrekov lubadar, Ips typographus, smreka, Picea abies, spremljanje, monitoring, zatiranje
Objavljeno v DiRROS: 17.01.2025; Ogledov: 53; Prenosov: 25
.pdf Celotno besedilo (565,37 KB)
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14.
New treatment approaches for Clostridioides difficile infections : alternatives to antibiotics and fecal microbiota transplantation
Tomaž Bratkovič, Abida Zahirović, Maruša Bizjak, Maja Rupnik, Borut Štrukelj, Aleš Berlec, 2024, pregledni znanstveni članek

Povzetek: Clostridioides difficile causes a range of debilitating intestinal symptoms that may be fatal. It is particularly problematic as a hospital-acquired infection, causing significant costs to the health care system. Antibiotics, such as vancomycin and fidaxomicin, are still the drugs of choice for C. difficile infections, but their effectiveness is limited, and microbial interventions are emerging as a new treatment option. This paper focuses on alternative treatment approaches, which are currently in various stages of development and can be divided into four therapeutic strategies. Direct killing of C. difficile (i) includes beside established antibiotics, less studied bacteriophages, and their derivatives, such as endolysins and tailocins. Restoration of microbiota composition and function (ii) is achieved with fecal microbiota transplantation, which has recently been approved, with standardized defined microbial mixtures, and with probiotics, which have been administered with moderate success. Prevention of deleterious effects of antibiotics on microbiota is achieved with agents for the neutralization of antibiotics that act in the gut and are nearing regulatory approval. Neutralization of C. difficile toxins (iii) which are crucial virulence factors is achieved with antibodies/antibody fragments or alternative binding proteins. Of these, the monoclonal antibody bezlotoxumab is already in clinical use. Immunomodulation (iv) can help eliminate or prevent C. difficile infection by interfering with cytokine signaling. Small-molecule agents without bacteriolytic activity are usually selected by drug repurposing and can act via a variety of mechanisms. The multiple treatment options described in this article provide optimism for the future treatment of C. difficile infection.
Ključne besede: microbiota, immunomodulators
Objavljeno v DiRROS: 17.01.2025; Ogledov: 53; Prenosov: 22
.pdf Celotno besedilo (4,12 MB)
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15.
Analiza ohranjenosti nosilnosti lesenih stropnikov v Zoisovem gradu, Stara Fužina 216, 4265 Bohinjsko jezero
Luka Krajnc, 2024, elaborat, predštudija, študija

Ključne besede: les, gostota, nosilnost
Objavljeno v DiRROS: 17.01.2025; Ogledov: 44; Prenosov: 1
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16.
Poročilo o preskusu št.: LVG 2025-014 : vzorec št. 2024/00782
Maarten De Groot, Eva Groznik, 2025, izvedensko mnenje, arbitražna odločba

Ključne besede: varstvo gozdov, morfološke analize
Objavljeno v DiRROS: 17.01.2025; Ogledov: 49; Prenosov: 0
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17.
Modified vaginal lactobacilli expressing fluorescent and luminescent proteins for more effective monitoring of their release from nanofibers, safety and cell adhesion
Spase Stojanov, Tina Vida Plavec, Špela Zupančič, Aleš Berlec, 2024, izvirni znanstveni članek

Povzetek: Electrospun nanofibers offer a highly promising platform for the delivery of vaginal lactobacilli, providing an innovative approach to preventing and treating vaginal infections. To advance the application of nanofibers for the delivery of lactobacilli, tools for studying their safety and efficacy in vitro need to be established. In this study, fluorescent (mCherry and GFP) and luminescent (NanoLuc luciferase) proteins were expressed in three vaginal lactobacilli (Lactobacillus crispatus, Lactobacillus gasseri and Lactobacillus jensenii) and a control Lactiplantibacillus plantarum with the aim to use this technology for close tracking of lactobacilli release from nanofibers and their adhesion on epithelial cells. The recombinant proteins influenced the growth of the bacteria, but not their ability to produce hydrogen peroxide. Survival of lactobacilli in nanofibers immediately after electrospinning varied among species. Bacteria retained fluorescence upon incorporation into PEO nanofibers, which was vital for evaluation of their rapid release. In addition, fluorescent labelling facilitated efficient tracking of bacterial adhesion to Caco-2 epithelial cells, while luminescence provided important quantitative insights into bacterial attachment, which varied from 0.5 to 50% depending on the species. The four lactobacilli in dispersion or in nanofibers were not detrimental for the viability of Caco-2 cells, and did not demonstrate hemolytic activity highlighting the safety profiles of both bacteria and PEO nanofibers. To summarize, this study contributes to the development of a promising delivery system, tailored for local administration of safe vaginal lactobacilli.
Objavljeno v DiRROS: 17.01.2025; Ogledov: 55; Prenosov: 16
.pdf Celotno besedilo (2,68 MB)

18.
Poročilo o preskusu št.: LVG 2025-013 : vzorec št. 2024/00677
Maarten De Groot, Eva Groznik, 2025, izvedensko mnenje, arbitražna odločba

Ključne besede: varstvo gozdov, morfološke analize
Objavljeno v DiRROS: 17.01.2025; Ogledov: 31; Prenosov: 0
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19.
Poročilo o preskusu št.: LVG 2025-012 : vzorec št. 2024/00548
Maarten De Groot, Eva Groznik, 2025, izvedensko mnenje, arbitražna odločba

Ključne besede: varstvo gozdov, morfološke analize
Objavljeno v DiRROS: 17.01.2025; Ogledov: 38; Prenosov: 0
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20.
Poročilo o preskusu št.: LVG 2025-011 : vzorec št. 2024/00452
Maarten De Groot, Eva Groznik, 2025, izvedensko mnenje, arbitražna odločba

Ključne besede: varstvo gozdov, morfološke analize
Objavljeno v DiRROS: 17.01.2025; Ogledov: 32; Prenosov: 0
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