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Abstract: S citološkim pregledom brisa materničnega vratu (BMV, test PAP) uspešno odkrivamo predrakave spremembe na ploščatem epiteliju materničnega vratu, vendar je ocenjevanje BMV v veliki meri subjektivno in interpretacija ni vedno enostavna. Ker občutljivost testa ni 100 %, lahko ženske kljub rednim preventivnim BMV zbolijo za rakom materničnega vratu (RMV). Zato je kontrola kakovosti pregledovanja BMV in analiza postopkov glede na citološki izvid sestavni del vsakega presejalnega programa. Strokovni svet Onkološkega inštituta Ljubljana je v skladu s Pravilnikom za izvajanje preventivnega zdravstvenega varstba na primarni ravni imenoval strokovno komisijo in jo zadolžil, da ponovno pregleda in oceni brise materničnega vratu bolnic, ki so zbolele za RMV in ugotovi, ali so bili BMV pravilno ocenjeni. V pripsvku so predstavljeni rezultati revizije BMV in ugotovitve komisije.
Keywords: maternični vrat, test PAP, predrakave spremembe, novotvorbe, diagnostika, brisi, kontrola kakovosti
Published in DiRROS: 07.04.2020; Views: 1771; Downloads: 512
Full text (67,75 KB)

Abstract: The fungus Pseudodidymella fagi is spreading in Europe and causing leaf blotch of European beech, Fagus sylvatica. Between 2008 and 2017, outbreaks of P. fagi were observed on European beech in Switzerland, Germany (also on F. orientalis), Austria, and Slovakia. In Slovenia, leaf blotch symptoms were first observed on F. sylvatica in 2018. P. fagi was identified as the causal agent of the observed symptoms in Slovenia by morphological examinations together with sequencing of the internal transcribed spacer (ITS) region of the rDNA. This study links the fungus to the expansion of the known distribution of the disease to Slovenia, and based on in vitro pathogenicity trials, also to a new potential host, Quercus petraea. The pathogenicity tests confirmed F. sylvatica and F. orientalis as hosts for P. fagi, but not Castanea sativa, where pathogenicity to F. orientalis was proved for first time in vitro. Although Koch%s postulates could not be proven for C. sativa, it seems to be partially susceptible in vitro because some of the inoculation points developed lesions. Additionally, damage to Carpinus betulus related to P. fagi near heavily infected beech trees was observed in vivo but was not tested in laboratory trials. Based on the results and our observations in the field, it is likely that P. fagi has a wider host range than previously thought and that we might be witnessing host switching.
Keywords: Pycnopleiospora fagi, leaf blotch, pathogenicity test, inoculation test, Fagus orientalis, Fagus sylvatica, Quercus petraea, mycopappus-like propagule, Carpinus betulus, host switching
Published in DiRROS: 23.08.2019; Views: 2507; Downloads: 1569
Full text (4,90 MB)
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