71. Priporočila za obravnavo bolnikov s pljučnim rakomMartina Vrankar, Nina Boc, Izidor Kern, Aleš Rozman, Karmen Stanič, Tomaž Štupnik, Mojca Unk, Maja Ebert Moltara, Vesna Zadnik, Katja Adamič, Jernej Benedik, Marko Bitenc, Jasna But-Hadžić, Anton Crnjac, Eva Ćirić, Tanja Čufer, Goran Gačevski, Marta Globočnik Kukovica, Kristina Gornik-Kramberger, Maja Ivanetič Pantar, Staša Jelerčič, Veronika Kloboves-Prevodnik, Mile Kovačević, Luka Ležaič, Mateja Marc-Malovrh, Katja Mohorčič, Bogdan Vidmar, Dušanka Vidovič, Gregor Vlačić, Ana Lina Vodušek, Rok Zbačnik, Ivana Žagar, 2022, ni določena Ključne besede: elektronske knjige
Objavljeno v DiRROS: 24.11.2022; Ogledov: 792; Prenosov: 248
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72. Bleomycin concentration in patientsʹ plasma and tumors after electrochemotherapy : a study from InspECT GroupAleš Grošelj, Maša Omerzel, Mojca Kržan, Tina Kosjek, Krisztina Bottyán, Helena Plešnik, Črt Jamšek, Maja Čemažar, Erika Kis, Gregor Serša, 2021, izvirni znanstveni članek Ključne besede: electrochemotherapy, electroporation, bleomycin
Objavljeno v DiRROS: 10.10.2022; Ogledov: 553; Prenosov: 265
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73. Risk factors for systemic reactions in typical cold urticaria : results from the COLD-CE studyMojca Bizjak, Mitja Košnik, Dejan Dinevski, Simon Francis Thomsen, Daria Fomina, Elena Borzova, Kanokvalai Kulthanan, Raisa Meshkova, Dalia Melina Ahsan, Mona Al-Ahmad, Jovan Miljković, Dorothea Terhorst, Marcus Maurer, 2022, izvirni znanstveni članek Povzetek: Background. Cold urticaria (ColdU), i.e. the occurrence of wheals or angioedema in response to cold exposure, is classified into typical and atypical forms. The diagnosis of typical ColdU relies on whealing in response to local cold stimulation testing (CST). It can also manifest with cold-induced anaphylaxis (ColdA). We aimed to determine risk factors for ColdA in typical ColdU. Methods. An international, cross-sectional study COLD-CE was carried out at 32 urticaria centers of reference and excellence (UCAREs). Detailed history was taken and CST with an ice cube and/or TempTest® performed. ColdA was defined as an acute cold-induced involvement of the skin and/or visible mucosal tissue and at least one of: cardiovascular manifestations, difficulty breathing, or gastrointestinal symptoms. Results. Of 551 ColdU patients, 75% (n=412) had a positive CST and ColdA occurred in 37% (n=151) of the latter. Cold-induced generalized wheals, angioedema, acral swelling, oropharyngeal/laryngeal symptoms, and itch of earlobes were identified as signs/symptoms of severe disease. ColdA was most commonly provoked by complete cold water immersion and ColdA caused by cold air was more common in countries with a warmer climate. Ten percent (n=40) of typical ColdU patients had a concomitant chronic spontaneous urticaria (CSU). They had a lower frequency of ColdA than those without CSU (4% vs 39%, p=0.003). We identified the following risk factors for cardiovascular manifestations: previous systemic reaction to a Hymenoptera sting, angioedema, oropharyngeal/laryngeal symptoms, and itchy earlobes. Conclusion. ColdA is common in typical ColdU. High-risk patients require education about their condition and how to use an adrenaline autoinjector.
Ključne besede: urticaria, risk factors, epinephrine - therapeutic use, self administration, intramuscular injections - methods, cold urticaria, systemic reactions, adrenaline autoinjector
Objavljeno v DiRROS: 31.08.2022; Ogledov: 614; Prenosov: 242
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74. Proteolytically activated CRAC effectors through designed intramolecular inhibitionVid Jazbec, Roman Jerala, Mojca Benčina, 2022, izvirni znanstveni članek Ključne besede: STIM1, Orai, TEV protease, PPV protease, calcium signaling, coiled-coil peptides
Objavljeno v DiRROS: 20.07.2022; Ogledov: 733; Prenosov: 437
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76. Patch testing with the European baseline series and 10 added allergens : single centre study of 748 patientsMojca Bizjak, Katja Adamič, Nisera Bajrović, Renato Eržen, Maja Jošt, Peter Kopač, Mitja Košnik, Nika Lalek, Mihaela Zidarn, Dejan Dinevski, 2022, izvirni znanstveni članek Povzetek: Background. The European baseline series (EBS) of contact allergens is subject to change. An allergen is considered for inclusion when routine patch testing of patients with suspected contact dermatitis results in ≥ 0.5% prevalence rate. Objectives. We aimed to determine the frequency of sensitizations to 30 EBS allergens and 10 locally added allergens. Additionally, we assessed the strength and evolution of reactions to all tested allergens and co-reactivity of additional allergens. Methods. Patch testing with our baseline series of 40 allergens was done in 748 consecutive adults. Tests were applied to the upper back and removed by patients after 48 hours. Readings were done on day 3 (D3) and D6 or D7 (D6/7). Positive reactions fulfilled the criteria of at least one plus (+) reaction. Retrospective analysis was done. Results. Eight allergens not listed in the EBS had ≥ 0.5% prevalence rate (i.e., cocamidopropyl betaine, thiomersal, disperse blue mix 106/124, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, propylene glycol, Compositae mix II, and dexamethasone-21-phosphate), and 16.6% of positive reactions would have been missed without D6/7 readings. Conclusion. We propose further studies to evaluate whether cocamidopropyl betaine, disperse blue mix 106/124, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, and Compositae mix II need to be added to the EBS.
Ključne besede: allergy and immunology -- diagnosis, hypersensitivity -- diagnosis, skin tests, clinical epidemiology, baseline series, contact sensitization, patch tests, simultaneous reactivity
Objavljeno v DiRROS: 24.06.2022; Ogledov: 646; Prenosov: 237
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77. Razsvetlimo Slovenijo, razsvetlimo svet : foto poročilo ob prvi obletnici globalnega gibanja zaeliminacijo raka materničnega vratu, 17. 11. 2021Urška Ivanuš, Tine Jerman, Mojca Florjančič, Veronika Kloboves-Prevodnik, 2022, ni določena Ključne besede: program ZORA, globalna strategija, elektronske knjige
Objavljeno v DiRROS: 12.05.2022; Ogledov: 763; Prenosov: 341
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79. Staroselske kozmologije v okviru novih epistemoloških in političnih teženj globalnega JugaMarija Mojca Terčelj, 2021, izvirni znanstveni članek Povzetek: Bistvena razlika med staroselskimi verstvi in svetovnimi religijami je v pojmovanju odnosa »človek – narava«. Staroselska verstva dojemajo človeka kot enakovrednega akterja pri vzpostavljanju kozmične harmonije, torej ga postavljajo ob bok vsem drugim živim in neživim bitjem stvarstva, medtem ko ga svetovne religije umeščajo v središče sveta. Krščansko religiozno izročilo na eni strani ter kartezijanski ontološki dualizem in metodološki empirizem na drugi so močno vplivali na razvoj zahodnjaške znanstvene misli. Družbene in humanistične vede so v zadnjih desetletjih naredile velik korak – prispevale so k novim razlagam glo-balnih ekonomskih in socialnih zakonitosti ter hibridizacije etničnih identitet in začele tesneje sodelovati z empiričnimi znanostmi. Problem nastane, ko je zaradi lastne zazrtosti katera koli druga vrsta znanja diskvalificirana kot »neznanstvena«, »lokalna«, »romantična«, nepopolna. V začetku 21. stoletja je staroselska kozmologija vstopila v politični diskurz in ideologijo številnih socialnih gibanj globalnega Juga. Na podlagi primerjalne analize treh konkretnih staroselskih kozmoloških in religioznih modelov (odnos človek – narava) želi članek opozoriti na potrebo po pluralizmu miselnih konceptov in družbenih praks.
Ključne besede: človek - narava, staroselci, pačamamizem, ekologija, razvoj
Objavljeno v DiRROS: 22.03.2022; Ogledov: 682; Prenosov: 425
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80. Vodnik za zdravljenje z zdravilom lorlatinibMojca Unk, 2021, slovar, enciklopedija, leksikon, priročnik, atlas, zemljevid Ključne besede: nedrobnocelični rak pljuč, kemoterapija, lorlatinib, bolniki
Objavljeno v DiRROS: 17.03.2022; Ogledov: 715; Prenosov: 262
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